STRINGSTRING
HMOX1 HMOX1 NOTCH1 NOTCH1 PPM1F PPM1F MAPRE2 MAPRE2 PTPN23 PTPN23 PLCG1 PLCG1 EMC10 EMC10 RREB1 RREB1 STC1 STC1 EPB41L5 EPB41L5 SCARB1 SCARB1 ABL1 ABL1 FLT4 FLT4 BMPER BMPER SOX9 SOX9 ADAM9 ADAM9 ALOX12 ALOX12 NRP2 NRP2 ADAM17 ADAM17 FOXP1 FOXP1 BSG BSG SVBP SVBP PRKD1 PRKD1 MTOR MTOR ITGB3 ITGB3 CCR6 CCR6 ENSMFAP00000042030 ENSMFAP00000042030 ACVRL1 ACVRL1 EPB41L4B EPB41L4B RHOJ RHOJ ENSMFAP00000041212 ENSMFAP00000041212 P2RX4 P2RX4 EFNA1 EFNA1 NFE2L2 NFE2L2 NF1 NF1 SIRT1 SIRT1 FBXW7 FBXW7 DOCK1 DOCK1 PRKD2 PRKD2 SEMA5A SEMA5A BMP10 BMP10 SPARC SPARC GATA2 GATA2 FGF18 FGF18 MAP2K3 MAP2K3 FGFR1 FGFR1 DCN DCN ARSI ARSI AAMP AAMP GLIPR2 GLIPR2 JUP JUP WNT5A WNT5A FOXC2 FOXC2 ATP5F1B ATP5F1B ENSMFAP00000035291 ENSMFAP00000035291 ARSB ARSB TGFBR2 TGFBR2 SMOC2 SMOC2 PTK2B PTK2B VEGFC VEGFC EGF EGF FGF10 FGF10 PTEN PTEN PRKCE PRKCE ANXA3 ANXA3 RTN4 RTN4 HYAL1 HYAL1 RIN2 RIN2 ENPP2 ENPP2 CEACAM1 CEACAM1 NUS1 NUS1 DLL4 DLL4 GATA3 GATA3 PLCG2 PLCG2 DAB2IP DAB2IP MMRN2 MMRN2 IRS2 IRS2 ANXA1 ANXA1 ENSMFAP00000030346 ENSMFAP00000030346 PROX1 PROX1 BCAS3 BCAS3 FGF7 FGF7 ANGPT4 ANGPT4 ANGPT1 ANGPT1 FGF4 FGF4 ITGB1BP1 ITGB1BP1 GPLD1 GPLD1 HSPB1 HSPB1 SP1 SP1 SRPX2 SRPX2 TSTA3 TSTA3 EPHA2 EPHA2 PTN PTN TEK TEK PDCD10 PDCD10 MEF2C MEF2C WNT7A WNT7A ENSMFAP00000026709 ENSMFAP00000026709 ANGPT2 ANGPT2 STARD13 STARD13 CARD10 CARD10 FGF16 FGF16 SERPINF1 SERPINF1 LGMN LGMN ENSMFAP00000025660 ENSMFAP00000025660 HDAC7 HDAC7 PTPRG PTPRG HDAC6 HDAC6 VEGFA VEGFA PFN2 PFN2 CORO1C CORO1C IQSEC1 IQSEC1 CLASP1 CLASP1 IFNG IFNG HBEGF HBEGF TACR1 TACR1 ROCK2 ROCK2 ITGA3 ITGA3 MARVELD3 MARVELD3 VIL1 VIL1 KDR KDR RGCC RGCC GADD45A GADD45A ENSMFAP00000022686 ENSMFAP00000022686 ADGRA2 ADGRA2 MAP4K4 MAP4K4 KLF4 KLF4 DUSP10 DUSP10 FBXW9 FBXW9 MCC MCC MAP3K3 MAP3K3 AKT3 AKT3 PIK3CG PIK3CG KRIT1 KRIT1 MECP2 MECP2 THBS1 THBS1 NRP1 NRP1 CD40 CD40 HAS2 HAS2 APOH APOH CXCL13 CXCL13 HRG HRG ZC3H12A ZC3H12A PTPRR PTPRR HIF1A HIF1A AMOT AMOT VASH1 VASH1 ADGRB1 ADGRB1 BMPR2 BMPR2 SRC SRC GDF2 GDF2 SPRED1 SPRED1 AKT1 AKT1 ITGA2 ITGA2 PDGFB PDGFB FGF1 FGF1 ATOH8 ATOH8 MMP9 MMP9 DNAJA4 DNAJA4 SP100 SP100 PDPK1 PDPK1 MAP2K5 MAP2K5 RHOB RHOB FUT1 FUT1 ZNF580 ZNF580 RRAS RRAS PTGS2 PTGS2 MET MET PRKCA PRKCA PLPP3 PLPP3 STAT5A STAT5A ARSJ ARSJ NR2F2 NR2F2 ATP2B4 ATP2B4 HDAC9 HDAC9 TACSTD2 TACSTD2 AGTR2 AGTR2 AGT AGT ENSMFAP00000010473 ENSMFAP00000010473 PLK2 PLK2 FGF2 FGF2 EVL EVL BMP4 BMP4 MEOX2 MEOX2 ADAMTS9 ADAMTS9 PIK3CB PIK3CB PTPRM PTPRM TDGF1 TDGF1 TGFB2 TGFB2 CIB1 CIB1 TBXA2R TBXA2R ETS1 ETS1 NOS3 NOS3 NR2E1 NR2E1 CAPN7 CAPN7 DOCK5 DOCK5 ATP5F1A ATP5F1A PTK2 PTK2 CLASP2 CLASP2 ARF6 ARF6 JCAD JCAD SYNJ2BP SYNJ2BP ENSMFAP00000002824 ENSMFAP00000002824 TNF TNF CTSH CTSH RHOA RHOA RAB25 RAB25 MACF1 MACF1 GLUL GLUL SEMA4A SEMA4A CCBE1 CCBE1 BCAR1 BCAR1 SASH1 SASH1 CALR CALR GRN GRN PIK3CD PIK3CD TGFB1 TGFB1 SLIT2 SLIT2 PATZ1 PATZ1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HMOX1Uncharacterized protein. (288 aa)
NOTCH1Notch receptor 1. (2556 aa)
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (455 aa)
MAPRE2Microtubule associated protein RP/EB family member 2. (327 aa)
PTPN23Protein tyrosine phosphatase non-receptor type 23. (1633 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
EMC10ER membrane protein complex subunit 10. (335 aa)
RREB1Ras responsive element binding protein 1. (1744 aa)
STC1Stanniocalcin 1. (247 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (733 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase. (901 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1362 aa)
BMPERBMP binding endothelial regulator. (685 aa)
SOX9SRY-box transcription factor 9. (509 aa)
ADAM9ADAM metallopeptidase domain 9. (819 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S type. (663 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (930 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
FOXP1Forkhead box P1. (693 aa)
BSGBasigin (Ok blood group). (366 aa)
SVBPSmall vasohibin binding protein. (66 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (920 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (379 aa)
ENSMFAP00000042030Profilin; Belongs to the profilin family. (132 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
EPB41L4BErythrocyte membrane protein band 4.1 like 4B. (831 aa)
RHOJUncharacterized protein. (214 aa)
ENSMFAP00000041212Uncharacterized protein; Belongs to the glutamine synthetase family. (196 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
NF1Neurofibromin 1. (2849 aa)
SIRT1Sirtuin 1. (743 aa)
