STRINGSTRING
TMED5 TMED5 SEC16B SEC16B TMED2 TMED2 HUWE1 HUWE1 DYNC2H1 DYNC2H1 ENSMFAP00000001570 ENSMFAP00000001570 SYNE1 SYNE1 LRRK2 LRRK2 RAB1B RAB1B ENSMFAP00000003274 ENSMFAP00000003274 CLASP2 CLASP2 GOLGA5 GOLGA5 ENSMFAP00000004425 ENSMFAP00000004425 PLK5 PLK5 FAM174B FAM174B FHDC1 FHDC1 LYSMD4 LYSMD4 CIT CIT ATP8B1 ATP8B1 LMAN1L LMAN1L KIFC3 KIFC3 COG2 COG2 FBXW8 FBXW8 TRIP11 TRIP11 PRMT5 PRMT5 LYSMD2 LYSMD2 GCC2 GCC2 HOOK1 HOOK1 VRK1 VRK1 ATP8B4 ATP8B4 LOC102122160 LOC102122160 ZW10 ZW10 ENSMFAP00000010412 ENSMFAP00000010412 ENSMFAP00000010473 ENSMFAP00000010473 TBC1D20 TBC1D20 UBXN2B UBXN2B ENSMFAP00000011889 ENSMFAP00000011889 COG1 COG1 LOC102142638 LOC102142638 ENSMFAP00000012314 ENSMFAP00000012314 ATP8B2 ATP8B2 RAB2B RAB2B ZNF501 ZNF501 ENSMFAP00000013631 ENSMFAP00000013631 DNAJC28 DNAJC28 ATP8B3 ATP8B3 ENSMFAP00000014556 ENSMFAP00000014556 ARFGEF1 ARFGEF1 COG6 COG6 TTC38 TTC38 TJAP1 TJAP1 GOLGB1 GOLGB1 ENSMFAP00000016180 ENSMFAP00000016180 YIPF4 YIPF4 VCPIP1 VCPIP1 SEC16A SEC16A ENSMFAP00000017022 ENSMFAP00000017022 ENSMFAP00000017062 ENSMFAP00000017062 ENSMFAP00000017296 ENSMFAP00000017296 VAMP4 VAMP4 BET1 BET1 DYM DYM RAB6B RAB6B TMED6 TMED6 VTI1A VTI1A STX6 STX6 VTI1B VTI1B PI4K2B PI4K2B COG3 COG3 RAB30 RAB30 ENSMFAP00000020841 ENSMFAP00000020841 HIKESHI HIKESHI RAB8A RAB8A ARL1 ARL1 ATL3 ATL3 TMED4 TMED4 GAK GAK ZFP69B ZFP69B CLASP1 CLASP1 NSFL1C NSFL1C PLEKHM2 PLEKHM2 USP6NL USP6NL FAM71C FAM71C STK25 STK25 ENSMFAP00000025899 ENSMFAP00000025899 LMAN2 LMAN2 GOLGA2 GOLGA2 LMAN1 LMAN1 TMED7 TMED7 GOLGA6C GOLGA6C PDCD10 PDCD10 GOLPH3 GOLPH3 ENSMFAP00000027946 ENSMFAP00000027946 TMED9 TMED9 SURF4 SURF4 GORASP2 GORASP2 TRAPPC12 TRAPPC12 OPTN OPTN ENSMFAP00000028876 ENSMFAP00000028876 YIPF7 YIPF7 BCAS3 BCAS3 STX17 STX17 GOLPH3L GOLPH3L BLZF1 BLZF1 SEC23IP SEC23IP HTT HTT GBF1 GBF1 ARHGEF7 ARHGEF7 ENSMFAP00000033007 ENSMFAP00000033007 MYO18A MYO18A PI4K2A PI4K2A STX5 STX5 TANGO2 TANGO2 ENSMFAP00000035948 ENSMFAP00000035948 FAM71B FAM71B STX16 STX16 OBSL1 OBSL1 LYSMD3 LYSMD3 VPS13B VPS13B ENSMFAP00000037037 ENSMFAP00000037037 RAB2A RAB2A TMED3 TMED3 ATL2 ATL2 USO1 USO1 VPS51 VPS51 ENSMFAP00000038262 ENSMFAP00000038262 UBXN2A UBXN2A ENSMFAP00000038678 ENSMFAP00000038678 SMIM7 SMIM7 ENSMFAP00000039539 ENSMFAP00000039539 BAG5 BAG5 CUL7 CUL7 RAB1A RAB1A GOLGA6A GOLGA6A COG5 COG5 ARHGAP21 ARHGAP21 RAB29 RAB29 PRKD1 PRKD1 RAB43 RAB43 HACE1 HACE1 SPTBN5 SPTBN5 COG7 COG7 TRAPPC8 TRAPPC8 PLK3 PLK3 CDK1 CDK1 ENSMFAP00000044639 ENSMFAP00000044639 TRAPPC11 TRAPPC11 LOC107127874 LOC107127874 ENSMFAP00000044945 ENSMFAP00000044945 GORASP1 GORASP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TMED5Transmembrane p24 trafficking protein 5. (229 aa)
SEC16BProtein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (1061 aa)
TMED2GOLD domain-containing protein. (208 aa)
HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4390 aa)
DYNC2H1Dynein cytoplasmic 2 heavy chain 1. (4314 aa)
ENSMFAP00000001570GOLD domain-containing protein. (188 aa)
SYNE1Spectrin repeat containing nuclear envelope protein 1. (8797 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
RAB1BRas-related protein Rab-1B; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum (By similarity). Regulates [...] (214 aa)
ENSMFAP00000003274Uncharacterized protein. (594 aa)
CLASP2Uncharacterized protein. (1514 aa)
GOLGA5Golgin A5. (731 aa)
ENSMFAP00000004425Uncharacterized protein. (235 aa)
PLK5Polo like kinase 5. (304 aa)
FAM174BFamily with sequence similarity 174 member B. (157 aa)
FHDC1FH2 domain containing 1. (1149 aa)
LYSMD4LysM domain containing 4. (296 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2069 aa)
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1251 aa)
LMAN1LLectin, mannose binding 1 like. (508 aa)
