STRINGSTRING
SPIRE1 SPIRE1 NDE1 NDE1 PSD PSD MYH10 MYH10 SPIRE2 SPIRE2 SEPTIN2 SEPTIN2 ECT2 ECT2 CEP55 CEP55 PSTPIP1 PSTPIP1 PITPNM1 PITPNM1 KATNBL1 KATNBL1 PPP1CC PPP1CC RAB11FIP3 RAB11FIP3 ICAM2 ICAM2 PKN1 PKN1 WDR73 WDR73 NF2 NF2 LOC107126507 LOC107126507 RHOC RHOC ANKRD45 ANKRD45 PLK4 PLK4 DCTN3 DCTN3 SEPTIN6 SEPTIN6 SSH1 SSH1 LOC102146064 LOC102146064 SEPTIN7 SEPTIN7 FSD1 FSD1 PLCD3 PLCD3 ENSMFAP00000026182 ENSMFAP00000026182 HTR3A HTR3A RAB21 RAB21 SEPTIN12 SEPTIN12 ZFYVE19 ZFYVE19 PSD2 PSD2 PLEKHG6 PLEKHG6 RDX RDX MASTL MASTL PKN2 PKN2 RHOB RHOB RACGAP1 RACGAP1 MYH9 MYH9 LOC102125303 LOC102125303 HMCN2 HMCN2 RAB11FIP4 RAB11FIP4 MEN1 MEN1 CIT CIT LIMA1 LIMA1 STAMBP STAMBP RALA RALA ARF6 ARF6 RHOA RHOA MYLK MYLK ENSMFAP00000001163 ENSMFAP00000001163 HMCN1 HMCN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPIRE1Protein spire homolog 1; Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during oocyte meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis. Also acts in the nucleus: together with FMN2, promotes assembly of nuclear actin filaments in [...] (757 aa)
NDE1NUDE_C domain-containing protein. (377 aa)
PSDPleckstrin and Sec7 domain containing. (1024 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
SPIRE2Spire type actin nucleation factor 2. (714 aa)
SEPTIN2Septin 2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (396 aa)
ECT2Epithelial cell transforming 2. (914 aa)
CEP55Centrosomal protein 55. (464 aa)
PSTPIP1Proline-serine-threonine phosphatase interacting protein 1. (413 aa)
PITPNM1Phosphatidylinositol transfer protein membrane associated 1. (1244 aa)
KATNBL1Katanin regulatory subunit B1 like 1. (304 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa)
RAB11FIP3RAB11 family interacting protein 3. (680 aa)
ICAM2Intercellular adhesion molecule 2. (275 aa)
PKN1Protein kinase N1. (949 aa)
WDR73WD repeat domain 73. (372 aa)
NF2Neurofibromin 2. (595 aa)
LOC107126507HP domain-containing protein. (81 aa)
RHOCRas homolog family member C. (193 aa)
ANKRD45ANK_REP_REGION domain-containing protein. (266 aa)
PLK4Polo like kinase 4. (970 aa)
DCTN3Dynactin subunit 3. (186 aa)
SEPTIN6Septin 6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (439 aa)
SSH1Slingshot protein phosphatase 1. (1071 aa)
LOC102146064Uncharacterized protein. (3024 aa)
SEPTIN7Septin 7; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (436 aa)
FSD1Fibronectin type III and SPRY domain-containing protein 1; May be involved in microtubule organization and stabilization. (498 aa)
PLCD3Phosphoinositide phospholipase C. (785 aa)
ENSMFAP00000026182Uncharacterized protein. (183 aa)
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (515 aa)
RAB21RAB21, member RAS oncogene family. (232 aa)
SEPTIN12Septin 12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (358 aa)
ZFYVE19Zinc finger FYVE-type containing 19. (470 aa)
PSD2Pleckstrin and Sec7 domain containing 2. (771 aa)
PLEKHG6Pleckstrin homology and RhoGEF domain containing G6. (790 aa)
RDXFERM domain-containing protein. (604 aa)
MASTLMicrotubule associated serine/threonine kinase like. (879 aa)
PKN2Protein kinase N2. (983 aa)
RHOBRas homolog gene family, member B. (196 aa)
RACGAP1Rac GTPase activating protein 1. (632 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
LOC102125303Supervillin. (2221 aa)
HMCN2Uncharacterized protein. (584 aa)
RAB11FIP4RAB11 family interacting protein 4. (634 aa)
MEN1Menin 1. (615 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2069 aa)
LIMA1LIM domain and actin binding 1. (761 aa)
STAMBPSTAM binding protein. (424 aa)
RALARAS like proto-oncogene A. (206 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (148 aa)
RHOAUncharacterized protein. (141 aa)
MYLKMyosin light chain kinase. (1914 aa)
ENSMFAP00000001163Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (417 aa)
HMCN1Hemicentin 1. (5635 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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