FBXW7F-box and WD repeat domain containing 7. (707 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1886 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
SEMA5ASemaphorin 5A. (1074 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
SPARCSecreted protein acidic and cysteine rich. (303 aa)
GATA2GATA binding protein 2. (480 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (394 aa)
FGFR1Fibroblast growth factor receptor. (820 aa)
DCNDecorin; May affect the rate of fibrils formation. (359 aa)
ARSIArylsulfatase family member I. (569 aa)
AAMPAngio associated migratory cell protein. (454 aa)
GLIPR2Testis cDNA clone: QtsA-11864, similar to human chromosome 9 open reading frame 19 (C9orf19); Belongs to the CRISP family. (165 aa)
JUPJunction plakoglobin. (745 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
FOXC2Forkhead box C2. (487 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (529 aa)
ENSMFAP00000035291Uncharacterized protein. (159 aa)
ARSBArylsulfatase B. (534 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
SMOC2SPARC related modular calcium binding 2. (330 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (420 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
ANXA3Annexin. (323 aa)
RTN4Reticulon. (1193 aa)
HYAL1Hyaluronidase. (435 aa)
RIN2Ras and Rab interactor 2. (895 aa)
ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase 2. (915 aa)
CEACAM1Uncharacterized protein. (525 aa)
NUS1NUS1 dehydrodolichyl diphosphate synthase subunit. (293 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
GATA3GATA binding protein 3. (444 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
DAB2IPDAB2 interacting protein. (1153 aa)
MMRN2Multimerin 2. (951 aa)
IRS2Insulin receptor substrate 2. (1279 aa)
ANXA1Annexin. (346 aa)
ENSMFAP00000030346ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (411 aa)
PROX1Prospero homeobox 1. (737 aa)
BCAS3BCAS3 microtubule associated cell migration factor. (922 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
ANGPT4Angiopoietin 4. (503 aa)
ANGPT1Angiopoietin 1. (498 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (841 aa)
HSPB1SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (205 aa)
SP1Sp1 transcription factor. (786 aa)
SRPX2Sushi repeat containing protein X-linked 2. (465 aa)
TSTA3Tissue specific transplantation antigen P35B. (321 aa)
EPHA2Ephrin type-A receptor 2; Receptor tyrosine kinase which binds promiscuously membrane- bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin- A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DS [...] (1036 aa)
PTNPleiotrophin. (172 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
PDCD10Programmed cell death protein 10. (212 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
WNT7AProtein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal [...] (349 aa)
ENSMFAP00000026709CFC domain-containing protein. (170 aa)
ANGPT2Angiopoietin 2. (496 aa)
STARD13StAR related lipid transfer domain containing 13. (1113 aa)
CARD10Caspase recruitment domain family member 10. (1050 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
SERPINF1SERPIN domain-containing protein; Belongs to the serpin family. (406 aa)
LGMNLegumain; Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system (By similarity). (433 aa)
ENSMFAP00000025660Uncharacterized protein. (342 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1008 aa)
PTPRGProtein tyrosine phosphatase receptor type G. (1445 aa)
HDAC6Histone deacetylase 6. (1215 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (409 aa)
PFN2Profilin-2; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity). (188 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (527 aa)
IQSEC1IQ motif and Sec7 domain 1. (1115 aa)
CLASP1Cytoplasmic linker associated protein 1. (1533 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1064 aa)
MARVELD3MARVEL domain containing 3. (410 aa)
VIL1Villin 1. (830 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
RGCCRegulator of cell cycle. (137 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (165 aa)
ENSMFAP00000022686Uncharacterized protein. (440 aa)
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1340 aa)
MAP4K4Mitogen-activated protein kinase kinase kinase kinase 4. (1351 aa)
KLF4Testis cDNA clone: QtsA-19426, similar to human Kruppel-like factor 4 (gut) (KLF4). (479 aa)
DUSP10Dual specificity phosphatase 10. (488 aa)
FBXW9F-box and WD repeat domain containing 9. (458 aa)
MCCMCC regulator of WNT signaling pathway. (1014 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (657 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
