STRINGSTRING
IL1B IL1B ABCD1 ABCD1 AVPR1A AVPR1A MLXIPL MLXIPL APOA5 APOA5 SLC45A3 SLC45A3 AVP AVP ABCD2 ABCD2 NR1H3 NR1H3 CD74 CD74 LPGAT1 LPGAT1 APOC2 APOC2 PTGS2 PTGS2 PLA2G3 PLA2G3 NR1H2 NR1H2 LOC102140140 LOC102140140
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (302 aa)
ABCD1ATP binding cassette subfamily D member 1. (745 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa)
MLXIPLUncharacterized protein. (244 aa)
APOA5Apolipoprotein A5. (366 aa)
SLC45A3Solute carrier family 45 member 3. (553 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa)
ABCD2ATP binding cassette subfamily D member 2. (720 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (453 aa)
CD74CD74 molecule. (294 aa)
LPGAT1Lysophosphatidylglycerol acyltransferase 1. (370 aa)
APOC2Proapolipoprotein C-II; Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. Belongs to the apolipoprotein C2 family. (101 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
PLA2G3Phospholipase A2 group III. (509 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (461 aa)
LOC102140140BHLH domain-containing protein. (412 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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