STRINGSTRING
DLST DLST ADHFE1 ADHFE1 KYAT3 KYAT3 ENSMFAP00000010941 ENSMFAP00000010941 GOT2 GOT2 OGDHL OGDHL GPT2 GPT2 L2HGDH L2HGDH D2HGDH D2HGDH MRPS36 MRPS36 TAT TAT AADAT AADAT IDH2 IDH2 OGDH OGDH ENSMFAP00000020437 ENSMFAP00000020437 PHYH PHYH ENSMFAP00000033177 ENSMFAP00000033177 IDH1 IDH1 LOC102121346 LOC102121346 GOT1 GOT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DLSTDihydrolipoamide S-succinyltransferase. (454 aa)
ADHFE1Fe-ADH domain-containing protein. (467 aa)
KYAT3Aminotran_1_2 domain-containing protein. (454 aa)
ENSMFAP00000010941Uncharacterized protein. (103 aa)
GOT2Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity). (430 aa)
OGDHLOxoglutarate dehydrogenase like. (1010 aa)
GPT2Glutamic--pyruvic transaminase 2. (599 aa)
L2HGDHL-2-hydroxyglutarate dehydrogenase. (463 aa)
D2HGDHD-2-hydroxyglutarate dehydrogenase. (517 aa)
MRPS36Uncharacterized protein. (103 aa)
TATTyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (454 aa)
AADATAminoadipate aminotransferase. (425 aa)
IDH2Isocitrate dehydrogenase [NADP], mitochondrial; Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex (By similarity); Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
OGDH2-oxoglutarate dehydrogenase, mitochondrial; 2-oxoglutarate dehydrogenase (E1) component of the 2- oxoglutarate dehydrogenase complex, which mediates the decarboxylation of alpha-ketoglutarate. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl- Co [...] (1038 aa)
ENSMFAP00000020437Aspartate aminotransferase. (385 aa)
PHYHPhytanoyl-CoA 2-hydroxylase. (345 aa)
ENSMFAP00000033177Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (430 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (417 aa)
LOC102121346Uncharacterized protein. (102 aa)
GOT1Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] (413 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.