STRINGSTRING
FGF9 FGF9 EYA4 EYA4 USH1G USH1G KCNK2 KCNK2 FGFR2 FGFR2 TBX2 TBX2 ZIC1 ZIC1 SPRY2 SPRY2 SLITRK6 SLITRK6 LOC102129056 LOC102129056 PCDH15 PCDH15 PDGFRB PDGFRB CCM2 CCM2 SLC17A8 SLC17A8 PLS1 PLS1 MYO3B MYO3B TCAP TCAP TTC8 TTC8 MKS1 MKS1 TGFB2 TGFB2 FREM2 FREM2 ATP8B1 ATP8B1 SLC26A5 SLC26A5 USH1C USH1C STOX1 STOX1 BMP4 BMP4 LRP10 LRP10 TRIP11 TRIP11 FZD6 FZD6 PJVK PJVK PHOX2B PHOX2B ESRRB ESRRB SLC4A7 SLC4A7 GABRA5 GABRA5 NEUROD1 NEUROD1 LOC102144923 LOC102144923 CEBPD CEBPD FOXI1 FOXI1 GJB6 GJB6 ATOH1 ATOH1 NEUROG1 NEUROG1 TTC39C TTC39C TSKU TSKU MCM2 MCM2 TGFB3 TGFB3 TRIOBP TRIOBP DUOX2 DUOX2 CEBPA CEBPA ATP8B3 ATP8B3 EYA1 EYA1 GRXCR2 GRXCR2 ENSMFAP00000015614 ENSMFAP00000015614 CLRN2 CLRN2 GLI3 GLI3 COL2A1 COL2A1 KCNK3 KCNK3 SDC4 SDC4 OTX1 OTX1 SOBP SOBP GBX2 GBX2 CXCL14 CXCL14 BLOC1S5 BLOC1S5 HEY2 HEY2 LGR5 LGR5 CCNA2 CCNA2 ENSMFAP00000036760 ENSMFAP00000036760 WNT1 WNT1 HOXA1 HOXA1 KCNQ4 KCNQ4 HPCA HPCA CYS1 CYS1 HMX2 HMX2 WNT5A WNT5A LHFPL5 LHFPL5 HESX1 HESX1 ADAM10 ADAM10 ENSMFAP00000034570 ENSMFAP00000034570 FGF8 FGF8 FGF10 FGF10 WHRN WHRN DLX6 DLX6 EPHB2 EPHB2 CDH23 CDH23 MPV17 MPV17 TPRN TPRN CHRNA9 CHRNA9 CYTL1 CYTL1 TMIE TMIE ENSMFAP00000032598 ENSMFAP00000032598 EPHA4 EPHA4 ATP8A2 ATP8A2 SHH SHH ENSMFAP00000031517 ENSMFAP00000031517 TGFB1 TGFB1 MYO3A MYO3A LOC102117151 LOC102117151 GATA3 GATA3 IFT88 IFT88 ZEB1 ZEB1 GRHL3 GRHL3 ATP6V1B1 ATP6V1B1 SCRIB SCRIB PROX1 PROX1 TMC1 TMC1 CHD7 CHD7 SIX4 SIX4 ALDH1A3 ALDH1A3 STRC STRC WNT3A WNT3A GSDME GSDME LRIG3 LRIG3 TBX1 TBX1 CLRN1 CLRN1 IFT27 IFT27 PLPPR4 PLPPR4 MYO7A MYO7A CTHRC1 CTHRC1 PTK7 PTK7 FZD3 FZD3 BCR BCR OTOP1 OTOP1 PTPRQ PTPRQ HPCAL1 HPCAL1 BMP2 BMP2 KCNQ1 KCNQ1 USH2A USH2A PVALB PVALB DCHS1 DCHS1 RPGRIP1L RPGRIP1L FGF20 FGF20 DLX5 DLX5 DVL1 DVL1 FRZB FRZB MAPKAPK2 MAPKAPK2 LRIG1 LRIG1 WDPCP WDPCP MCOLN3 MCOLN3 AHI1 AHI1 JAG1 JAG1 CECR2 CECR2 IFT20 IFT20 ANP32B ANP32B ITGA8 ITGA8 ADGRV1 ADGRV1 SIX1 SIX1 CHRNA10 CHRNA10 PRRX1 PRRX1 CDKN1B CDKN1B NOX3 NOX3 NTN1 NTN1 PDZD7 PDZD7 GRXCR1 GRXCR1 JAG2 JAG2 C1QTNF5 C1QTNF5 POU4F3 POU4F3 FZD2 FZD2 INSIG1 INSIG1 GATA2 GATA2 C1QB C1QB REST REST SEC24B SEC24B CEP290 CEP290 PTPN11 PTPN11 DCANP1 DCANP1 LOC102136364 LOC102136364 MYO6 MYO6 ROR1 ROR1 SLC44A4 SLC44A4 COL11A1 COL11A1 HPN HPN SOD1 SOD1 HMX3 HMX3 ATG5 ATG5 PAX2 PAX2 TBX18 TBX18 HOXA13 HOXA13 MYO15B MYO15B TFAP2A TFAP2A ATG4B ATG4B LRRC1 LRRC1 LIN7A LIN7A LHX3 LHX3 GABRB2 GABRB2 TSHR TSHR DLL1 DLL1 NAGLU NAGLU ENSMFAP00000043772 ENSMFAP00000043772 OTOL1 OTOL1 MYO15A MYO15A SOX9 SOX9 TBX3 TBX3 DVL2 DVL2 BMPER BMPER FOXG1 FOXG1 NOTCH1 NOTCH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
EYA4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (639 aa)
USH1GUSH1 protein network component sans. (461 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
FGFR2Fibroblast growth factor receptor. (810 aa)
TBX2T-box transcription factor 2. (639 aa)
ZIC1Zic family member 1. (488 aa)
SPRY2Protein sprouty homolog 2; May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis. (338 aa)
SLITRK6SLIT and NTRK like family member 6. (841 aa)
LOC102129056Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase. (473 aa)
PCDH15Protocadherin related 15. (1960 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
CCM2CCM2 scaffold protein. (466 aa)
SLC17A8Solute carrier family 17 member 8. (589 aa)
PLS1Plastin 1. (629 aa)
MYO3BMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1350 aa)
TCAPUncharacterized protein. (167 aa)
TTC8Tetratricopeptide repeat domain 8. (531 aa)
MKS1MKS transition zone complex subunit 1. (559 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
FREM2FRAS1 related extracellular matrix 2. (3170 aa)
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1251 aa)
SLC26A5Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (748 aa)
USH1CUSH1 protein network component harmonin. (899 aa)
STOX1Storkhead box 1. (885 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