KRIT1Uncharacterized protein. (736 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)- containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
THBS1Thrombospondin 1. (1173 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
CD40CD40 molecule. (278 aa)
HAS2Hyaluronan synthase 2. (552 aa)
APOHUncharacterized protein. (355 aa)
CXCL13C-X-C motif chemokine. (109 aa)
HRGHistidine rich glycoprotein. (525 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (601 aa)
PTPRRProtein tyrosine phosphatase receptor type R. (657 aa)
HIF1AUncharacterized protein. (831 aa)
AMOTAngiomotin. (1099 aa)
VASH1Vasohibin 1. (365 aa)
ADGRB1Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1566 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
SRCTyrosine-protein kinase. (542 aa)
GDF2Growth differentiation factor 2. (429 aa)
SPRED1Sprouty related EVH1 domain containing 1. (444 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
ATOH8Atonal bHLH transcription factor 8. (321 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
DNAJA4DnaJ heat shock protein family (Hsp40) member A4. (426 aa)
SP100SP100 nuclear antigen. (863 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (510 aa)
MAP2K5Uncharacterized protein; Belongs to the protein kinase superfamily. (448 aa)
RHOBRas homolog gene family, member B. (196 aa)
FUT1L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (366 aa)
ZNF580Zinc finger protein 580. (172 aa)
RRASRAS related. (218 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1404 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PLPP3acidPPc domain-containing protein. (353 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
ARSJArylsulfatase family member J. (599 aa)
NR2F2Nuclear receptor subfamily 2 group F member 2. (414 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1069 aa)
TACSTD2Tumor associated calcium signal transducer 2. (323 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
AGTSERPIN domain-containing protein; Belongs to the serpin family. (485 aa)
ENSMFAP00000010473Uncharacterized protein. (212 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
EVLWH1 domain-containing protein. (456 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
MEOX2Mesenchyme homeobox 2. (303 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1935 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1072 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1465 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (182 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
CIB1Calcium and integrin binding 1. (231 aa)
TBXA2RThromboxane A2 receptor. (455 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
CAPN7Calpain 7; Belongs to the peptidase C2 family. (748 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1870 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (584 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
CLASP2Uncharacterized protein. (1514 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (148 aa)
JCADJunctional cadherin 5 associated. (1356 aa)
SYNJ2BPSynaptojanin 2 binding protein. (145 aa)
ENSMFAP00000002824Uncharacterized protein. (781 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (335 aa)
RHOAUncharacterized protein. (141 aa)
RAB25RAB25, member RAS oncogene family. (213 aa)
MACF1Microtubule actin crosslinking factor 1. (7594 aa)
GLULGlutamine synthetase; Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (By similarity). Its role depends on tissue localization: in the brain, it regulates the levels of toxic ammonia and converts neurotoxic glutamate to harmless glutamine, whereas in the liver, it is one of the enzymes responsible for the removal of ammonia (By similarity). Essential for proliferation of fetal skin fibroblasts. Independently of its glutamine synthetase activity, required for endothelial cell migration during vascular development: acts by regulating [...] (373 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (760 aa)
CCBE1Collagen and calcium binding EGF domains 1. (406 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
SASH1SAM and SH3 domain containing 1. (1246 aa)
CALRCalreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis. (417 aa)
GRNUncharacterized protein. (593 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
PATZ1POZ/BTB and AT hook containing zinc finger 1. (687 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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