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| | ENSMFAP00000025726 | Uncharacterized protein. (170 aa) |
| | LGMN | Legumain; Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system (By similarity). (433 aa) |
| | PCSK7 | Proprotein convertase subtilisin/kexin type 7. (786 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (421 aa) |
| | TMPRSS2 | Transmembrane serine protease 2; Belongs to the peptidase S1 family. (529 aa) |
| | SPON1 | Spondin 1. (934 aa) |
| | F9 | Coagulation factor IX. (461 aa) |
| | CASP7 | Caspase 7; Belongs to the peptidase C14A family. (377 aa) |
| | FGB | Fibrinogen beta chain. (491 aa) |
| | FGA | Fibrinogen alpha chain. (928 aa) |
| | ECE2 | EEF1AKMT4-ECE2 readthrough. (883 aa) |
| | CTSL | Cathepsin L; Belongs to the peptidase C1 family. (333 aa) |
| | F11 | Coagulation factor XI; Belongs to the peptidase S1 family. (625 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | IFI16 | Interferon gamma inducible protein 16. (729 aa) |
| | ACE | Angiotensin-converting enzyme. (1307 aa) |
| | FXN | Frataxin intermediate form; Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity). (210 aa) |
| | F3 | Coagulation factor III, tissue factor. (296 aa) |
| | PLAT | Plasminogen activator; Belongs to the peptidase S1 family. (562 aa) |
| | DPP4 | Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa) |
| | CPD | Carboxypeptidase D. (1378 aa) |
| | LOC102139474 | Kallikrein related peptidase 2; Belongs to the peptidase S1 family. (223 aa) |
| | CASP2 | Caspase 2; Belongs to the peptidase C14A family. (452 aa) |
| | KEL | Kell metallo-endopeptidase (Kell blood group). (732 aa) |
| | PRR14L | Proline rich 14 like. (2150 aa) |
| | TMEM208 | Transmembrane protein 208. (173 aa) |
| | FAM111A | Family with sequence similarity 111 member A. (611 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa) |
| | TBC1D10A | TBC1 domain family member 10A. (508 aa) |
| | SLC30A5 | Solute carrier family 30 member 5. (764 aa) |
| | SEC11C | Signal peptidase complex catalytic subunit SEC11. (192 aa) |
| | SPPL3 | Signal peptide peptidase like 3. (384 aa) |
| | CD5L | CD5 molecule like. (347 aa) |
| | TLL2 | Metalloendopeptidase. (1015 aa) |
| | DHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa) |
| | ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif 2. (1198 aa) |
| | SLC30A6 | Solute carrier family 30 member 6. (461 aa) |
| | SLC30A8 | Solute carrier family 30 member 8. (369 aa) |
| | CPXM1 | Carboxypeptidase X, M14 family member 1. (732 aa) |
| | CPLANE2 | Ciliogenesis and planar polarity effector 2. (258 aa) |
| | NCSTN | Ncstrn_small domain-containing protein. (721 aa) |
| | ENSMFAP00000034700 | Peptidase_M13_N domain-containing protein. (272 aa) |
| | ADAM10 | ADAM metallopeptidase domain 10. (748 aa) |
| | CPA3 | Carboxypeptidase A3. (432 aa) |
| | COMP | Cartilage oligomeric matrix protein. (757 aa) |
| | KLK6 | Kallikrein related peptidase 6; Belongs to the peptidase S1 family. (244 aa) |
| | SPCS2 | Signal peptidase complex subunit 2; Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. (257 aa) |
| | ENSMFAP00000035602 | Uncharacterized protein. (178 aa) |
| | PERP | PERP, TP53 apoptosis effector. (193 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (891 aa) |
| | ECEL1 | Endothelin converting enzyme like 1. (775 aa) |
| | CASP8 | Uncharacterized protein; Belongs to the peptidase C14A family. (538 aa) |
| | PCSK2 | Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family. (638 aa) |
| | NLRC4 | NLR family CARD domain containing 4. (1024 aa) |
| | CNTN2 | Contactin 2. (1040 aa) |
| | HM13 | Histocompatibility minor 13. (425 aa) |
| | PLAU | Plasminogen activator, urokinase. (430 aa) |
| | ATP6AP2 | ATPase H+ transporting accessory protein 2. (350 aa) |
| | CTSS | Cathepsin S; Belongs to the peptidase C1 family. (331 aa) |
| | CPZ | Carboxypeptidase Z. (652 aa) |
| | IL1R2 | Interleukin 1 receptor type 2. (398 aa) |
| | TMPRSS4 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (437 aa) |
