STRINGSTRING
AP2A1 AP2A1 CLTC CLTC SLC15A4 SLC15A4 RNF167 RNF167 ATG16L1 ATG16L1 CLEC16A CLEC16A TLR8 TLR8 TPCN2 TPCN2 CXorf21 CXorf21 AP2A2 AP2A2 AP2B1 AP2B1 ABCB6 ABCB6 CLTA CLTA TLR7 TLR7 LDLR LDLR TLR3 TLR3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (977 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
SLC15A4Solute carrier family 15 member 4. (496 aa)
RNF167Ring finger protein 167. (350 aa)
ATG16L1Autophagy related 16 like 1. (624 aa)
CLEC16AC-type lectin domain containing 16A. (1053 aa)
TLR8TIR domain-containing protein; Belongs to the Toll-like receptor family. (1058 aa)
TPCN2Two pore segment channel 2. (752 aa)
CXorf21Chromosome X open reading frame 21. (301 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (940 aa)
AP2B1AP complex subunit beta. (951 aa)
ABCB6ATP binding cassette subfamily B member 6 (Langereis blood group). (843 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
TLR7Toll-like receptor 7; Belongs to the Toll-like receptor family. (1049 aa)
LDLRLow density lipoprotein receptor. (860 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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