STRINGSTRING
ENSMFAP00000001080 ENSMFAP00000001080 ENSMFAP00000001834 ENSMFAP00000001834 SNCB SNCB SNCG SNCG SYNJ2 SYNJ2 DNM3 DNM3 SYT2 SYT2 ARF6 ARF6 CDK5 CDK5 ENSMFAP00000005493 ENSMFAP00000005493 AP3B2 AP3B2 VAMP1 VAMP1 STX1A STX1A PACSIN1 PACSIN1 SYNJ1 SYNJ1 ENSMFAP00000013586 ENSMFAP00000013586 KIAA1109 KIAA1109 FCHO2 FCHO2 DNM1 DNM1 DENND1A DENND1A CANX CANX BIN1 BIN1 NOSTRIN NOSTRIN ACTB ACTB AP2B1 AP2B1 AP3D1 AP3D1 GAK GAK SH3GL2 SH3GL2 SH3GL1 SH3GL1 ITSN1 ITSN1 DNAJC6 DNAJC6 PIP5K1C PIP5K1C AP3M2 AP3M2 SNAP91 SNAP91 ITSN2 ITSN2 ENSMFAP00000030029 ENSMFAP00000030029 SCRIB SCRIB NLGN2 NLGN2 NLGN1 NLGN1 RAB27B RAB27B SYT5 SYT5 BTBD8 BTBD8 AP3S1 AP3S1 SYT8 SYT8 PICALM PICALM SYP SYP SH3GL3 SH3GL3 DNM2 DNM2 ENSMFAP00000040574 ENSMFAP00000040574 OPHN1 OPHN1 LRRC1 LRRC1 SYNPR SYNPR STON2 STON2 AMPH AMPH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMFAP00000001080Uncharacterized protein; Belongs to the actin family. (354 aa)
ENSMFAP00000001834COesterase domain-containing protein. (221 aa)
SNCBBeta-synuclein; Belongs to the synuclein family. (134 aa)
SNCGGamma-synuclein; Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity); Belongs to the synuclein family. (127 aa)
SYNJ2Synaptojanin 2. (1390 aa)
DNM3Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (869 aa)
SYT2Synaptotagmin 2. (419 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (148 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
ENSMFAP00000005493COesterase domain-containing protein. (295 aa)
AP3B2AP-3 complex subunit beta. (1101 aa)
VAMP1Vesicle associated membrane protein 1. (118 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (288 aa)
PACSIN1Protein kinase C and casein kinase substrate in neurons 1. (444 aa)
SYNJ1Synaptojanin 1. (1548 aa)
ENSMFAP00000013586Uncharacterized protein; Belongs to the actin family. (257 aa)
KIAA1109KIAA1109. (5058 aa)
FCHO2FCH domain only 2. (815 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
DENND1ADENN domain containing 1A. (915 aa)
CANXCalnexin. (592 aa)
BIN1Bridging integrator 1. (451 aa)
NOSTRINNitric oxide synthase trafficking. (562 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (379 aa)
AP2B1AP complex subunit beta. (951 aa)
AP3D1AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1215 aa)
GAKCyclin G associated kinase. (1311 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (341 aa)
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (320 aa)
ITSN1Intersectin 1. (1625 aa)
DNAJC6DnaJ heat shock protein family (Hsp40) member C6. (970 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (708 aa)
AP3M2AP-3 complex subunit mu-2. (418 aa)
SNAP91Synaptosome associated protein 91. (907 aa)
ITSN2Intersectin 2. (1697 aa)
ENSMFAP00000030029BAR domain-containing protein. (320 aa)
SCRIBScribble planar cell polarity protein. (1662 aa)
NLGN2Neuroligin 2. (849 aa)
NLGN1Neuroligin 1. (823 aa)
RAB27BRAB27B, member RAS oncogene family. (218 aa)
SYT5Brain cDNA, clone: QccE-17821, similar to human synaptotagmin V (SYT5). (386 aa)
BTBD8BTB domain containing 8. (1411 aa)
AP3S1Adaptor related protein complex 3 subunit sigma 1. (193 aa)
SYT8Synaptotagmin 8. (387 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (686 aa)
SYPSynaptophysin. (313 aa)
SH3GL3Uncharacterized protein. (354 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
ENSMFAP00000040574Uncharacterized protein. (130 aa)
OPHN1Oligophrenin 1. (802 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
SYNPRSynaptoporin. (285 aa)
STON2Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family. (955 aa)
AMPHAmphiphysin. (694 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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