| | MMEL1 | Membrane metalloendopeptidase like 1. (779 aa) |
| | IFT172 | Intraflagellar transport 172. (1749 aa) |
| | MBOAT4 | Membrane bound O-acyltransferase domain containing 4; Belongs to the membrane-bound acyltransferase family. (435 aa) |
| | F8 | Coagulation factor VIII; Belongs to the multicopper oxidase family. (2351 aa) |
| | YME1L1 | AAA domain-containing protein. (763 aa) |
| | METAP2 | Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. (478 aa) |
| | DDI2 | DNA damage inducible 1 homolog 2. (399 aa) |
| | MMP16 | Matrix metallopeptidase 16. (607 aa) |
| | ADAM19 | ADAM metallopeptidase domain 19. (918 aa) |
| | STOML2 | Stomatin like 2. (361 aa) |
| | CARD16 | CARD domain-containing protein. (97 aa) |
| | ADAM17 | ADAM metallopeptidase domain 17. (824 aa) |
| | IMMP2L | Mitochondrial inner membrane protease subunit. (175 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | PCSK1N | Proprotein convertase subtilisin/kexin type 1 inhibitor. (265 aa) |
| | MYRF | Myelin regulatory factor. (1151 aa) |
| | ADAM9 | ADAM metallopeptidase domain 9. (819 aa) |
| | PCSK5 | Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1887 aa) |
| | MME | Membrane metalloendopeptidase. (750 aa) |
| | APH1B | Uncharacterized protein. (257 aa) |
| | KLK13 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (277 aa) |
| | PCSK4 | Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (758 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa) |
| | ENSMFAP00000005012 | Signal peptidase complex catalytic subunit SEC11. (157 aa) |
| | FGG | Fibrinogen gamma chain. (453 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) |
| | RCE1 | Ras converting CAAX endopeptidase 1. (329 aa) |
| | PMPCA | Peptidase, mitochondrial processing alpha subunit; Belongs to the peptidase M16 family. (525 aa) |
| | PAWR | Pro-apoptotic WT1 regulator. (342 aa) |
| | ENSMFAP00000003683 | Uncharacterized protein. (155 aa) |
| | YIPF5 | Protein YIPF5; Plays a role in transport between endoplasmic reticulum and Golgi. (257 aa) |
| | PMPCB | Uncharacterized protein; Belongs to the peptidase M16 family. (493 aa) |
| | PLA2G7 | Platelet-activating factor acetylhydrolase. (439 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa) |
| | SEC11A | Signal peptidase complex catalytic subunit SEC11. (185 aa) |
| | ENSMFAP00000002824 | Uncharacterized protein. (781 aa) |
| | CTSH | Cathepsin H; Belongs to the peptidase C1 family. (335 aa) |
| | MMP14 | Matrix metallopeptidase 14. (582 aa) |
| | PSEN2 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa) |
| | PCSK9 | Proprotein convertase subtilisin/kexin type 9. (811 aa) |
| | HGFAC | HGF activator. (657 aa) |
| | MYRFL | Myelin regulatory factor like. (910 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa) |
| | CPXM2 | Carboxypeptidase X, M14 family member 2. (756 aa) |
| | SPRTN | SprT-like N-terminal domain. (488 aa) |
| | SRGN | Serglycin. (153 aa) |
| | ENSMFAP00000006785 | Uncharacterized protein. (285 aa) |
| | PSEN1 | Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels. Stimulates cell-cell adhesion via its interaction with CDH1; this stabili [...] (467 aa) |
| | DISP1 | Dispatched RND transporter family member 1. (1523 aa) |
| | CTSG | Cathepsin G; Belongs to the peptidase S1 family. (255 aa) |
| | TYSND1 | Trypsin domain containing 1. (566 aa) |
| | MEP1A | Meprin A subunit. (746 aa) |
| | CASP6 | Uncharacterized protein; Belongs to the peptidase C14A family. (293 aa) |
| | ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif 13. (1431 aa) |
| | BMP1 | Metalloendopeptidase. (986 aa) |
| | PHEX | Phosphate regulating endopeptidase homolog X-linked. (749 aa) |
| | DYNC2H1 | Dynein cytoplasmic 2 heavy chain 1. (4314 aa) |
| | NLRP6 | NLR family pyrin domain containing 6. (1044 aa) |
| | SPCS1 | Signal peptidase complex subunit 1. (169 aa) |
| | ENSMFAP00000000657 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (268 aa) |
| | HJV | Hemojuvelin BMP co-receptor. (427 aa) |
