STRINGSTRING
TGFB1 TGFB1 MYL3 MYL3 FGFR2 FGFR2 ZFPM2 ZFPM2 MYL10 MYL10 EDNRA EDNRA FOXH1 FOXH1 RYR2 RYR2 TGFBR3 TGFBR3 NRG1 NRG1 TGFB2 TGFB2 HEG1 HEG1 BMPR1A BMPR1A TNNI1 TNNI1 PKP2 PKP2 MYH7 MYH7 NOG NOG PTCD2 PTCD2 DSP DSP HEY2 HEY2 FOXC1 FOXC1 ISL1 ISL1 SMAD7 SMAD7 TNNI3 TNNI3 TGFBR1 TGFBR1 LRP2 LRP2 CHD7 CHD7 PROX1 PROX1 DLL4 DLL4 MYL2 MYL2 SMAD4 SMAD4 TNNT2 TNNT2 FOXC2 FOXC2 MYBPC3 MYBPC3 ENG ENG TNNC1 TNNC1 NKX2-5 NKX2-5 BMP10 BMP10 MED1 MED1 COL11A1 COL11A1 HAND1 HAND1 MYH6 MYH6 NOTCH1 NOTCH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
MYL3Myosin light chain 3. (225 aa)
FGFR2Fibroblast growth factor receptor. (810 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
MYL10Myosin light chain 10. (177 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
FOXH1Forkhead box H1. (366 aa)
RYR2Ryanodine receptor 2. (4943 aa)
TGFBR3Transforming growth factor beta receptor 3. (851 aa)
NRG1Neuregulin 1. (713 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
HEG1Heart development protein with EGF like domains 1. (1285 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
TNNI1Troponin I1, slow skeletal type. (187 aa)
PKP2Plakophilin 2. (886 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
PTCD2Pentatricopeptide repeat domain 2. (388 aa)
DSPDesmoplakin. (2871 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
FOXC1Forkhead box C1. (504 aa)
ISL1ISL LIM homeobox 1. (349 aa)
SMAD7Mothers against decapentaplegic homolog. (495 aa)
TNNI3Troponin I3, cardiac type. (210 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
LRP2LDL receptor related protein 2. (4655 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2998 aa)
PROX1Prospero homeobox 1. (737 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
MYL2Myosin light chain 2. (166 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TNNT2Troponin T2, cardiac type. (301 aa)
FOXC2Forkhead box C2. (487 aa)
MYBPC3Myosin binding protein C, cardiac. (1274 aa)
ENGEndoglin. (555 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
NKX2-5NK2 homeobox 5. (324 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa)
COL11A1Collagen type XI alpha 1 chain. (1818 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
NOTCH1Notch receptor 1. (2556 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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