STRINGSTRING
NOTCH1 NOTCH1 TBX3 TBX3 HEY1 HEY1 MSX1 MSX1 EFNA1 EFNA1 SNAI2 SNAI2 ENG ENG FGF8 FGF8 RTN4 RTN4 SMAD4 SMAD4 HEYL HEYL TGFBR1 TGFBR1 WNT2 WNT2 ADAM15 ADAM15 BMP2 BMP2 HAS2 HAS2 HEY2 HEY2 WNT16 WNT16 TMEM100 TMEM100 SPRY1 SPRY1 SNAI1 SNAI1 OLFM1 OLFM1 TGFB2 TGFB2 TGFBR3 TGFBR3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NOTCH1Notch receptor 1. (2556 aa)
TBX3T-box transcription factor 3. (743 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
MSX1Msh homeobox 1. (303 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
SNAI2Uncharacterized protein. (268 aa)
ENGEndoglin. (555 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
RTN4Reticulon. (1193 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
ADAM15ADAM metallopeptidase domain 15. (863 aa)
BMP2Bone morphogenetic protein 2. (544 aa)
HAS2Hyaluronan synthase 2. (552 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
TMEM100Uncharacterized protein. (134 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
OLFM1Olfactomedin 1. (467 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
TGFBR3Transforming growth factor beta receptor 3. (851 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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