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EIF4G1 | Eukaryotic translation initiation factor 4 gamma 1. (1605 aa) | ||||
ENSMFAP00000035641 | RRM domain-containing protein. (539 aa) | ||||
LOC102143207 | Uncharacterized protein. (206 aa) | ||||
CSDE1 | Cold shock domain containing E1. (844 aa) | ||||
DHX29 | ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1367 aa) | ||||
ENSMFAP00000034212 | RWD domain-containing protein. (293 aa) | ||||
ENSMFAP00000033189 | Uncharacterized protein. (192 aa) | ||||
EIF4B | RRM domain-containing protein. (612 aa) | ||||
IMPACT | RWD domain-containing protein. (320 aa) | ||||
PPP1R15A | Protein phosphatase 1 regulatory subunit 15A. (675 aa) | ||||
UHMK1 | U2AF homology motif kinase 1. (419 aa) | ||||
EIF2B5 | Eukaryotic translation initiation factor 2B subunit epsilon. (721 aa) | ||||
HSPB1 | SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (205 aa) | ||||
ENSMFAP00000027163 | RRM domain-containing protein. (594 aa) | ||||
MTIF2 | Mitochondrial translational initiation factor 2. (727 aa) | ||||
NCK1 | Cytoplasmic protein. (377 aa) | ||||
ENSMFAP00000025493 | Uncharacterized protein. (274 aa) | ||||
ENSMFAP00000025396 | Uncharacterized protein. (274 aa) | ||||
C8orf88 | Chromosome 8 open reading frame 88. (117 aa) | ||||
EIF2B2 | Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa) | ||||
ENSMFAP00000023932 | Uncharacterized protein. (256 aa) | ||||
RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) | ||||
PAIP1 | Poly(A) binding protein interacting protein 1. (480 aa) | ||||
METTL3 | Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa) | ||||
ENSMFAP00000022878 | Uncharacterized protein. (180 aa) | ||||
ENSMFAP00000022314 | Uncharacterized protein. (200 aa) | ||||
EIF4G3 | Eukaryotic translation initiation factor 4 gamma 3. (1740 aa) | ||||
EIF2AK4 | Eukaryotic translation initiation factor 2 alpha kinase 4. (1248 aa) | ||||
NCK2 | Cytoplasmic protein. (382 aa) | ||||
EIF5 | Eukaryotic translation initiation factor 5. (431 aa) | ||||
TPR | Translocated promoter region, nuclear basket protein. (2439 aa) | ||||
PAIP2 | Poly(A) binding protein interacting protein 2. (126 aa) | ||||
EIF4H | RRM domain-containing protein. (248 aa) | ||||
POLR2D | RNA polymerase II subunit D. (142 aa) | ||||
EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa) | ||||
LARP1 | La ribonucleoprotein domain family member 1. (1021 aa) | ||||
RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (487 aa) | ||||
ENSMFAP00000016028 | Uncharacterized protein. (232 aa) | ||||
BOLL | Protein boule-like; Probable RNA-binding protein, which may be required during spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation (By similarity). (320 aa) | ||||
NCBP1 | Nuclear cap binding protein subunit 1. (790 aa) | ||||
EIF2AK2 | Eukaryotic translation initiation factor 2 alpha kinase 2. (554 aa) | ||||
AGO2 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (881 aa) | ||||
PAIP2B | Poly(A) binding protein interacting protein 2B. (123 aa) | ||||
YTHDF2 | YTH domain-containing family protein 2; Specifically recognizes and binds N6-methyladenosine (m6A)- containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing. Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in mRNA degradation. Required maternally to regulate oocyte maturation: probably acts by binding to m6A-containing mRNAs, thereby regulating maternal transcript dosage during oocyte maturation, which is essential for the competence o [...] (593 aa) | ||||
BZW1 | Basic leucine zipper and W2 domains 1. (451 aa) | ||||
KLHL25 | Kelch like family member 25. (589 aa) | ||||
DDX3X | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (733 aa) | ||||
EIF3H | Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (366 aa) | ||||
NPM1 | Uncharacterized protein. (305 aa) | ||||
