63 items (Macaca fascicularis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SYNPO	Synaptopodin. (929 aa)
	MYLK	Myosin light chain kinase. (1914 aa)
	NEBL	Nebulette. (1014 aa)
	PALLD	Palladin, cytoskeletal associated protein. (1124 aa)
	PTK2	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
	ENSMFAP00000004462	Uncharacterized protein; Belongs to the tropomyosin family. (225 aa)
	TPM2	Tropomyosin 2; Belongs to the tropomyosin family. (322 aa)
	ACTA1	Actin alpha 1, skeletal muscle. (377 aa)
	LIMA1	LIM domain and actin binding 1. (761 aa)
	PDLIM3	PDZ and LIM domain 3. (364 aa)
	ENSMFAP00000006504	PDZ domain-containing protein. (285 aa)
	MYH7	Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
	FSCN1	Fascin. (493 aa)
	ENSMFAP00000009030	Uncharacterized protein; Belongs to the tropomyosin family. (241 aa)
	FHL3	Uncharacterized protein. (280 aa)
	MYH9	Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
	PDLIM4	PDZ and LIM domain 4. (329 aa)
	TPM4-2	Uncharacterized protein; Belongs to the tropomyosin family. (248 aa)
	ENSMFAP00000012855	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (309 aa)
	LDB3	LIM domain binding 3. (732 aa)
	ENSMFAP00000013730	EFhand_Ca_insen domain-containing protein. (97 aa)
	PDLIM1	PDZ and LIM domain 1. (330 aa)
	PDLIM5	PDZ and LIM domain 5. (625 aa)
	DAAM1	Dishevelled associated activator of morphogenesis 1. (1078 aa)
	TPM1	Uncharacterized protein; Belongs to the tropomyosin family. (326 aa)
	PXN	Paxillin. (1079 aa)
	SORBS1	Sorbin and SH3 domain containing 1. (1294 aa)
	AMOT	Angiomotin. (1099 aa)
	CYBA	Cytochrome b-245 alpha chain. (197 aa)
	CNN2	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (289 aa)
	SEPTIN9	Septin 9; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (586 aa)
	TRIP6	Thyroid hormone receptor interactor 6. (476 aa)
	BAG3	BCL2 associated athanogene 3. (575 aa)
	SEPTIN12	Septin 12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (358 aa)
	ZYX	Zyxin. (572 aa)
	LIMCH1	LIM and calponin homology domains 1. (1626 aa)
	FBLIM1	Filamin binding LIM protein 1. (375 aa)
	ABLIM3	Actin binding LIM protein family member 3. (690 aa)
	PGM5	Phosphoglucomutase 5; Belongs to the phosphohexose mutase family. (567 aa)
	MST1R	Macrophage stimulating 1 receptor. (1403 aa)
	MYH14	Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2036 aa)
	SHROOM4	Shroom family member 4. (1499 aa)
	TPM4	Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
	MYL12A	Myosin light chain 12A. (177 aa)
	ENSMFAP00000032124	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (290 aa)
	ACTN1	Alpha-actinin-1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (By similarity). (914 aa)
	PRICKLE4	Uncharacterized protein. (385 aa)
	FLNB	Filamin B. (2633 aa)
	TPM3	Uncharacterized protein; Belongs to the tropomyosin family. (285 aa)
	SYNPO2	Synaptopodin 2. (1261 aa)
	SIPA1L3	Signal induced proliferation associated 1 like 3. (1777 aa)
	PRKCZ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (583 aa)
	CORO1B	Coronin; Belongs to the WD repeat coronin family. (489 aa)
	C10orf113	Chromosome 10 open reading frame 113. (152 aa)
	FERMT2	Fermitin family member 2. (693 aa)
	ABLIM1	Actin binding LIM protein 1. (778 aa)
	ROR1	Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (923 aa)
	LPP	LIM domain containing preferred translocation partner in lipoma. (612 aa)
	ENSMFAP00000043282	Uncharacterized protein; Belongs to the tropomyosin family. (289 aa)
	MYH10	Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
	PDLIM7	PDZ and LIM domain 7. (441 aa)
	MYH6	Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
	ENSMFAP00000045970	Uncharacterized protein. (144 aa)