KIFC3Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (989 aa)
COG2Component of oligomeric golgi complex 2. (738 aa)
FBXW8F-box and WD repeat domain containing 8. (598 aa)
TRIP11Thyroid hormone receptor interactor 11. (1981 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H and may regulate its transcriptional elongation properties (By similarity). Mono- and dimethylates arginine resi [...] (620 aa)
LYSMD2LysM domain containing 2. (124 aa)
GCC2GRIP and coiled-coil domain containing 2. (1686 aa)
HOOK1Hook microtubule tethering protein 1. (728 aa)
VRK1VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily. (396 aa)
ATP8B4Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1191 aa)
LOC102122160Uncharacterized protein. (246 aa)
ZW10Zw10 kinetochore protein. (778 aa)
ENSMFAP00000010412Uncharacterized protein. (119 aa)
ENSMFAP00000010473Uncharacterized protein. (212 aa)
TBC1D20TBC1 domain family member 20. (407 aa)
UBXN2BUBX domain protein 2B. (331 aa)
ENSMFAP00000011889Uncharacterized protein. (154 aa)
COG1Component of oligomeric golgi complex 1. (980 aa)
LOC102142638Protein kinase domain-containing protein. (297 aa)
ENSMFAP00000012314Uncharacterized protein. (212 aa)
ATP8B2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1223 aa)
RAB2BRAB2B, member RAS oncogene family. (216 aa)
ZNF501Zinc finger protein 501. (271 aa)
ENSMFAP00000013631Uncharacterized protein. (518 aa)
DNAJC28DnaJ heat shock protein family (Hsp40) member C28. (388 aa)
ATP8B3Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1307 aa)
ENSMFAP00000014556V-SNARE domain-containing protein. (198 aa)
ARFGEF1ADP ribosylation factor guanine nucleotide exchange factor 1. (1849 aa)
COG6Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. (657 aa)
TTC38Tetratricopeptide repeat domain 38. (469 aa)
TJAP1Tight junction associated protein 1. (541 aa)
GOLGB1Golgin B1. (3268 aa)
ENSMFAP00000016180Uncharacterized protein. (589 aa)
YIPF4Protein YIPF. (244 aa)
VCPIP1Valosin containing protein interacting protein 1. (1221 aa)
SEC16AProtein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2328 aa)
ENSMFAP00000017022Uncharacterized protein. (210 aa)
ENSMFAP00000017062L-type lectin-like domain-containing protein. (124 aa)
ENSMFAP00000017296Uncharacterized protein. (633 aa)
VAMP4Vesicle associated membrane protein 4. (141 aa)
BET1Bet1 golgi vesicular membrane trafficking protein. (118 aa)
DYMDymeclin. (724 aa)
RAB6BRAB6B, member RAS oncogene family. (208 aa)
TMED6GOLD domain-containing protein. (240 aa)
VTI1AVesicle transport through interaction with t-SNAREs 1A. (217 aa)
STX6Syntaxin 6; Belongs to the syntaxin family. (255 aa)
VTI1BVesicle transport through interaction with t-SNAREs 1B. (232 aa)
PI4K2BPhosphatidylinositol 4-kinase type 2 beta. (481 aa)
COG3Component of oligomeric golgi complex 3. (828 aa)
RAB30RAB30, member RAS oncogene family. (203 aa)
ENSMFAP00000020841Uncharacterized protein. (615 aa)
HIKESHIHeat shock protein nuclear import factor hikeshi. (197 aa)
RAB8ARas-related protein Rab-8A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in polarized vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes t [...] (207 aa)
ARL1ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
ATL3Atlastin GTPase 3. (544 aa)
TMED4Transmembrane p24 trafficking protein 4. (227 aa)
GAKCyclin G associated kinase. (1311 aa)
ZFP69BZFP69 zinc finger protein B. (534 aa)
CLASP1Cytoplasmic linker associated protein 1. (1533 aa)
NSFL1CNSFL1 cofactor. (372 aa)
PLEKHM2Pleckstrin homology and RUN domain containing M2. (1005 aa)
USP6NLUSP6 N-terminal like. (851 aa)
FAM71CProtein FAM71C; Belongs to the FAM71 family. (241 aa)
STK25Serine/threonine kinase 25. (426 aa)
ENSMFAP00000025899Uncharacterized protein. (316 aa)
LMAN2Lectin, mannose binding 2. (321 aa)
GOLGA2Golgin A2. (1005 aa)
