STRINGSTRING
ENSMFAP00000024251 ENSMFAP00000024251 TGFB1 TGFB1 FGFR2 FGFR2 AXIN2 AXIN2 CITED2 CITED2 MMP14 MMP14 FOXN3 FOXN3 IHH IHH SCX SCX EXT1 EXT1 ATG9B ATG9B SMPD3 SMPD3 ATF2 ATF2 ALPL ALPL BMP6 BMP6 BMP4 BMP4 PAPPA2 PAPPA2 ENSMFAP00000008086 ENSMFAP00000008086 TRIP11 TRIP11 NAB1 NAB1 MMP13 MMP13 ENSMFAP00000009256 ENSMFAP00000009256 SP5 SP5 ENSMFAP00000009633 ENSMFAP00000009633 NEUROG1 NEUROG1 RARG RARG GLG1 GLG1 TSKU TSKU TGFB3 TGFB3 CDX1 CDX1 SHOX2 SHOX2 TBXT TBXT OSR2 OSR2 MEF2D MEF2D GLI3 GLI3 COL2A1 COL2A1 MATN1 MATN1 TRPV4 TRPV4 RARA RARA DSPP DSPP SKI SKI BMPR2 BMPR2 RAB23 RAB23 FGFR3 FGFR3 HAS2 HAS2 TMEM107 TMEM107 FOXC1 FOXC1 DLX5 DLX5 EXT2 EXT2 SERPINH1 SERPINH1 MEGF8 MEGF8 ACTN3 ACTN3 DHRS3 DHRS3 ZMPSTE24 ZMPSTE24 PAX1 PAX1 HOXA11 HOXA11 IFITM5 IFITM5 MEF2C MEF2C IFT80 IFT80 ACP5 ACP5 FGF4 FGF4 PHOSPHO1 PHOSPHO1 PEX7 PEX7 ENSMFAP00000031793 ENSMFAP00000031793 BMPR1B BMPR1B ATG9A ATG9A ANXA6 ANXA6 FREM1 FREM1 LTBP3 LTBP3 COL3A1 COL3A1 TGFBR2 TGFBR2 COMP COMP COL27A1 COL27A1 COL1A1 COL1A1 RUNX2 RUNX2 IMPAD1 IMPAD1 SCUBE2 SCUBE2 CER1 CER1 INPPL1 INPPL1 LTF LTF INSIG1 INSIG1 FGF18 FGF18 THBS3 THBS3 ENSMFAP00000038959 ENSMFAP00000038959 ENSMFAP00000039726 ENSMFAP00000039726 RARB RARB NPPC NPPC DCANP1 DCANP1 RIPPLY2 RIPPLY2 CHSY1 CHSY1 TFAP2A TFAP2A CYP26B1 CYP26B1 SFRP4 SFRP4 MMP16 MMP16 NAB2 NAB2 MSX1 MSX1 SOX9 SOX9 STC1 STC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMFAP00000024251Homeobox domain-containing protein. (143 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
FGFR2Fibroblast growth factor receptor. (810 aa)
AXIN2Axin 2. (844 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
FOXN3Forkhead box N3. (493 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
SCXScleraxis bHLH transcription factor. (145 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (922 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ALPLAlkaline phosphatase. (524 aa)
BMP6Bone morphogenetic protein 6. (509 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
PAPPA2Pappalysin 2. (1790 aa)
ENSMFAP00000008086Uncharacterized protein. (466 aa)
TRIP11Thyroid hormone receptor interactor 11. (1981 aa)
NAB1NGFI-A binding protein 1. (487 aa)
MMP13Matrix metallopeptidase 13. (489 aa)
ENSMFAP00000009256SERPIN domain-containing protein; Belongs to the serpin family. (390 aa)
SP5Sp5 transcription factor. (398 aa)
ENSMFAP00000009633Uncharacterized protein. (245 aa)
NEUROG1Neurogenin 1. (237 aa)
RARGRetinoic acid receptor gamma. (454 aa)
GLG1Golgi glycoprotein 1. (1203 aa)
TSKUTsukushi, small leucine rich proteoglycan. (353 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
CDX1Caudal type homeobox 1. (265 aa)
SHOX2Short stature homeobox 2. (355 aa)
TBXTT-box transcription factor T. (435 aa)
OSR2Odd-skipped related transciption factor 2. (402 aa)
MEF2DMyocyte enhancer factor 2D. (521 aa)
GLI3GLI family zinc finger 3. (1579 aa)
COL2A1Collagen type II alpha 1 chain. (1502 aa)
MATN1Matrilin 1. (495 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (823 aa)
RARARetinoic acid receptor alpha. (462 aa)
DSPPDentin sialophosphoprotein. (1216 aa)
SKISKI proto-oncogene. (681 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
FGFR3Fibroblast growth factor receptor. (808 aa)
HAS2Hyaluronan synthase 2. (552 aa)
TMEM107Transmembrane protein 107. (146 aa)
FOXC1Forkhead box C1. (504 aa)
DLX5Distal-less homeobox 5. (289 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (751 aa)
SERPINH1Serpin family H member 1; Belongs to the serpin family. (418 aa)
MEGF8Multiple EGF like domains 8. (2840 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (942 aa)
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (490 aa)
PAX1Paired box 1. (535 aa)
HOXA11Homeobox A11. (311 aa)
IFITM5Interferon induced transmembrane protein 5. (132 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
IFT80Intraflagellar transport 80. (777 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (325 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (267 aa)
PEX7Peroxisomal biogenesis factor 7. (323 aa)
ENSMFAP00000031793Uncharacterized protein. (412 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (851 aa)
ANXA6Annexin. (680 aa)
FREM1FRAS1 related extracellular matrix 1. (2178 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1298 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
COMPCartilage oligomeric matrix protein. (757 aa)
COL27A1Collagen type XXVII alpha 1 chain. (1853 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
RUNX2RUNX family transcription factor 2. (627 aa)
IMPAD1Inositol monophosphatase domain containing 1. (313 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (961 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1264 aa)
LTFLactotransferrin; Belongs to the transferrin family. (710 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
THBS3Thrombospondin 3. (956 aa)
ENSMFAP00000038959Uncharacterized protein. (661 aa)
ENSMFAP00000039726Fork-head domain-containing protein. (457 aa)
RARBRetinoic acid receptor beta. (448 aa)
NPPCNatriuretic peptide C. (126 aa)
DCANP1Dendritic cell associated nuclear protein. (197 aa)
RIPPLY2Ripply transcriptional repressor 2. (128 aa)
CHSY1Hexosyltransferase. (790 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
SFRP4Secreted frizzled related protein 4. (368 aa)
MMP16Matrix metallopeptidase 16. (607 aa)
NAB2NGFI-A binding protein 2. (525 aa)
MSX1Msh homeobox 1. (303 aa)
SOX9SRY-box transcription factor 9. (509 aa)
STC1Stanniocalcin 1. (247 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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