STRINGSTRING
PGRMC2 PGRMC2 ESR1 ESR1 NR2E3 NR2E3 ESRRA ESRRA ENSMFAP00000021707 ENSMFAP00000021707 HNF4A HNF4A PPARA PPARA PAQR7 PAQR7 ESRRG ESRRG PAQR8 PAQR8 ESRRB ESRRB NR3C2 NR3C2 RXRG RXRG NR4A3 NR4A3 NR2E1 NR2E1 NR3C1 NR3C1 ABHD2 ABHD2 RXRA RXRA PGR PGR ESR2 ESR2 PPARD PPARD RXRB RXRB NR1D1 NR1D1 GPER1 GPER1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PGRMC2Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family. (247 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
NR2E3Nuclear receptor subfamily 2 group E member 3. (462 aa)
ESRRAEstrogen related receptor alpha. (422 aa)
ENSMFAP00000021707Nuclear receptor domain-containing protein. (255 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (474 aa)
PPARAPeroxisome proliferator activated receptor alpha. (467 aa)
PAQR7Progestin and adipoQ receptor family member 7. (346 aa)
ESRRGEstrogen related receptor gamma. (470 aa)
PAQR8Progestin and adipoQ receptor family member 8. (354 aa)
ESRRBEstrogen related receptor beta. (438 aa)
NR3C2Nuclear receptor subfamily 3 group C member 2. (988 aa)
RXRGRetinoid X receptor gamma. (463 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (637 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
NR3C1Nuclear receptor subfamily 3 group C member 1. (778 aa)
ABHD2Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] (452 aa)
RXRARetinoid X receptor alpha. (443 aa)
PGRProgesterone receptor. (936 aa)
ESR2Estrogen receptor 2. (530 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
RXRBRetinoid X receptor beta. (537 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (613 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (369 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.