STRINGSTRING
CACNG1 CACNG1 GRM3 GRM3 CRISP1 CRISP1 CALM3 CALM3 STX1A STX1A CACNG7 CACNG7 G7PC42_MACFA G7PC42_MACFA TSPAN31 TSPAN31 PRKCB PRKCB CABP1 CABP1 MCUB MCUB NRXN3 NRXN3 RRAD RRAD REM2 REM2 CACNG8 CACNG8 CACNG6 CACNG6 CACNG4 CACNG4 STIMATE STIMATE TNNI3 TNNI3 CACNB3 CACNB3 PRKG1 PRKG1 REM1 REM1 ITPR1 ITPR1 CRISP2 CRISP2 NRXN2 NRXN2 CABP2 CABP2 FKBP1B FKBP1B TSPAN13 TSPAN13 CALM2 CALM2 CABP5 CABP5 CRISP3 CRISP3 MUSTN1 MUSTN1 CABP4 CABP4 NRXN1 NRXN1 CAV3 CAV3 GRM2 GRM2 ENSMFAP00000040719 ENSMFAP00000040719 AMBP AMBP YWHAE YWHAE ENSMFAP00000042187 ENSMFAP00000042187 SLC30A1 SLC30A1 HPCAL4 HPCAL4 STIM2 STIM2 STIM1 STIM1 CALM1 CALM1 PACSIN3 PACSIN3 PHPT1 PHPT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa)
GRM3Metabotropic glutamate receptor 3; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity (By similarity). (879 aa)
CRISP1Cysteine rich secretory protein 1; Belongs to the CRISP family. (249 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (288 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
G7PC42_MACFAUncharacterized protein; Belongs to the calmodulin family. (149 aa)
TSPAN31Tetraspanin 31; Belongs to the tetraspanin (TM4SF) family. (214 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (645 aa)
CABP1Uncharacterized protein. (302 aa)
MCUBMitochondrial calcium uniporter dominant negative beta subunit. (336 aa)
NRXN3Neurexin 3. (1664 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
REM2GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (340 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (320 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (261 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
STIMATEUncharacterized protein. (294 aa)
TNNI3Troponin I3, cardiac type. (210 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (484 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
CRISP2ShKT domain-containing protein; Belongs to the CRISP family. (278 aa)
NRXN2Neurexin 2. (1713 aa)
CABP2Calcium binding protein 2. (220 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
TSPAN13Tetraspanin 13; Belongs to the tetraspanin (TM4SF) family. (210 aa)
CALM2Calmodulin 2. (149 aa)
CABP5Calcium binding protein 5. (168 aa)
CRISP3Cysteine rich secretory protein 3; Belongs to the CRISP family. (245 aa)
MUSTN1Uncharacterized protein. (87 aa)
CABP4Calcium binding protein 4. (275 aa)
NRXN1Neurexin 1. (1507 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
GRM2Glutamate metabotropic receptor 2. (872 aa)
ENSMFAP0000004071914_3_3 domain-containing protein; Belongs to the 14-3-3 family. (217 aa)
AMBPAlpha-1-microglobulin/bikunin precursor. (352 aa)
YWHAE14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (256 aa)
ENSMFAP00000042187Uncharacterized protein; Belongs to the calmodulin family. (128 aa)
SLC30A1Zinc transporter 1; May be involved in zinc transport out of the cell. (505 aa)
HPCAL4Hippocalcin like 4. (191 aa)
STIM2Stromal interaction molecule 2. (840 aa)
STIM1Stromal interaction molecule 1. (770 aa)
CALM1Calmodulin 1. (149 aa)
PACSIN3Protein kinase C and casein kinase substrate in neurons 3. (424 aa)
PHPT1Phosphohistidine phosphatase 1. (125 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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