| | XPNPEP3 | AMP_N domain-containing protein. (507 aa) |
| | F5 | Coagulation factor V; Belongs to the multicopper oxidase family. (2181 aa) |
| | PSENEN | Presenilin enhancer, gamma-secretase subunit. (101 aa) |
| | C1RL | Complement C1r subcomponent like; Belongs to the peptidase S1 family. (481 aa) |
| | APH1A | Uncharacterized protein. (265 aa) |
| | CUZD1 | Uncharacterized protein. (607 aa) |
| | FURIN | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa) |
| | CTSZ | Cathepsin Z; Belongs to the peptidase C1 family. (368 aa) |
| | SPCS3 | Signal peptidase complex subunit 3. (180 aa) |
| | SPG7 | SPG7 matrix AAA peptidase subunit, paraplegin. (794 aa) |
| | PISD | Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. (409 aa) |
| | CASP1 | Caspase 1; Belongs to the peptidase C14A family. (404 aa) |
| | TLL1 | Metalloendopeptidase. (1036 aa) |
| | REN | Renin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. (406 aa) |
| | ERO1A | Endoplasmic reticulum oxidoreductase 1 alpha. (468 aa) |
| | CORIN | Corin, serine peptidase. (1111 aa) |
| | CPN1 | Carboxypeptidase N subunit 1. (459 aa) |
| | TMPRSS12 | Transmembrane serine protease 12; Belongs to the peptidase S1 family. (348 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) |
| | GLG1 | Golgi glycoprotein 1. (1203 aa) |
| | ENSMFAP00000012235 | Uncharacterized protein; Belongs to the peptidase C1 family. (333 aa) |
| | FKRP | Fukutin related protein. (495 aa) |
| | CTSE | Cathepsin E; Belongs to the peptidase A1 family. (396 aa) |
| | C2CD3 | C2 domain containing 3 centriole elongation regulator. (2353 aa) |
| | ASPRV1 | Aspartic peptidase retroviral like 1. (343 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | IMMP1L-2 | Inner mitochondrial membrane peptidase subunit 1. (57 aa) |
| | LONP2 | Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (825 aa) |
| | IMMP1L | Mitochondrial inner membrane protease subunit. (166 aa) |
| | PRSS12 | Serine protease 12; Belongs to the peptidase S1 family. (875 aa) |
| | GLI3 | GLI family zinc finger 3. (1579 aa) |
| | PIDD1 | P53-induced death domain protein 1. (910 aa) |
| | SDE2 | SDE2 telomere maintenance homolog. (451 aa) |
| | VSIR | V-set immunoregulatory receptor. (311 aa) |
| | ENSMFAP00000016524 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (436 aa) |
| | ASPH | Aspartate beta-hydroxylase. (762 aa) |
| | BACE1 | Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa) |
| | ATP23 | Mitochondrial inner membrane protease ATP23; Belongs to the peptidase M76 family. (246 aa) |
| | PTCH1 | Patched 1. (1398 aa) |
| | MBTPS1 | Membrane bound transcription factor peptidase, site 1. (1054 aa) |
| | BACE2 | Beta-secretase 2; Belongs to the peptidase A1 family. (518 aa) |
| | SCG5 | Uncharacterized protein. (211 aa) |
| | F12 | Coagulation factor XII. (615 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) |
| | APOH | Uncharacterized protein. (355 aa) |
| | PCSK6 | Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (944 aa) |
| | CIDEB | Cell death inducing DFFA like effector b. (220 aa) |
| | PCSK1 | Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (749 aa) |
| | OMA1 | Peptidase_M48 domain-containing protein. (524 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | HTRA2 | HtrA serine peptidase 2. (458 aa) |
| | CASP4 | Caspase 4; Belongs to the peptidase C14A family. (377 aa) |
| | ENSMFAP00000022286 | Uncharacterized protein. (156 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | LOC102138490 | AAA domain-containing protein. (736 aa) |
| | AFG3L2 | AFG3 like matrix AAA peptidase subunit 2. (800 aa) |
| | ENSMFAP00000023287 | Uncharacterized protein. (145 aa) |
| | ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif 3. (1205 aa) |
| | ECE1 | Endothelin converting enzyme 1. (769 aa) |
| | ENPEP | Aminopeptidase. (957 aa) |
| | F10 | Coagulation factor X. (488 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (490 aa) |
| | ENSMFAP00000025660 | Uncharacterized protein. (342 aa) |
