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| | STIM1 | Stromal interaction molecule 1. (770 aa) |
| | HSPB6 | Heat shock protein family B (small) member 6; Belongs to the small heat shock protein (HSP20) family. (160 aa) |
| | ADAM12 | ADAM metallopeptidase domain 12. (909 aa) |
| | MTDH | Metadherin. (582 aa) |
| | HMOX1 | Uncharacterized protein. (288 aa) |
| | SERPINE1 | Serpin family E member 1; Belongs to the serpin family. (402 aa) |
| | BMPER | BMP binding endothelial regulator. (685 aa) |
| | ITGB8 | Integrin beta; Belongs to the integrin beta chain family. (769 aa) |
| | ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase. (901 aa) |
| | ENSMFAP00000045157 | Uncharacterized protein. (205 aa) |
| | MYDGF | Myeloid derived growth factor. (190 aa) |
| | MINAR1 | Membrane integral NOTCH2 associated receptor 1. (916 aa) |
| | EMC10 | ER membrane protein complex subunit 10. (335 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa) |
| | PLXND1 | Uncharacterized protein. (52 aa) |
| | EPHA1 | EPH receptor A1. (978 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | RAMP2 | Receptor activity modifying protein 2. (149 aa) |
| | GRN | Uncharacterized protein. (593 aa) |
| | SASH1 | SAM and SH3 domain containing 1. (1246 aa) |
| | CCBE1 | Collagen and calcium binding EGF domains 1. (406 aa) |
| | SPRY2 | Protein sprouty homolog 2; May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis. (338 aa) |
| | SEMA4A | Semaphorin 4A; Belongs to the semaphorin family. (760 aa) |
| | GLUL | Glutamine synthetase; Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (By similarity). Its role depends on tissue localization: in the brain, it regulates the levels of toxic ammonia and converts neurotoxic glutamate to harmless glutamine, whereas in the liver, it is one of the enzymes responsible for the removal of ammonia (By similarity). Essential for proliferation of fetal skin fibroblasts. Independently of its glutamine synthetase activity, required for endothelial cell migration during vascular development: acts by regulating [...] (373 aa) |
| | XBP1 | BZIP domain-containing protein. (380 aa) |
| | DDAH1 | Dimethylarginine dimethylaminohydrolase 1. (285 aa) |
| | GPNMB | Glycoprotein nmb. (561 aa) |
| | ENSMFAP00000002594 | Protein kinase domain-containing protein. (351 aa) |
| | CTSH | Cathepsin H; Belongs to the peptidase C1 family. (335 aa) |
| | STAT3 | Signal transducer and activator of transcription. (802 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | CDH5 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (785 aa) |
| | SYNJ2BP | Synaptojanin 2 binding protein. (145 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1196 aa) |
| | JCAD | Junctional cadherin 5 associated. (1356 aa) |
| | ADM | Adrenomedullin. (185 aa) |
| | SIRT6 | Sirtuin 6. (355 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | COL4A2 | Collagen type IV alpha 2 chain. (1724 aa) |
| | TNN | Tenascin N. (1299 aa) |
| | NR2E1 | Nuclear receptor subfamily 2 group E member 1. (385 aa) |
| | CCM2 | CCM2 scaffold protein. (466 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa) |
| | TNFSF12 | TNF superfamily member 12; Belongs to the tumor necrosis factor family. (250 aa) |
| | TNMD | Tenomodulin. (317 aa) |
| | ETS1 | ETS proto-oncogene 1, transcription factor. (485 aa) |
| | AQP1 | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa) |
| | TBXA2R | Thromboxane A2 receptor. (455 aa) |
| | TSPAN12 | Tetraspanin. (305 aa) |
| | PML | Promyelocytic leukemia. (882 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | ENSMFAP00000005508 | Pyruvate kinase; Belongs to the pyruvate kinase family. (332 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | BTG1 | BTG anti-proliferation factor 1. (171 aa) |
| | PTPRM | Protein tyrosine phosphatase receptor type M. (1465 aa) |
| | C5 | Complement C5. (1676 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1072 aa) |
| | COL4A3 | Collagen type IV alpha 3 chain. (1670 aa) |
| | CYBB | Cytochrome b-245 beta chain. (570 aa) |
| | ITGB2 | Integrin beta. (874 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif 9. (1935 aa) |
