STRINGSTRING
BSG BSG BCL2L11 BCL2L11 STIM1 STIM1 MSX1 MSX1 ENSMFAP00000043974 ENSMFAP00000043974 SERPINE1 SERPINE1 HAND1 HAND1 CCDC154 CCDC154 TRAF6 TRAF6 SCN5A SCN5A DLX1 DLX1 LAMA5 LAMA5 CTNNA1 CTNNA1 ACVR2B ACVR2B WDR72 WDR72 NECTIN1 NECTIN1 HAND2 HAND2 AMBN AMBN JAG2 JAG2 SLC24A4 SLC24A4 PERP PERP RUNX2 RUNX2 LRP4 LRP4 NF2 NF2 FGF10 FGF10 ROGDI ROGDI GLI2 GLI2 ACVR2A ACVR2A LEF1 LEF1 SHH SHH AMTN AMTN KLK5 KLK5 EDA EDA EDAR EDAR FGF4 FGF4 TBX1 TBX1 SMO SMO DLX2 DLX2 ODAM ODAM GATA6 GATA6 HTRA1 HTRA1 NKX2-3 NKX2-3 ENSMFAP00000025726 ENSMFAP00000025726 ENSMFAP00000025317 ENSMFAP00000025317 BMP2 BMP2 NGFR NGFR WNT6 WNT6 FAM20C FAM20C TP63 TP63 BAX BAX FAM20A FAM20A FOXC1 FOXC1 RELT RELT CNNM4 CNNM4 BCL11B BCL11B DLX3 DLX3 BMP7 BMP7 DSPP DSPP PPARA PPARA SLC34A1 SLC34A1 GLI3 GLI3 ENAM ENAM FST FST TCIRG1 TCIRG1 ENSMFAP00000013287 ENSMFAP00000013287 SOSTDC1 SOSTDC1 ENSMFAP00000010148 ENSMFAP00000010148 HDAC1 HDAC1 BMP4 BMP4 CTNNB1 CTNNB1 LHX8 LHX8 CFTR CFTR BMPR1A BMPR1A ENSMFAP00000005981 ENSMFAP00000005981 ATF2 ATF2 KLK4 KLK4 SMPD3 SMPD3 ITGB6 ITGB6 SCN10A SCN10A ADM ADM MMP20 MMP20 AMELX AMELX ANKRD11 ANKRD11 TGFB1 TGFB1 HDAC2 HDAC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BSGBasigin (Ok blood group). (366 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
STIM1Stromal interaction molecule 1. (770 aa)
MSX1Msh homeobox 1. (303 aa)
ENSMFAP00000043974Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (462 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
CCDC154Coiled-coil domain containing 154. (522 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
DLX1Homeobox domain-containing protein. (255 aa)
LAMA5Laminin subunit alpha 5. (3699 aa)
CTNNA1Catenin alpha 1. (906 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (518 aa)
WDR72WD repeat domain 72. (1100 aa)
NECTIN1Nectin cell adhesion molecule 1. (519 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
AMBNAmeloblastin. (447 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1075 aa)
SLC24A4Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (622 aa)
PERPPERP, TP53 apoptosis effector. (193 aa)
RUNX2RUNX family transcription factor 2. (627 aa)
LRP4LDL receptor related protein 4. (1913 aa)
NF2Neurofibromin 2. (595 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ROGDIRogdi atypical leucine zipper. (287 aa)
GLI2GLI family zinc finger 2. (1561 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
AMTNAmelotin. (208 aa)
KLK5Kallikrein related peptidase 5; Belongs to the peptidase S1 family. (291 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (391 aa)
EDAREctodysplasin A receptor. (496 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
TBX1T-box transcription factor 1. (441 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
DLX2Distal-less homeobox 2. (328 aa)
ODAMOdontogenic, ameloblast associated. (279 aa)
GATA6GATA binding protein 6. (557 aa)
HTRA1HtrA serine peptidase 1. (481 aa)
NKX2-3NK2 homeobox 3. (364 aa)
ENSMFAP00000025726Uncharacterized protein. (170 aa)
ENSMFAP00000025317Hist_deacetyl domain-containing protein. (258 aa)
BMP2Bone morphogenetic protein 2. (544 aa)
NGFRNerve growth factor receptor. (427 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (584 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (686 aa)
BAXBCL2 associated X, apoptosis regulator. (203 aa)
FAM20AFAM20A golgi associated secretory pathway pseudokinase. (533 aa)
FOXC1Forkhead box C1. (504 aa)
RELTTumor necrosis factor receptor superfamily member 19L; May play a role in apoptosis. Induces activation of MAPK14/p38 and MAPK8/JNK MAPK cascades, when overexpressed. Involved in dental enamel formation; Belongs to the RELT family. (440 aa)
CNNM4Cyclin and CBS domain divalent metal cation transport mediator 4. (775 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (870 aa)
DLX3Distal-less homeobox 3. (287 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
DSPPDentin sialophosphoprotein. (1216 aa)
PPARAPeroxisome proliferator activated receptor alpha. (467 aa)
SLC34A1Solute carrier family 34 member 1. (680 aa)
GLI3GLI family zinc finger 3. (1579 aa)
ENAMEnamelin. (1138 aa)
FSTFollistatin. (344 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
ENSMFAP00000013287TNF receptor-associated factor. (474 aa)
SOSTDC1Sclerostin domain containing 1. (230 aa)
ENSMFAP00000010148Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (421 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
CTNNB1Catenin beta 1. (781 aa)
LHX8LIM homeobox 8. (377 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1484 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ENSMFAP00000005981Uncharacterized protein. (471 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
KLK4Kallikrein related peptidase 4; Belongs to the peptidase S1 family. (254 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1959 aa)
ADMAdrenomedullin. (185 aa)
MMP20Matrix metallopeptidase 20. (483 aa)
AMELXUncharacterized protein. (205 aa)
ANKRD11Ankyrin repeat domain 11. (2657 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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