LRP10LDL receptor related protein 10. (714 aa)
TRIP11Thyroid hormone receptor interactor 11. (1981 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
PJVKPejvakin. (352 aa)
PHOX2BPaired like homeobox 2B. (314 aa)
ESRRBEstrogen related receptor beta. (438 aa)
SLC4A7Anion exchange protein. (1259 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
LOC102144923Uncharacterized protein; Belongs to the parvalbumin family. (136 aa)
CEBPDCCAAT/enhancer-binding protein. (265 aa)
FOXI1Forkhead box I1. (378 aa)
GJB6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (261 aa)
ATOH1Atonal bHLH transcription factor 1. (354 aa)
NEUROG1Neurogenin 1. (237 aa)
TTC39CTetratricopeptide repeat domain 39C. (583 aa)
TSKUTsukushi, small leucine rich proteoglycan. (353 aa)
MCM2DNA helicase; Belongs to the MCM family. (900 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
TRIOBPPH domain-containing protein. (591 aa)
DUOX2Dual oxidase 2. (1546 aa)
CEBPACCAAT enhancer binding protein alpha. (198 aa)
ATP8B3Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1307 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
GRXCR2Glutaredoxin and cysteine rich domain containing 2. (248 aa)
ENSMFAP00000015614Uncharacterized protein. (506 aa)
CLRN2Clarin 2. (232 aa)
GLI3GLI family zinc finger 3. (1579 aa)
COL2A1Collagen type II alpha 1 chain. (1502 aa)
KCNK3Potassium channel subfamily K member. (394 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa)
OTX1Orthodenticle homeobox 1. (354 aa)
SOBPSine oculis binding protein homolog. (874 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
CXCL14C-X-C motif chemokine ligand 14. (111 aa)
BLOC1S5Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). (187 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
ENSMFAP00000036760Uncharacterized protein. (124 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
HOXA1Homeobox A1. (335 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (652 aa)
HPCAHippocalcin. (193 aa)
CYS1Cystin 1. (130 aa)
HMX2H6 family homeobox 2. (273 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
LHFPL5LHFPL tetraspan subfamily member 5. (272 aa)
HESX1HESX homeobox 1. (185 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
ENSMFAP00000034570Uncharacterized protein. (265 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
WHRNWhirlin. (907 aa)
DLX6Distal-less homeobox 6. (230 aa)
EPHB2Uncharacterized protein. (468 aa)
CDH23Cadherin related 23. (3359 aa)
MPV17Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (191 aa)
TPRNPhostensin domain-containing protein. (431 aa)
CHRNA9Cholinergic receptor nicotinic alpha 9 subunit. (479 aa)
CYTL1Cytokine like 1. (136 aa)
TMIETransmembrane inner ear. (154 aa)
ENSMFAP00000032598LRRcap domain-containing protein. (217 aa)
EPHA4EPH receptor A4. (986 aa)
ATP8A2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1164 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
ENSMFAP00000031517Uncharacterized protein. (262 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
MYO3AMyosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1623 aa)
LOC102117151Uncharacterized protein; Belongs to the parvalbumin family. (109 aa)
GATA3GATA binding protein 3. (444 aa)
IFT88Intraflagellar transport 88. (824 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1127 aa)
GRHL3Grainyhead like transcription factor 3. (626 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
SCRIBScribble planar cell polarity protein. (1662 aa)
PROX1Prospero homeobox 1. (737 aa)
TMC1Transmembrane channel-like protein. (761 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2998 aa)
SIX4SIX homeobox 4. (780 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
STRCStereocilin. (1768 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
GSDMEGasdermin E. (495 aa)
LRIG3Leucine rich repeats and immunoglobulin like domains 3. (1119 aa)