LMAN1Lectin, mannose binding 1. (510 aa)
TMED7Transmembrane p24 trafficking protein 7. (224 aa)
GOLGA6CUncharacterized protein. (643 aa)
PDCD10Programmed cell death protein 10. (212 aa)
GOLPH3Golgi phosphoprotein 3. (298 aa)
ENSMFAP00000027946Uncharacterized protein. (577 aa)
TMED9GOLD domain-containing protein. (235 aa)
SURF4Surfeit 4. (269 aa)
GORASP2Golgi reassembly stacking protein 2. (452 aa)
TRAPPC12Trafficking protein particle complex 12. (740 aa)
OPTNOptineurin; Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation. Negatively regulates the induction of IFNB in response to RNA virus infection. Plays a neuroprotective role in the eye and optic nerve. Probably part of the TNF-alpha signaling pathway that can shift the equilibrium toward induction of cell death. May act by regulating membrane trafficking and cellular morphogenesis via a complex th [...] (571 aa)
ENSMFAP00000028876Uncharacterized protein. (625 aa)
YIPF7Protein YIPF. (256 aa)
BCAS3BCAS3 microtubule associated cell migration factor. (922 aa)
STX17Syntaxin 17; Belongs to the syntaxin family. (302 aa)
GOLPH3LGolgi phosphoprotein 3 like. (285 aa)
BLZF1Basic leucine zipper nuclear factor 1. (404 aa)
SEC23IPSEC23 interacting protein. (1025 aa)
HTTHuntingtin. (3118 aa)
GBF1Golgi brefeldin A resistant guanine nucleotide exchange factor 1. (1859 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (862 aa)
ENSMFAP00000033007Uncharacterized protein. (737 aa)
MYO18AMyosin XVIIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2054 aa)
PI4K2APhosphatidylinositol 4-kinase type 2 alpha. (480 aa)
STX5Syntaxin 5; Belongs to the syntaxin family. (361 aa)
TANGO2Transport and golgi organization 2 homolog. (317 aa)
ENSMFAP00000035948Uncharacterized protein. (220 aa)
FAM71BFamily with sequence similarity 71 member B. (605 aa)
STX16Syntaxin 16; Belongs to the syntaxin family. (325 aa)
OBSL1Obscurin like 1. (1896 aa)
LYSMD3LysM domain containing 3. (306 aa)
VPS13BVacuolar protein sorting 13 homolog B. (4022 aa)
ENSMFAP00000037037Uncharacterized protein. (141 aa)
RAB2ARas-related protein Rab-2A; Required for protein transport from the endoplasmic reticulum to the Golgi complex. (212 aa)
TMED3Transmembrane p24 trafficking protein 3. (248 aa)
ATL2Atlastin-2; GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. (583 aa)
USO1USO1 vesicle transport factor. (973 aa)
VPS51VPS51 subunit of GARP complex. (808 aa)
ENSMFAP00000038262Uncharacterized protein. (89 aa)
UBXN2AUBX domain protein 2A. (260 aa)
ENSMFAP00000038678Uncharacterized protein. (632 aa)
SMIM7Small integral membrane protein 7. (139 aa)
ENSMFAP00000039539Uncharacterized protein. (695 aa)
BAG5BCL2 associated athanogene 5. (488 aa)
CUL7Cullin 7; Belongs to the cullin family. (1780 aa)
RAB1AUncharacterized protein. (217 aa)
GOLGA6AUncharacterized protein. (87 aa)
COG5Component of oligomeric golgi complex 5. (860 aa)
ARHGAP21Rho GTPase activating protein 21. (1958 aa)
RAB29RAB29, member RAS oncogene family. (203 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (920 aa)
RAB43RAB43, member RAS oncogene family. (212 aa)
HACE1HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1. (909 aa)
SPTBN5Spectrin beta, non-erythrocytic 5. (3672 aa)
COG7Component of oligomeric golgi complex 7. (770 aa)
TRAPPC8Trafficking protein particle complex 8. (1435 aa)
PLK3Serine/threonine-protein kinase PLK. (664 aa)
CDK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
ENSMFAP00000044639GOLD domain-containing protein. (215 aa)
TRAPPC11Trafficking protein particle complex 11. (1133 aa)
LOC107127874UN_NPL4 domain-containing protein. (130 aa)
ENSMFAP00000044945Uncharacterized protein. (199 aa)
GORASP1Golgi reassembly stacking protein 1. (440 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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