STRINGSTRING
WNT9B WNT9B ENSMFAP00000000815 ENSMFAP00000000815 TBX2 TBX2 DLG1 DLG1 FRAS1 FRAS1 FOXE1 FOXE1 ALX4 ALX4 PAK1IP1 PAK1IP1 TGFBR3 TGFBR3 ITGB6 ITGB6 TGFB2 TGFB2 BMPR1A BMPR1A TSHZ1 TSHZ1 TIPARP TIPARP MEOX2 MEOX2 FOXF2 FOXF2 CSRNP1 CSRNP1 SNAI1 SNAI1 COL11A2 COL11A2 SOX11 SOX11 TGFB3 TGFB3 G7PFU7_MACFA G7PFU7_MACFA CLDN5 CLDN5 OSR2 OSR2 WFIKKN1 WFIKKN1 SUMO1 SUMO1 GLI3 GLI3 COL2A1 COL2A1 ASPH ASPH SOS1 SOS1 SKI SKI PRRX1 PRRX1 ANP32B ANP32B TMEM107 TMEM107 WDPCP WDPCP GABRB3 GABRB3 DLX5 DLX5 SATB2 SATB2 WNT11 WNT11 MSC MSC DHRS3 DHRS3 VAX1 VAX1 WNT7A WNT7A PYGO2 PYGO2 TGFBR1 TGFBR1 WNT8A WNT8A ENSMFAP00000027910 ENSMFAP00000027910 TBX1 TBX1 WNT3A WNT3A WFIKKN2 WFIKKN2 SUMO1-2 SUMO1-2 SMAD2 SMAD2 CHD7 CHD7 NPRL3 NPRL3 BCOR BCOR BBS7 BBS7 ARID5B ARID5B BNC2 BNC2 SHH SHH EPHB3 EPHB3 SMAD4 SMAD4 ENSMFAP00000032598 ENSMFAP00000032598 LEF1 LEF1 EPHB2 EPHB2 PKDCC PKDCC DLX6 DLX6 TGFBR2 TGFBR2 WNT5A WNT5A ENSMFAP00000036744 ENSMFAP00000036744 JAG2 JAG2 INHBA INHBA FZD2 FZD2 CPLANE1 CPLANE1 INSIG1 INSIG1 TBC1D32 TBC1D32 HAND2 HAND2 SNAI2 SNAI2 ACVR2B ACVR2B PLEKHA1 PLEKHA1 TCF21 TCF21 IFT172 IFT172 TFAP2A TFAP2A OSR1 OSR1 MSX1 MSX1 LOXL3 LOXL3 LRRC32 LRRC32 IRF6 IRF6 TBX3 TBX3 GDF11 GDF11 ITGB8 ITGB8 INTU INTU SGPL1 SGPL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
ENSMFAP00000000815Small ubiquitin-related modifier. (121 aa)
TBX2T-box transcription factor 2. (639 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (938 aa)
FRAS1Fraser extracellular matrix complex subunit 1. (4012 aa)
FOXE1Forkhead box E1. (373 aa)
ALX4ALX homeobox 4. (409 aa)
PAK1IP1PAK1 interacting protein 1. (392 aa)
TGFBR3Transforming growth factor beta receptor 3. (851 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
TSHZ1Teashirt zinc finger homeobox 1. (1097 aa)
TIPARPTCDD inducible poly(ADP-ribose) polymerase. (657 aa)
MEOX2Mesenchyme homeobox 2. (303 aa)
FOXF2Forkhead box F2. (411 aa)
CSRNP1Cysteine and serine rich nuclear protein 1. (593 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
COL11A2Collagen type XI alpha 2 chain. (1736 aa)
SOX11Transcription factor SOX. (441 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
G7PFU7_MACFASmall ubiquitin-related modifier. (101 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
OSR2Odd-skipped related transciption factor 2. (402 aa)
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa)
SUMO1Ubiquitin-like domain-containing protein. (146 aa)
GLI3GLI family zinc finger 3. (1579 aa)
COL2A1Collagen type II alpha 1 chain. (1502 aa)
ASPHAspartate beta-hydroxylase. (762 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1314 aa)
SKISKI proto-oncogene. (681 aa)
PRRX1Paired related homeobox 1. (245 aa)
ANP32BAcidic nuclear phosphoprotein 32 family member B. (251 aa)
TMEM107Transmembrane protein 107. (146 aa)
WDPCPWD repeat containing planar cell polarity effector. (731 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (529 aa)
DLX5Distal-less homeobox 5. (289 aa)
SATB2DNA-binding protein SATB. (733 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
MSCMusculin. (206 aa)
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
VAX1Ventral anterior homeobox 1. (334 aa)
WNT7AProtein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal [...] (349 aa)
PYGO2Pygopus family PHD finger 2. (408 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
ENSMFAP00000027910Rad60-SLD domain-containing protein. (81 aa)
TBX1T-box transcription factor 1. (441 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (576 aa)
SUMO1-2Rad60-SLD domain-containing protein. (67 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2998 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (548 aa)
BCORBCL6 corepressor. (1755 aa)
BBS7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
ARID5BAT-rich interaction domain 5B. (1188 aa)
BNC2Basonuclin 2. (1121 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
EPHB3EPH receptor B3. (1008 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ENSMFAP00000032598LRRcap domain-containing protein. (217 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
EPHB2Uncharacterized protein. (468 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (432 aa)
DLX6Distal-less homeobox 6. (230 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
ENSMFAP00000036744Uncharacterized protein. (90 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1075 aa)
INHBAInhibin subunit beta A. (426 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (562 aa)
CPLANE1Ciliogenesis and planar polarity effector 1. (3200 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa)
TBC1D32TBC1 domain family member 32. (1319 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
SNAI2Uncharacterized protein. (268 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (518 aa)
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)
TCF21Transcription factor 21. (179 aa)
IFT172Intraflagellar transport 172. (1749 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
MSX1Msh homeobox 1. (303 aa)
LOXL3Lysyl oxidase like 3. (753 aa)
LRRC32Leucine rich repeat containing 32. (662 aa)
IRF6Interferon regulatory factor 6. (467 aa)
TBX3T-box transcription factor 3. (743 aa)
GDF11Growth differentiation factor 11. (342 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (769 aa)
INTUInturned planar cell polarity protein. (942 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (560 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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