Your Current Organism:

Macaca fascicularis

NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABLIM1	ABLIM3	ENSMFAP00000040455	ENSMFAP00000026857	Actin binding LIM protein 1.	Actin binding LIM protein family member 3.	0.908
ABLIM3	ABLIM1	ENSMFAP00000026857	ENSMFAP00000040455	Actin binding LIM protein family member 3.	Actin binding LIM protein 1.	0.908
ACTA1	ACTN1	ENSMFAP00000005196	ENSMFAP00000034127	Actin alpha 1, skeletal muscle.	Alpha-actinin-1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (By similarity).	0.427
ACTA1	DAAM1	ENSMFAP00000005196	ENSMFAP00000015562	Actin alpha 1, skeletal muscle.	Dishevelled associated activator of morphogenesis 1.	0.440
ACTA1	ENSMFAP00000004462	ENSMFAP00000005196	ENSMFAP00000004462	Actin alpha 1, skeletal muscle.	Uncharacterized protein; Belongs to the tropomyosin family.	0.536
ACTA1	ENSMFAP00000009030	ENSMFAP00000005196	ENSMFAP00000009030	Actin alpha 1, skeletal muscle.	Uncharacterized protein; Belongs to the tropomyosin family.	0.536
ACTA1	ENSMFAP00000013730	ENSMFAP00000005196	ENSMFAP00000013730	Actin alpha 1, skeletal muscle.	EFhand_Ca_insen domain-containing protein.	0.427
ACTA1	ENSMFAP00000043282	ENSMFAP00000005196	ENSMFAP00000043282	Actin alpha 1, skeletal muscle.	Uncharacterized protein; Belongs to the tropomyosin family.	0.536
ACTA1	ENSMFAP00000045970	ENSMFAP00000005196	ENSMFAP00000045970	Actin alpha 1, skeletal muscle.	Uncharacterized protein.	0.465
ACTA1	MYH6	ENSMFAP00000005196	ENSMFAP00000045491	Actin alpha 1, skeletal muscle.	Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.727
ACTA1	MYH7	ENSMFAP00000005196	ENSMFAP00000007680	Actin alpha 1, skeletal muscle.	Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.605
ACTA1	MYH9	ENSMFAP00000005196	ENSMFAP00000009871	Actin alpha 1, skeletal muscle.	Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.419
ACTA1	MYL12A	ENSMFAP00000005196	ENSMFAP00000031951	Actin alpha 1, skeletal muscle.	Myosin light chain 12A.	0.465
ACTA1	PDLIM3	ENSMFAP00000005196	ENSMFAP00000006207	Actin alpha 1, skeletal muscle.	PDZ and LIM domain 3.	0.512
ACTA1	TPM1	ENSMFAP00000005196	ENSMFAP00000015571	Actin alpha 1, skeletal muscle.	Uncharacterized protein; Belongs to the tropomyosin family.	0.536
ACTA1	TPM2	ENSMFAP00000005196	ENSMFAP00000004804	Actin alpha 1, skeletal muscle.	Tropomyosin 2; Belongs to the tropomyosin family.	0.453
ACTA1	TPM3	ENSMFAP00000005196	ENSMFAP00000036541	Actin alpha 1, skeletal muscle.	Uncharacterized protein; Belongs to the tropomyosin family.	0.886
ACTA1	TPM4	ENSMFAP00000005196	ENSMFAP00000030582	Actin alpha 1, skeletal muscle.	Uncharacterized protein; Belongs to the tropomyosin family.	0.536
ACTA1	TPM4-2	ENSMFAP00000005196	ENSMFAP00000012033	Actin alpha 1, skeletal muscle.	Uncharacterized protein; Belongs to the tropomyosin family.	0.536
ACTN1	ACTA1	ENSMFAP00000034127	ENSMFAP00000005196	Alpha-actinin-1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (By similarity).	Actin alpha 1, skeletal muscle.	0.427

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