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| | SLAMF1 | Signaling lymphocytic activation molecule family member 1. (356 aa) |
| | PLD4 | Phospholipase D family member 4. (506 aa) |
| | RAB34 | Uncharacterized protein. (263 aa) |
| | STXBP4 | Syntaxin binding protein 4. (555 aa) |
| | RAB10 | RAB10, member RAS oncogene family. (200 aa) |
| | UVRAG | UV radiation resistance associated. (699 aa) |
| | MCOLN1 | Mucolipin-1; Nonselective cation channel probably playing a role in the regulation of membrane trafficking events and of metal homeostasis. Proposed to play a major role in Ca(2+) release from late endosome and lysosome vesicles to the cytoplasm, which is important for many lysosome-dependent cellular events, including the fusion and trafficking of these organelles, exocytosis and autophagy. Required for efficient uptake of large particles in macrophages in which Ca(2+) release from the lysosomes triggers lysosomal exocytosis. May also play a role in phagosome-lysosome fusion. Involved [...] (580 aa) |
| | AMBRA1 | Autophagy and beclin 1 regulator 1. (1298 aa) |
| | ABCA1 | ATP binding cassette subfamily A member 1. (2268 aa) |
| | RAB5A | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] (215 aa) |
| | LOC102125623 | Ig-like domain-containing protein; Belongs to the MHC class I family. (389 aa) |
| | WAS | WASP actin nucleation promoting factor. (503 aa) |
| | RAB7A | RAB7A, member RAS oncogene family. (207 aa) |
| | ATG14 | Autophagy related 14. (510 aa) |
| | ENSMFAP00000006752 | INPP5B_PH domain-containing protein. (224 aa) |
| | CYBB | Cytochrome b-245 beta chain. (570 aa) |
| | RAB8B | RAB8B, member RAS oncogene family. (207 aa) |
| | NCF2 | Neutrophil cytosolic factor 2. (526 aa) |
| | RILP | Rab interacting lysosomal protein. (395 aa) |
| | TAPBP | TAP binding protein. (504 aa) |
| | APPL1 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (715 aa) |
| | LOC102136620 | Uncharacterized protein. (64 aa) |
| | MPEG1 | Macrophage expressed 1. (696 aa) |
| | ITGB5 | Integrin beta; Belongs to the integrin beta chain family. (799 aa) |
| | ENSMFAP00000010727 | Uncharacterized protein. (98 aa) |
| | HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (830 aa) |
| | RAB9B | RAB9B, member RAS oncogene family. (201 aa) |
| | TLR2 | Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (784 aa) |
| | RAB9A | RAB9A, member RAS oncogene family. (201 aa) |
| | CDC42EP2 | Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family. (210 aa) |
| | RAB11FIP5 | Uncharacterized protein. (1319 aa) |
| | LAMP2 | Lysosomal associated membrane protein 2. (411 aa) |
| | TLR1 | Toll-like receptor. (786 aa) |
| | MPO | Myeloperoxidase. (745 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa) |
| | CORO1A | Coronin-1A; May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. (461 aa) |
| | VAMP7 | Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa) |
| | RAB20 | RAB20, member RAS oncogene family. (234 aa) |
| | LAMP1 | Lysosomal associated membrane protein 1. (423 aa) |
| | ZDHHC5 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (715 aa) |
| | RAB7B | RAB7B, member RAS oncogene family. (189 aa) |
| | STX8 | Syntaxin 8. (236 aa) |
| | CYBA | Cytochrome b-245 alpha chain. (197 aa) |
| | RAB23 | RAB23, member RAS oncogene family. (237 aa) |
| | STX6 | Syntaxin 6; Belongs to the syntaxin family. (255 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | PLA2G5 | Phospholipase A(2). (138 aa) |
| | FMNL1 | Formin like 1. (1107 aa) |
| | GNLY | Granulysin. (153 aa) |
| | OCRL | OCRL inositol polyphosphate-5-phosphatase. (901 aa) |
| | RAB8A | Ras-related protein Rab-8A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in polarized vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes t [...] (207 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (893 aa) |
| | SYT7 | Synaptotagmin 7. (686 aa) |
| | RAB39A | RAB39A, member RAS oncogene family. (217 aa) |
| | UNC93B1 | Unc-93 homolog B1, TLR signaling regulator. (597 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (666 aa) |
| | ATP6V0C | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (128 aa) |
| | CD36 | CD36 molecule; Belongs to the CD36 family. (472 aa) |
| | RAB22A | RAB22A, member RAS oncogene family. (194 aa) |
| | ZYX | Zyxin. (572 aa) |
| | SLC11A1 | Solute carrier family 11 member 1. (547 aa) |
