STRINGSTRING
ENSMFAP00000039612 ENSMFAP00000039612 APLF APLF HMGA2 HMGA2 NTHL1 NTHL1 ENSMFAP00000016477 ENSMFAP00000016477 Q9GMN5_MACFA Q9GMN5_MACFA POLB POLB ENSMFAP00000014690 ENSMFAP00000014690 ENSMFAP00000013555 ENSMFAP00000013555 NEIL1 NEIL1 OGG1 OGG1 RPS3 RPS3 NEIL2 NEIL2 ENSMFAP00000010938 ENSMFAP00000010938 HMGA1 HMGA1 APEX1 APEX1 NEIL3 NEIL3 APEX2 APEX2 ENSMFAP00000004486 ENSMFAP00000004486 ALKBH1 ALKBH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMFAP00000039612Uncharacterized protein. (175 aa)
APLFAprataxin and PNKP like factor. (512 aa)
HMGA2High mobility group AT-hook 2. (147 aa)
NTHL1Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (293 aa)
ENSMFAP00000016477Uncharacterized protein. (137 aa)
Q9GMN5_MACFAUncharacterized protein. (83 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa)
ENSMFAP00000014690Uncharacterized protein. (107 aa)
ENSMFAP00000013555Uncharacterized protein. (86 aa)
NEIL1Nei like DNA glycosylase 1. (390 aa)
OGG18-oxoguanine DNA glycosylase. (387 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
NEIL2Nei like DNA glycosylase 2. (319 aa)
ENSMFAP00000010938Uncharacterized protein. (107 aa)
HMGA1Uncharacterized protein. (201 aa)
APEX1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (324 aa)
NEIL3Nei like DNA glycosylase 3. (602 aa)
APEX2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (518 aa)
ENSMFAP00000004486Uncharacterized protein. (144 aa)
ALKBH1AlkB homolog 1, histone H2A dioxygenase. (389 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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