STRINGSTRING
MTCL1 MTCL1 AKAP7 AKAP7 KCNQ1 KCNQ1 CORO1C CORO1C NSG1 NSG1 ANK3 ANK3 SLC16A1 SLC16A1 DVL1 DVL1 DSG1 DSG1 MARK2 MARK2 CDH1 CDH1 ENSMFAP00000013730 ENSMFAP00000013730 CLDN3 CLDN3 CLDN5 CLDN5 CLDN4 CLDN4 CLDN12 CLDN12 TACSTD2 TACSTD2 VANGL1 VANGL1 LEPR LEPR SLC12A2 SLC12A2 RAB13 RAB13 CTNNB1 CTNNB1 PTPRO PTPRO SLC26A5 SLC26A5 AXIN1 AXIN1 PPP2R1A PPP2R1A DLG1 DLG1 VANGL2 VANGL2 IQGAP3 IQGAP3 MPP7 MPP7 BVES BVES LIN7C LIN7C ATP2B1 ATP2B1 ANXA1 ANXA1 ATP6V1B1 ATP6V1B1 CEACAM1 CEACAM1 PKD1 PKD1 ACTN1 ACTN1 EPCAM EPCAM KCNB1 KCNB1 JUP JUP TBCD TBCD C1QTNF5 C1QTNF5 SLC16A3 SLC16A3 GNA12 GNA12 NKD2 NKD2 ARL2 ARL2 CLDN7 CLDN7 APC APC GPSM2 GPSM2 CLDN1 CLDN1 SCN5A SCN5A BSG BSG LIN7A LIN7A ERBB3 ERBB3 ABCC1 ABCC1 MYO1A MYO1A CLDN15 CLDN15 ATP1B2 ATP1B2 DVL2 DVL2 SLC6A9 SLC6A9 FZD3 FZD3 MYO1C MYO1C IQGAP1 IQGAP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MTCL1Microtubule crosslinking factor 1. (1900 aa)
AKAP7A-kinase anchoring protein 7. (348 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (644 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (527 aa)
NSG1Neuronal vesicle trafficking-associated protein 1; Plays a role in the recycling mechanism in neurons of multiple receptors, including AMPAR, APP and L1CAM and acts at the level of early endosomes to promote sorting of receptors toward a recycling pathway. Regulates sorting and recycling of GRIA2 through interaction with GRIP1 and then contributes to the regulation of synaptic transmission and plasticity by affecting the recycling and targeting of AMPA receptors to the synapse (By similarity). Is required for faithful sorting of L1CAM to axons by facilitating trafficking from somatoden [...] (185 aa)
ANK3Ankyrin 3. (4376 aa)
SLC16A1MFS domain-containing protein. (500 aa)
DVL1Dishevelled segment polarity protein 1. (673 aa)
DSG1Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1051 aa)
MARK2Non-specific serine/threonine protein kinase. (774 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (882 aa)
ENSMFAP00000013730EFhand_Ca_insen domain-containing protein. (97 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
CLDN12Claudin 12. (244 aa)
TACSTD2Tumor associated calcium signal transducer 2. (323 aa)
VANGL1Vang-like protein. (524 aa)
LEPRLeptin receptor. (1163 aa)
SLC12A2Solute carrier family 12 member 2. (1210 aa)
RAB13Uncharacterized protein. (203 aa)
CTNNB1Catenin beta 1. (781 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
SLC26A5Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (748 aa)
AXIN1Axin 1. (867 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A regulatory subunit A. (589 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (938 aa)
VANGL2Vang-like protein. (539 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1632 aa)
MPP7Membrane palmitoylated protein 7; Belongs to the MAGUK family. (576 aa)
BVESBlood vessel epicardial substance. (360 aa)
LIN7CProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
ANXA1Annexin. (346 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
CEACAM1Uncharacterized protein. (525 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4318 aa)
ACTN1Alpha-actinin-1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (By similarity). (914 aa)
EPCAMEpithelial cell adhesion molecule. (288 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
JUPJunction plakoglobin. (745 aa)
TBCDTubulin folding cofactor D. (1138 aa)
C1QTNF5C1q and TNF related 5. (243 aa)
SLC16A3Solute carrier family 16 member 3. (465 aa)
GNA12G protein subunit alpha 12. (381 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (466 aa)
ARL2ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
APCAPC regulator of WNT signaling pathway. (2861 aa)
GPSM2Uncharacterized protein. (686 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
BSGBasigin (Ok blood group). (366 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1353 aa)
ABCC1Multidrug resistance-associated protein 1; Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o- glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export. Hydrolyzes ATP with low efficiency. Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation (By similarity). Participates in [...] (1496 aa)
MYO1AMyosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
CLDN15Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (228 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
SLC6A9Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (706 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1063 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1696 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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