| | CLEC4E | C-type lectin domain family 4 member E. (219 aa) |
| | SCIMP | SLP adaptor and CSK interacting membrane protein. (143 aa) |
| | PIP4P2 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa) |
| | ATP6V0A4 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (838 aa) |
| | MYO1C | Myosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1063 aa) |
| | LOC102132408 | Ig-like domain-containing protein; Belongs to the MHC class I family. (402 aa) |
| | RAB38 | RAB38, member RAS oncogene family. (211 aa) |
| | LOC102123548 | Ig-like domain-containing protein; Belongs to the MHC class I family. (363 aa) |
| | STX4 | Syntaxin 4; Belongs to the syntaxin family. (171 aa) |
| | LOC102141835 | Ig-like domain-containing protein; Belongs to the MHC class I family. (362 aa) |
| | ANXA11 | Annexin. (506 aa) |
| | TLR7 | Toll-like receptor 7; Belongs to the Toll-like receptor family. (1049 aa) |
| | ATP6V0B | ATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (259 aa) |
| | HVCN1 | Hydrogen voltage gated channel 1. (273 aa) |
| | PIKFYVE | Phosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa) |
| | RAB11FIP1 | RAB11 family interacting protein 1. (1275 aa) |
| | ENSMFAP00000030298 | Ig-like domain-containing protein; Belongs to the MHC class I family. (492 aa) |
| | ANXA3 | Annexin. (323 aa) |
| | NCF4 | Neutrophil cytosolic factor 4. (339 aa) |
| | VIM | Vimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. (466 aa) |
| | STX12 | Syntaxin 12; Belongs to the syntaxin family. (276 aa) |
| | KIF5B | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (964 aa) |
| | RAB11B | Uncharacterized protein. (460 aa) |
| | ENSMFAP00000034437 | Ig-like domain-containing protein; Belongs to the MHC class I family. (394 aa) |
| | ITGAV | Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa) |
| | DMBT1 | Deleted in malignant brain tumors 1. (2145 aa) |
| | SRGAP2 | Uncharacterized protein. (1071 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (891 aa) |
| | INPP5B | Inositol polyphosphate-5-phosphatase B. (829 aa) |
| | RAB32 | Uncharacterized protein. (225 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | ENSMFAP00000036248 | MACPF domain-containing protein. (609 aa) |
| | VAMP8 | Vesicle associated membrane protein 8. (100 aa) |
| | FLNB | Filamin B. (2633 aa) |
| | IRGM | Immunity related GTPase M. (159 aa) |
| | ENSMFAP00000036774 | Ig-like domain-containing protein; Belongs to the MHC class I family. (365 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1117 aa) |
| | NCF1 | Neutrophil cytosolic factor 1. (390 aa) |
| | LTF | Lactotransferrin; Belongs to the transferrin family. (710 aa) |
| | VPS26B | VPS26, retromer complex component B. (336 aa) |
| | RAB31 | RAB31, member RAS oncogene family. (194 aa) |
| | CTSS | Cathepsin S; Belongs to the peptidase C1 family. (331 aa) |
| | DNM2 | Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa) |
| | RAB14 | RAB14, member RAS oncogene family. (215 aa) |
| | GSN | Gelsolin. (784 aa) |
| | ENSMFAP00000041088 | Ig-like domain-containing protein; Belongs to the MHC class I family. (400 aa) |
| | ELANE | Elastase, neutrophil expressed; Belongs to the peptidase S1 family. (264 aa) |
| | ATP6V0A2 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (552 aa) |
| | SNAP23 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | RAB43 | RAB43, member RAS oncogene family. (212 aa) |
| | TRIM14 | Tripartite motif containing 14. (442 aa) |
| | LOC102144128 | TIR domain-containing protein. (1033 aa) |
| | ATP7A | ATPase copper transporting alpha. (1500 aa) |
| | ENSMFAP00000043217 | Ig-like domain-containing protein; Belongs to the MHC class I family. (384 aa) |
| | PIP4P1 | Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P) (By similarity). Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4-bisphosphate, phosphatidylinositol 5- monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate (By similarity). Regulates lysosomal positioning by recruiting JIP4 to lysosomal membranes, thus inducing retrog [...] (277 aa) |
| | SNX3 | Sorting nexin 3. (162 aa) |
| | SYT11 | Uncharacterized protein. (431 aa) |
| | ENSMFAP00000044760 | Uncharacterized protein. (215 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | STXBP3 | Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (592 aa) |
| | RAB11A | RAB11A, member RAS oncogene family. (216 aa) |