FMR1 | Fragile X mental retardation 1. (632 aa) | ||||
RPL13A | 60S ribosomal protein L13a; Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppres [...] (203 aa) | ||||
ENSMFAP00000008653 | Uncharacterized protein. (311 aa) | ||||
KHDRBS1 | KH domain-containing protein. (443 aa) | ||||
EIF4EBP2 | Eukaryotic translation initiation factor 4E binding protein 2. (120 aa) | ||||
HABP4 | Hyaluronan binding protein 4. (413 aa) | ||||
RBM4B | RNA-binding protein 4; RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5'-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs. Required for the translational activation [...] (359 aa) | ||||
POLR2G | S1 domain-containing protein. (234 aa) | ||||
ENSMFAP00000007021 | Uncharacterized protein. (195 aa) | ||||
YTHDF1 | YTH N6-methyladenosine RNA binding protein 1. (559 aa) | ||||
ENSMFAP00000006551 | Uncharacterized protein. (229 aa) | ||||
ENSMFAP00000006058 | Uncharacterized protein. (305 aa) | ||||
DAZL | Deleted in azoospermia-like; RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity). (315 aa) | ||||
PML | Promyelocytic leukemia. (882 aa) | ||||
ENSMFAP00000005021 | Uncharacterized protein. (109 aa) | ||||
PPP1CA | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa) | ||||
ALKBH1 | AlkB homolog 1, histone H2A dioxygenase. (389 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) | ||||
ENSMFAP00000002634 | Uncharacterized protein. (284 aa) | ||||
ENSMFAP00000001669 | Uncharacterized protein. (268 aa) | ||||
ENSMFAP00000001598 | SUI1 domain-containing protein. (115 aa) | ||||
ENSMFAP00000001570 | GOLD domain-containing protein. (188 aa) | ||||
MIF4GD | MIF4G domain containing. (262 aa) | ||||
EIF4G2 | Eukaryotic translation initiation factor 4 gamma 2. (925 aa) | ||||
TMED2 | GOLD domain-containing protein. (208 aa) | ||||
ENSMFAP00000000767 | Uncharacterized protein. (208 aa) | ||||
ATF4 | Activating transcription factor 4. (351 aa) | ||||
EIF4EBP1 | Eukaryotic translation initiation factor 4E binding protein 1. (118 aa) | ||||
ENSMFAP00000045074 | Uncharacterized protein. (128 aa) | ||||
EIF2AK1 | Eukaryotic translation initiation factor 2-alpha kinase 1; Inhibits protein synthesis at the translation initiation level, in response to various stress conditions, including oxidative stress, heme deficiency, osmotic shock and heat shock. Exerts its function through the phosphorylation of EIF2S1 at 'Ser-48' and 'Ser- 51', thus preventing its recycling. Binds hemin forming a 1:1 complex through a cysteine thiolate and histidine nitrogenous coordination. This binding occurs with moderate affinity, allowing it to sense the heme concentration within the cell. Thanks to this unique heme-se [...] (631 aa) | ||||
EIF1 | Eukaryotic translation initiation factor 1. (113 aa) | ||||
EIF3K | Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (218 aa) | ||||
PPP1R15B | Protein phosphatase 1 regulatory subunit 15B. (710 aa) | ||||
BZW2 | Basic leucine zipper and W2 domain-containing protein 2; May be involved in neuronal differentiation. (519 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) | ||||
LOC102123956 | ANK_REP_REGION domain-containing protein. (2626 aa) | ||||
BANK1 | B cell scaffold protein with ankyrin repeats 1. (786 aa) | ||||
EIF3B | Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (775 aa) | ||||
ENSMFAP00000039768 | SUI1 domain-containing protein. (118 aa) | ||||
ENSMFAP00000039100 | Uncharacterized protein. (329 aa) | ||||
ENSMFAP00000037361 | Uncharacterized protein. (111 aa) | ||||
CTIF | Cap binding complex dependent translation initiation factor. (600 aa) | ||||
EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) | ||||
ENSMFAP00000036680 | RWD domain-containing protein. (136 aa) | ||||
ENSMFAP00000036291 | RRM domain-containing protein. (241 aa) | ||||
DNAJC3 | DnaJ heat shock protein family (Hsp40) member C3. (504 aa) |