| | THBS2 | Thrombospondin 2. (1172 aa) |
| | SLC12A2 | Solute carrier family 12 member 2. (1210 aa) |
| | CHRNA7 | Uncharacterized protein. (510 aa) |
| | WARS2 | Tryptophanyl tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (369 aa) |
| | HIPK1 | Homeodomain interacting protein kinase 1. (1210 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa) |
| | PLK2 | Serine/threonine-protein kinase PLK. (685 aa) |
| | MDK | Midkine. (143 aa) |
| | PIK3R6 | Phosphoinositide-3-kinase regulatory subunit 6. (750 aa) |
| | CD34 | CD34 molecule. (385 aa) |
| | FKBPL | TPR_REGION domain-containing protein. (349 aa) |
| | ANGPTL3 | Angiopoietin like 3. (460 aa) |
| | ENSMFAP00000010473 | Uncharacterized protein. (212 aa) |
| | HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (830 aa) |
| | GPR4 | G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (362 aa) |
| | YJEFN3 | YjeF N-terminal domain containing 3. (291 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa) |
| | ALOX5 | Arachidonate 5-lipoxygenase. (674 aa) |
| | PAK4 | Non-specific serine/threonine protein kinase. (600 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | AGO2 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (881 aa) |
| | EMILIN1 | Elastin microfibril interfacer 1. (1016 aa) |
| | PROK1 | Prokineticin 1. (105 aa) |
| | CYSLTR1 | Cysteinyl leukotriene receptor 1. (337 aa) |
| | RRAS | RAS related. (218 aa) |
| | ENSMFAP00000014215 | Anti_prolifrtn domain-containing protein. (161 aa) |
| | APLNR | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa) |
| | FUT1 | L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (366 aa) |
| | RHOB | Ras homolog gene family, member B. (196 aa) |
| | HPSE | Heparanase. (545 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (816 aa) |
| | SPINK5 | Serine peptidase inhibitor, Kazal type 5. (1087 aa) |
| | HSPG2 | Heparan sulfate proteoglycan 2. (4391 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (510 aa) |
| | HMGB1 | High mobility group protein B1; Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functio [...] (221 aa) |
| | SP100 | SP100 nuclear antigen. (863 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (542 aa) |
| | ADGRB2 | Adhesion G protein-coupled receptor B2; Belongs to the G-protein coupled receptor 2 family. (1587 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (645 aa) |
| | CREB3L1 | cAMP responsive element binding protein 3 like 1. (519 aa) |
| | ENSMFAP00000016088 | Uncharacterized protein. (123 aa) |
| | CXCR3 | C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa) |
| | WARS1 | WHEP-TRS domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (475 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | GTF2I | General transcription factor IIi. (998 aa) |
| | APELA | Uncharacterized protein. (54 aa) |
| | SPRED1 | Sprouty related EVH1 domain containing 1. (444 aa) |
| | LOC102125628 | Uncharacterized protein. (139 aa) |
| | GDF2 | Growth differentiation factor 2. (429 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | NPPB | Natriuretic peptide B. (132 aa) |
| | ADGRB1 | Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1566 aa) |
| | VASH1 | Vasohibin 1. (365 aa) |
| | AMOT | Angiomotin. (1099 aa) |
| | PF4 | C-X-C motif chemokine. (101 aa) |
| | HIF1A | Uncharacterized protein. (831 aa) |
| | SPHK1 | Sphingosine kinase 1. (470 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (601 aa) |
| | ITGAX | Integrin subunit alpha X; Belongs to the integrin alpha chain family. (1168 aa) |
| | HRG | Histidine rich glycoprotein. (525 aa) |
| | CXCL13 | C-X-C motif chemokine. (109 aa) |
| | APOH | Uncharacterized protein. (355 aa) |
| | RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) |
| | HTATIP2 | HIV-1 Tat interactive protein 2. (275 aa) |
| | SEMA3E | Semaphorin 3E; Belongs to the semaphorin family. (745 aa) |
| | CD40 | CD40 molecule. (278 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (923 aa) |
| | NPR1 | Guanylate cyclase. (1061 aa) |
| | THBS1 | Thrombospondin 1. (1173 aa) |
| | TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1132 aa) |
| | FOXC1 | Forkhead box C1. (504 aa) |
| | PTGIS | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa) |
| | MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)- containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa) |
| | GATA4 | GATA binding protein 4. (425 aa) |
| | KRIT1 | Uncharacterized protein. (736 aa) |
| | THBS4 | Thrombospondin 4. (961 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (314 aa) |
| | HK2 | Hexokinase 2. (913 aa) |
| | RNH1 | Ribonuclease/angiogenin inhibitor 1. (456 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa) |
| | FOXJ2 | Forkhead box J2. (574 aa) |
| | KLF4 | Testis cDNA clone: QtsA-19426, similar to human Kruppel-like factor 4 (gut) (KLF4). (479 aa) |
| | ISL1 | ISL LIM homeobox 1. (349 aa) |
| | ABCC8 | ATP binding cassette subfamily C member 8. (1582 aa) |
| | ADGRA2 | Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1340 aa) |
| | JMJD8 | Jumonji domain containing 8. (322 aa) |
| | GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) |
| | RGCC | Regulator of cell cycle. (137 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (302 aa) |
| | FOXO4 | Forkhead box O4. (505 aa) |
| | CNMD | Chondromodulin. (333 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | SARS1 | Serine--tRNA ligase, cytoplasmic; Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). In the nucleus, binds to the VEGFA core promoter and prevents MYC binding and transcriptional activation by MYC. Recruits SIRT2 to the VEGFA promoter, promoting deacetylation of histone H4 at 'Lys-16' (H4K16 [...] (491 aa) |
| | HMGA2 | High mobility group AT-hook 2. (147 aa) |
| | ERAP1 | Aminopeptidase. (941 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa) |
| | RECK | Reversion inducing cysteine rich protein with kazal motifs. (962 aa) |
| | SULF1 | Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (869 aa) |
| | GHRL | Ghrelin and obestatin prepropeptide. (117 aa) |
| | NAXE | NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (288 aa) |
| | PDE3B | Phosphodiesterase. (1117 aa) |
| | CD160 | CD160 molecule. (233 aa) |
| | GAB1 | GRB2 associated binding protein 1. (751 aa) |
| | CX3CR1 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (386 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (409 aa) |
| | RLN2 | Relaxin 2. (158 aa) |
| | ENSMFAP00000025660 | Uncharacterized protein. (342 aa) |
| | BRCA1 | Uncharacterized protein. (1884 aa) |
| | SERPINF1 | SERPIN domain-containing protein; Belongs to the serpin family. (406 aa) |
| | CELA1 | Chymotrypsin-like elastase family member 1; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily. (261 aa) |
| | PGF | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (200 aa) |
| | VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa) |
| | PKM | Pyruvate kinase; Belongs to the pyruvate kinase family. (556 aa) |
| | ANGPT2 | Angiopoietin 2. (496 aa) |
| | GATA6 | GATA binding protein 6. (557 aa) |
| | C3 | Complement C3. (1663 aa) |
| | IL17F | Interleukin 17F. (163 aa) |
| | ENSMFAP00000027000 | Pyruvate kinase; Belongs to the pyruvate kinase family. (142 aa) |
| | PDCD10 | Programmed cell death protein 10. (212 aa) |
| | TEK | TEK receptor tyrosine kinase. (1124 aa) |
| | EPHA2 | Ephrin type-A receptor 2; Receptor tyrosine kinase which binds promiscuously membrane- bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin- A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DS [...] (1036 aa) |
| | STAB1 | Stabilin 1. (2568 aa) |
| | SP1 | Sp1 transcription factor. (786 aa) |
| | HSPB1 | SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (205 aa) |
| | ECSCR | Uncharacterized protein. (205 aa) |
| | HOXA5 | Homeobox A5. (270 aa) |
| | LRG1 | Leucine rich alpha-2-glycoprotein 1. (347 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (816 aa) |
| | CCL24 | C-C motif chemokine ligand 24. (119 aa) |
| | VASH2 | Vasohibin 2. (355 aa) |
| | F3 | Coagulation factor III, tissue factor. (296 aa) |
| | ANGPT4 | Angiopoietin 4. (503 aa) |
| | DAB2IP | DAB2 interacting protein. (1153 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (353 aa) |
