STRINGSTRING
CRHR2 CRHR2 LRRTM2 LRRTM2 SHANK3 SHANK3 RGS14 RGS14 SLC1A1 SLC1A1 PRKCZ PRKCZ MPP2 MPP2 PTK2B PTK2B PTEN PTEN RASGRF2 RASGRF2 GRIN2A GRIN2A NPTN NPTN SYT12 SYT12 STX4 STX4 GRIN2C GRIN2C NTRK2 NTRK2 SERPINE2 SERPINE2 GFAP GFAP MECP2 MECP2 PRRT1 PRRT1 SLC24A2 SLC24A2 GRIN2D GRIN2D SHANK2 SHANK2 NOG NOG MPP6 MPP6 LRRTM1 LRRTM1 GRIN2B GRIN2B LOC102136620 LOC102136620 PLK2 PLK2 BRAF BRAF SNAP47 SNAP47 NFATC4 NFATC4 RELN RELN SLC8A3 SLC8A3 GIP GIP ARC ARC MAPK1 MAPK1 NR2E1 NR2E1 SNAP25 SNAP25 SLC8A2 SLC8A2 TNR TNR SLC24A1 SLC24A1 TSHZ3 TSHZ3 STX3 STX3 ITPR3 ITPR3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (431 aa)
LRRTM2Leucine rich repeat transmembrane neuronal 2. (516 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1596 aa)
RGS14Regulator of G protein signaling 14. (566 aa)
SLC1A1Solute carrier family 1 member 1. (524 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (583 aa)
MPP2Membrane palmitoylated protein 2; Belongs to the MAGUK family. (537 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
RASGRF2Ras protein specific guanine nucleotide releasing factor 2. (1237 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
NPTNNeuroplastin. (398 aa)
SYT12Synaptotagmin 12. (421 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (171 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1242 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (517 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)- containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
PRRT1Proline rich transmembrane protein 1. (306 aa)
SLC24A2Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (664 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1062 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1742 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
MPP6Uncharacterized protein; Belongs to the MAGUK family. (582 aa)
LRRTM1Leucine rich repeat transmembrane neuronal 1. (522 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
LOC102136620Uncharacterized protein. (64 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (762 aa)
SNAP47Synaptosome associated protein 47. (463 aa)
NFATC4Nuclear factor of activated T cells 4. (918 aa)
RELNReelin. (3464 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
GIPGastric inhibitory polypeptide. (153 aa)
ARCActivity regulated cytoskeleton associated protein. (471 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (753 aa)
TNRTenascin R. (1358 aa)
SLC24A1Solute carrier family 24 member 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (912 aa)
TSHZ3Teashirt zinc finger homeobox 3. (1081 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (302 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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