(20 nodes) Response to laminar fluid shear stress network (Macaca fascicularis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	SMAD6	Mothers against decapentaplegic homolog. (496 aa)
	NFE2L2	Nuclear factor, erythroid 2 like 2. (606 aa)
	ASS1	Uncharacterized protein. (412 aa)
	ENSMFAP00000031547	Uncharacterized protein. (178 aa)
	MAPK7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (816 aa)
	ENSMFAP00000027857	Uncharacterized protein. (375 aa)
	ENSMFAP00000025201	Uncharacterized protein. (423 aa)
	SREBF2	Sterol regulatory element binding transcription factor 2. (1142 aa)
	SMAD7	Mothers against decapentaplegic homolog. (495 aa)
	KLF4	Testis cDNA clone: QtsA-19426, similar to human Kruppel-like factor 4 (gut) (KLF4). (479 aa)
	ENSMFAP00000016088	Uncharacterized protein. (123 aa)
	MAP2K5	Uncharacterized protein; Belongs to the protein kinase superfamily. (448 aa)
	LOC102139817	Uncharacterized protein. (446 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	ENSMFAP00000011662	Uncharacterized protein. (111 aa)
	ENSMFAP00000010678	Uncharacterized protein. (111 aa)
	ENSMFAP00000006010	Uncharacterized protein. (370 aa)
	ABCA1	ATP binding cassette subfamily A member 1. (2268 aa)
	XBP1	BZIP domain-containing protein. (380 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)

Your Current Organism:

Macaca fascicularis

NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	SREBF2	ENSMFAP00000005316	ENSMFAP00000023547	ATP binding cassette subfamily A member 1.	Sterol regulatory element binding transcription factor 2.	0.665
ASS1	LOC102139817	ENSMFAP00000033657	ENSMFAP00000013452	Uncharacterized protein.	Uncharacterized protein.	0.900
ENSMFAP00000010678	ENSMFAP00000031547	ENSMFAP00000010678	ENSMFAP00000031547	Uncharacterized protein.	Uncharacterized protein.	0.729
ENSMFAP00000011662	ENSMFAP00000031547	ENSMFAP00000011662	ENSMFAP00000031547	Uncharacterized protein.	Uncharacterized protein.	0.826
ENSMFAP00000016088	MAPK7	ENSMFAP00000016088	ENSMFAP00000029069	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.409
ENSMFAP00000031547	ENSMFAP00000010678	ENSMFAP00000031547	ENSMFAP00000010678	Uncharacterized protein.	Uncharacterized protein.	0.729
ENSMFAP00000031547	ENSMFAP00000011662	ENSMFAP00000031547	ENSMFAP00000011662	Uncharacterized protein.	Uncharacterized protein.	0.826
LOC102139817	ASS1	ENSMFAP00000013452	ENSMFAP00000033657	Uncharacterized protein.	Uncharacterized protein.	0.900
MAP2K5	MAPK7	ENSMFAP00000014537	ENSMFAP00000029069	Uncharacterized protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.995
MAPK7	ENSMFAP00000016088	ENSMFAP00000029069	ENSMFAP00000016088	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.409
MAPK7	MAP2K5	ENSMFAP00000029069	ENSMFAP00000014537	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.995
MAPK7	NFE2L2	ENSMFAP00000029069	ENSMFAP00000040664	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Nuclear factor, erythroid 2 like 2.	0.921
NFE2L2	MAPK7	ENSMFAP00000040664	ENSMFAP00000029069	Nuclear factor, erythroid 2 like 2.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.921
NFE2L2	XBP1	ENSMFAP00000040664	ENSMFAP00000001692	Nuclear factor, erythroid 2 like 2.	BZIP domain-containing protein.	0.547
SMAD6	SMAD7	ENSMFAP00000027553	ENSMFAP00000022604	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.948
SMAD6	TGFB1	ENSMFAP00000027553	ENSMFAP00000000106	Mothers against decapentaplegic homolog.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.738
SMAD7	SMAD6	ENSMFAP00000022604	ENSMFAP00000027553	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.948
SMAD7	TGFB1	ENSMFAP00000022604	ENSMFAP00000000106	Mothers against decapentaplegic homolog.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.867
SMAD7	TGFB3	ENSMFAP00000022604	ENSMFAP00000012543	Mothers against decapentaplegic homolog.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.556
SREBF2	ABCA1	ENSMFAP00000023547	ENSMFAP00000005316	Sterol regulatory element binding transcription factor 2.	ATP binding cassette subfamily A member 1.	0.665

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