STRINGSTRING
HLTF HLTF SUPT6H SUPT6H STAT3 STAT3 TAF13 TAF13 TAF1 TAF1 NR1H3 NR1H3 TFCP2 TFCP2 TAF4 TAF4 ATF2 ATF2 TAF10 TAF10 ENSMFAP00000006813 ENSMFAP00000006813 TAF8 TAF8 THRB THRB NCOA2 NCOA2 ZIC3 ZIC3 SREBF1 SREBF1 NCBP1 NCBP1 TBP TBP TAF5 TAF5 HNRNPD HNRNPD TAF4B TAF4B THRA THRA RARA RARA ENSMFAP00000022059 ENSMFAP00000022059 TAF6 TAF6 ENSMFAP00000022646 ENSMFAP00000022646 RXRA RXRA S100A10 S100A10 LOC101866545 LOC101866545 ZBTB1 ZBTB1 TAF2 TAF2 EPAS1 EPAS1 VDR VDR MED1 MED1 NCOA1 NCOA1 TAF3 TAF3 TAF12 TAF12 AP3B1 AP3B1 CREB1 CREB1 ATF4 ATF4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HLTFHelicase like transcription factor. (1013 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1732 aa)
STAT3Signal transducer and activator of transcription. (802 aa)
TAF13Transcription initiation factor TFIID subunit 13. (124 aa)
TAF1Transcription initiation factor TFIID subunit. (1927 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (453 aa)
TFCP2Transcription factor CP2. (502 aa)
TAF4TATA-box binding protein associated factor 4. (635 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
ENSMFAP00000006813Uncharacterized protein. (245 aa)
TAF8TATA-box binding protein associated factor 8. (338 aa)
THRBUncharacterized protein. (476 aa)
NCOA2Nuclear receptor coactivator. (1464 aa)
ZIC3Zic family member 3. (488 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1177 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
TBPTATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of a BRF2-containing transcription factor complex that regulates transcription mediated by RNA polymerase III. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase [...] (326 aa)
TAF5TATA-box binding protein associated factor 5. (800 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D. (355 aa)
TAF4BTATA-box binding protein associated factor 4b. (813 aa)
THRAUncharacterized protein. (602 aa)
RARARetinoic acid receptor alpha. (462 aa)
ENSMFAP00000022059Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (189 aa)
TAF6TATA-box binding protein associated factor 6. (736 aa)
ENSMFAP00000022646Uncharacterized protein. (264 aa)
RXRARetinoid X receptor alpha. (443 aa)
S100A10S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
LOC101866545Uncharacterized protein. (101 aa)
ZBTB1Zinc finger and BTB domain containing 1. (667 aa)
TAF2TATA-box binding protein associated factor 2. (1199 aa)
EPAS1Endothelial PAS domain protein 1. (869 aa)
VDRVitamin D receptor. (477 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa)
NCOA1Nuclear receptor coactivator 1. (1534 aa)
TAF3TATA-box binding protein associated factor 3. (1008 aa)
TAF12TATA-box binding protein associated factor 12. (213 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1063 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
ATF4Activating transcription factor 4. (351 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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