STRINGSTRING
SPRED1 SPRED1 PATZ1 PATZ1 SLIT2 SLIT2 TGFB1 TGFB1 RHOA RHOA TNF TNF SYNJ2BP SYNJ2BP TBXA2R TBXA2R PTPRM PTPRM ADAMTS9 ADAMTS9 MEOX2 MEOX2 ENSMFAP00000010473 ENSMFAP00000010473 AGTR2 AGTR2 ATP2B4 ATP2B4 NR2F2 NR2F2 MAP2K5 MAP2K5 SP100 SP100 DNAJA4 DNAJA4 GDF2 GDF2 ADGRB1 ADGRB1 VASH1 VASH1 HRG HRG CXCL13 CXCL13 APOH APOH THBS1 THBS1 MECP2 MECP2 KRIT1 KRIT1 KLF4 KLF4 GADD45A GADD45A RGCC RGCC ENSMFAP00000025660 ENSMFAP00000025660 SERPINF1 SERPINF1 CARD10 CARD10 STARD13 STARD13 ANGPT2 ANGPT2 MEF2C MEF2C PDCD10 PDCD10 ITGB1BP1 ITGB1BP1 ANGPT4 ANGPT4 MMRN2 MMRN2 DAB2IP DAB2IP DLL4 DLL4 JUP JUP DCN DCN BMP10 BMP10 ACVRL1 ACVRL1 SVBP SVBP STC1 STC1 NOTCH1 NOTCH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPRED1Sprouty related EVH1 domain containing 1. (444 aa)
PATZ1POZ/BTB and AT hook containing zinc finger 1. (687 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
RHOAUncharacterized protein. (141 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
SYNJ2BPSynaptojanin 2 binding protein. (145 aa)
TBXA2RThromboxane A2 receptor. (455 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1465 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1935 aa)
MEOX2Mesenchyme homeobox 2. (303 aa)
ENSMFAP00000010473Uncharacterized protein. (212 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
NR2F2Nuclear receptor subfamily 2 group F member 2. (414 aa)
MAP2K5Uncharacterized protein; Belongs to the protein kinase superfamily. (448 aa)
SP100SP100 nuclear antigen. (863 aa)
DNAJA4DnaJ heat shock protein family (Hsp40) member A4. (426 aa)
GDF2Growth differentiation factor 2. (429 aa)
ADGRB1Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1566 aa)
VASH1Vasohibin 1. (365 aa)
HRGHistidine rich glycoprotein. (525 aa)
CXCL13C-X-C motif chemokine. (109 aa)
APOHUncharacterized protein. (355 aa)
THBS1Thrombospondin 1. (1173 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)- containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
KRIT1Uncharacterized protein. (736 aa)
KLF4Testis cDNA clone: QtsA-19426, similar to human Kruppel-like factor 4 (gut) (KLF4). (479 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (165 aa)
RGCCRegulator of cell cycle. (137 aa)
ENSMFAP00000025660Uncharacterized protein. (342 aa)
SERPINF1SERPIN domain-containing protein; Belongs to the serpin family. (406 aa)
CARD10Caspase recruitment domain family member 10. (1050 aa)
STARD13StAR related lipid transfer domain containing 13. (1113 aa)
ANGPT2Angiopoietin 2. (496 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
PDCD10Programmed cell death protein 10. (212 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
ANGPT4Angiopoietin 4. (503 aa)
MMRN2Multimerin 2. (951 aa)
DAB2IPDAB2 interacting protein. (1153 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
JUPJunction plakoglobin. (745 aa)
DCNDecorin; May affect the rate of fibrils formation. (359 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
SVBPSmall vasohibin binding protein. (66 aa)
STC1Stanniocalcin 1. (247 aa)
NOTCH1Notch receptor 1. (2556 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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