| | ITGA5 | Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1098 aa) |
| | TBC1D31 | Uncharacterized protein. (1067 aa) |
| | CEACAM1 | Uncharacterized protein. (525 aa) |
| | EMILIN2 | Elastin microfibril interfacer 2. (1080 aa) |
| | CCR3 | C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. (376 aa) |
| | ADM2 | Adrenomedullin 2. (148 aa) |
| | STAT1 | Signal transducer and activator of transcription. (758 aa) |
| | TIE1 | Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa) |
| | IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa) |
| | ENPP2 | Ectonucleotide pyrophosphatase/phosphodiesterase 2. (915 aa) |
| | AGO1 | Argonaute RISC component 1; Belongs to the argonaute family. (857 aa) |
| | HYAL1 | Hyaluronidase. (435 aa) |
| | RTN4 | Reticulon. (1193 aa) |
| | ANXA3 | Annexin. (323 aa) |
| | HHEX | Hematopoietically expressed homeobox. (270 aa) |
| | TJP1 | Tight junction protein 1; Belongs to the MAGUK family. (1767 aa) |
| | ANGPTL4 | Angiopoietin like 4. (239 aa) |
| | JAK1 | Tyrosine-protein kinase. (1159 aa) |
| | CHI3L1 | Chitinase 3 like 1; Belongs to the glycosyl hydrolase 18 family. (405 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa) |
| | ISM1 | Isthmin 1. (418 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (420 aa) |
| | ADGRB3 | Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family. (1522 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa) |
| | NIBAN2 | Niban apoptosis regulator 2. (746 aa) |
| | SMOC2 | SPARC related modular calcium binding 2. (330 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | PPP1R16B | Protein phosphatase 1 regulatory subunit 16B. (465 aa) |
| | FOXC2 | Forkhead box C2. (487 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | JUP | Junction plakoglobin. (745 aa) |
| | RAPGEF3 | Rap guanine nucleotide exchange factor 3. (923 aa) |
| | ZNF304 | Zinc finger protein 304. (706 aa) |
| | ENG | Endoglin. (555 aa) |
| | HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (788 aa) |
| | DCN | Decorin; May affect the rate of fibrils formation. (359 aa) |
| | SMAD1 | Mothers against decapentaplegic homolog. (465 aa) |
| | AGGF1 | Uncharacterized protein. (710 aa) |
| | CXCL10 | C-X-C motif chemokine. (98 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | GATA2 | GATA binding protein 2. (480 aa) |
| | SPARC | Secreted protein acidic and cysteine rich. (303 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (295 aa) |
| | GHSR | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa) |
| | SEMA5A | Semaphorin 5A. (1074 aa) |
| | PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa) |
| | EPN2 | Epsin 2. (641 aa) |
| | SIRT1 | Sirtuin 1. (743 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa) |
| | NF1 | Neurofibromin 1. (2849 aa) |
| | EPN1 | Epsin 1. (662 aa) |
| | NFE2L2 | Nuclear factor, erythroid 2 like 2. (606 aa) |
| | EFNA1 | Ephrin A1; Belongs to the ephrin family. (205 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1406 aa) |
| | ENSMFAP00000041212 | Uncharacterized protein; Belongs to the glutamine synthetase family. (196 aa) |
| | SEMA6A | Semaphorin 6A; Belongs to the semaphorin family. (1047 aa) |
| | NODAL | Nodal growth differentiation factor. (347 aa) |
| | RHOJ | Uncharacterized protein. (214 aa) |
| | NINJ1 | Ninjurin 1. (152 aa) |
| | ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif 1. (967 aa) |
| | ACVRL1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (788 aa) |
| | EGLN1 | Egl-9 family hypoxia inducible factor 1. (418 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (920 aa) |
| | ENSMFAP00000042558 | Uncharacterized protein. (170 aa) |
| | ENSMFAP00000042604 | Pyruvate kinase; Belongs to the pyruvate kinase family. (455 aa) |
| | ECM1 | Extracellular matrix protein 1. (540 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa) |
| | ENSMFAP00000043489 | Pyruvate kinase; Belongs to the pyruvate kinase family. (525 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T- cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. [FasL intr [...] (280 aa) |