TBX1T-box transcription factor 1. (441 aa)
CLRN1Clarin 1. (245 aa)
IFT27Intraflagellar transport 27. (186 aa)
PLPPR4Phospholipid phosphatase related 4. (763 aa)
MYO7AMyosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2215 aa)
CTHRC1Collagen triple helix repeat containing 1. (243 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1078 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
BCRBCR activator of RhoGEF and GTPase. (1227 aa)
OTOP1Otopetrin 1. (610 aa)
PTPRQProtein tyrosine phosphatase receptor type Q. (2332 aa)
HPCAL1Hippocalcin like 1. (193 aa)
BMP2Bone morphogenetic protein 2. (544 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (644 aa)
USH2AUsherin. (5210 aa)
PVALBParvalbumin; Belongs to the parvalbumin family. (110 aa)
DCHS1Dachsous cadherin-related 1. (3295 aa)
RPGRIP1LRPGRIP1 like. (1331 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
DLX5Distal-less homeobox 5. (289 aa)
DVL1Dishevelled segment polarity protein 1. (673 aa)
FRZBFrizzled related protein. (325 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (381 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1088 aa)
WDPCPWD repeat containing planar cell polarity effector. (731 aa)
MCOLN3Mucolipin 3. (553 aa)
AHI1Abelson helper integration site 1. (1196 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
CECR2CECR2 histone acetyl-lysine reader. (1420 aa)
IFT20Uncharacterized protein. (156 aa)
ANP32BAcidic nuclear phosphoprotein 32 family member B. (251 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
ADGRV1Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family. (6306 aa)
SIX1SIX homeobox 1. (284 aa)
CHRNA10Cholinergic receptor nicotinic alpha 10 subunit. (450 aa)
PRRX1Paired related homeobox 1. (245 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
NOX3NADPH oxidase 3. (568 aa)
NTN1Netrin 1. (598 aa)
PDZD7PDZ domain containing 7. (1030 aa)
GRXCR1Glutaredoxin and cysteine rich domain containing 1. (290 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1075 aa)
C1QTNF5C1q and TNF related 5. (243 aa)
POU4F3POU domain protein. (568 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (562 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa)
GATA2GATA binding protein 2. (480 aa)
C1QBComplement C1q B chain. (253 aa)
RESTRE1 silencing transcription factor. (1095 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1277 aa)
CEP290Centrosomal protein 290. (2461 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
DCANP1Dendritic cell associated nuclear protein. (197 aa)
LOC102136364Uncharacterized protein. (291 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1290 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (923 aa)
SLC44A4Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family. (710 aa)
COL11A1Collagen type XI alpha 1 chain. (1818 aa)
HPNHepsin; Belongs to the peptidase S1 family. (471 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
HMX3H6 family homeobox 3. (357 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
PAX2Paired box 2. (417 aa)
TBX18T-box transcription factor 18. (607 aa)
HOXA13Homeobox A13. (228 aa)
MYO15BMyosin XVB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3003 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (393 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
LHX3LIM homeobox 3. (402 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (743 aa)
ENSMFAP00000043772Uncharacterized protein. (457 aa)
OTOL1Otolin 1. (470 aa)
MYO15AMyosin XVA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3510 aa)
SOX9SRY-box transcription factor 9. (509 aa)
TBX3T-box transcription factor 3. (743 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
BMPERBMP binding endothelial regulator. (685 aa)
FOXG1Forkhead box G1. (489 aa)
NOTCH1Notch receptor 1. (2556 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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