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PAQR3 PAQR3 PWP1 PWP1 BDKRB2 BDKRB2 BAK1 BAK1 INPP5K INPP5K ENSMFAP00000014471 ENSMFAP00000014471 LOC102140140 LOC102140140 INPP5J INPP5J DDIT4 DDIT4 BAX BAX NCK2 NCK2 ENSMFAP00000022286 ENSMFAP00000022286 SMAD7 SMAD7 GADD45A GADD45A RACK1 RACK1 NCK1 NCK1 DMD DMD PDE4D PDE4D INPP5F INPP5F RASSF2 RASSF2 EPM2A EPM2A GGNBP2 GGNBP2 DMTN DMTN PTEN PTEN HGF HGF MLXIPL MLXIPL DKK1 DKK1 CAV1 CAV1 PPM1F PPM1F
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PAQR3Uncharacterized protein. (311 aa)
PWP1WD_REPEATS_REGION domain-containing protein. (503 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (391 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (450 aa)
ENSMFAP00000014471WD_REPEATS_REGION domain-containing protein. (438 aa)
LOC102140140BHLH domain-containing protein. (412 aa)
INPP5JInositol polyphosphate-5-phosphatase J. (1001 aa)
DDIT4DNA damage inducible transcript 4. (233 aa)
BAXBCL2 associated X, apoptosis regulator. (203 aa)
NCK2Cytoplasmic protein. (382 aa)
ENSMFAP00000022286Uncharacterized protein. (156 aa)
SMAD7Mothers against decapentaplegic homolog. (495 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (165 aa)
RACK1Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed; Involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Component of the 40S ribosomal subunit involved in translational repression. Binds to and stabilizes activated protein kinase C (PKC), increasing PKC- mediated phosphorylation. May recruit activated PKC to the ribosome, leading to phosphorylation of EIF6. Inhibits the activity of SRC kinases including SRC, LCK and YES1. Inhibits [...] (393 aa)
NCK1Cytoplasmic protein. (377 aa)
DMDDystrophin. (3685 aa)
PDE4DPhosphodiesterase. (809 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (1133 aa)
RASSF2Uncharacterized protein. (326 aa)
EPM2AEPM2A glucan phosphatase, laforin. (331 aa)
GGNBP2Gametogenetin binding protein 2. (699 aa)
DMTNDematin actin binding protein. (412 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
HGFHepatocyte growth factor; Belongs to the peptidase S1 family. (788 aa)
MLXIPLUncharacterized protein. (244 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (455 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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