Your Input: | |||||
APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) | ||||
ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) | ||||
SFRP2 | Secreted frizzled related protein 2. (295 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (393 aa) | ||||
BNIP3 | BCL2 interacting protein 3. (248 aa) | ||||
NOL3 | CARD domain-containing protein. (258 aa) | ||||
RPS6KA2 | Ribosomal protein S6 kinase. (760 aa) | ||||
HEY2 | Hes related family bHLH transcription factor with YRPW motif 2. (337 aa) | ||||
KIFAP3 | Kinesin associated protein 3. (803 aa) | ||||
GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) | ||||
MYOCD | Myocardin. (964 aa) | ||||
TIGAR | TP53 induced glycolysis regulatory phosphatase. (316 aa) |