STRINGSTRING
SIRT6 SIRT6 CENPV CENPV ENSMFAP00000045161 ENSMFAP00000045161 MIS18A MIS18A SOX9 SOX9 CENPE CENPE SSRP1 SSRP1 ENSMFAP00000043336 ENSMFAP00000043336 KAT6A KAT6A H2BC15 H2BC15 ITGB3BP ITGB3BP SART3 SART3 HP1BP3 HP1BP3 SHPRH SHPRH UBTF UBTF H2BW2 H2BW2 BDP1 BDP1 TAF1B TAF1B TAF12 TAF12 TAF3 TAF3 TAF7L TAF7L CDC45 CDC45 MED28 MED28 CENPA CENPA DAXX DAXX CENPF CENPF NAA60 NAA60 ENSMFAP00000037920 ENSMFAP00000037920 ENSMFAP00000037597 ENSMFAP00000037597 MED18 MED18 GTF2A2 GTF2A2 MED26 MED26 MED25 MED25 ENSMFAP00000036233 ENSMFAP00000036233 TSPYL2 TSPYL2 MED19 MED19 TAF2 TAF2 ENSMFAP00000034233 ENSMFAP00000034233 H2BC18 H2BC18 MED8 MED8 MED27 MED27 TAF1C TAF1C CENPH CENPH MACROH2A1 MACROH2A1 ENSMFAP00000032598 ENSMFAP00000032598 CENPI CENPI CENPX CENPX GTF2H5 GTF2H5 TCF4 TCF4 LOC102120426 LOC102120426 MED24 MED24 MED4 MED4 LOC102133669 LOC102133669 LOC101866545 LOC101866545 DR1 DR1 MED22 MED22 ENSMFAP00000030798 ENSMFAP00000030798 DNAJC9 DNAJC9 OIP5 OIP5 MED21 MED21 ENSMFAP00000028463 ENSMFAP00000028463 KNTC1 KNTC1 POLR1E POLR1E DMC1 DMC1 ENSMFAP00000027305 ENSMFAP00000027305 MED11 MED11 BRF2 BRF2 RAD51 RAD51 ASF1B ASF1B MED29 MED29 HELLS HELLS ENSMFAP00000025493 ENSMFAP00000025493 ENSMFAP00000025396 ENSMFAP00000025396 SPTY2D1 SPTY2D1 POGZ POGZ CDT1 CDT1 SMARCA5 SMARCA5 ENSMFAP00000023932 ENSMFAP00000023932 SMARCA4 SMARCA4 BAZ1A BAZ1A NASP NASP ENSMFAP00000022646 ENSMFAP00000022646 TAF6 TAF6 DLGAP5 DLGAP5 MACROH2A2 MACROH2A2 ENSMFAP00000022059 ENSMFAP00000022059 CHAF1A CHAF1A TAF11 TAF11 ASF1A ASF1A SUPT16H SUPT16H ENSMFAP00000020929 ENSMFAP00000020929 ENSMFAP00000020733 ENSMFAP00000020733 ANP32B ANP32B ENSMFAP00000019423 ENSMFAP00000019423 KAT6B KAT6B NAP1L5 NAP1L5 CENPN CENPN ATRX ATRX HEY2 HEY2 MED30 MED30 GMNN GMNN CENPO CENPO TAF5 TAF5 ENSMFAP00000016028 ENSMFAP00000016028 TBP TBP ENSMFAP00000003444 ENSMFAP00000003444 MED31 MED31 CENPK CENPK BRD2 BRD2 ENSMFAP00000000767 ENSMFAP00000000767 MED15 MED15 ENSMFAP00000001669 ENSMFAP00000001669 CHAF1B CHAF1B SMYD3 SMYD3 H2BC13 H2BC13 TAF6L TAF6L PADI4 PADI4 TSPYL5 TSPYL5 ENSMFAP00000015112 ENSMFAP00000015112 ENSMFAP00000015048 ENSMFAP00000015048 H1-10 H1-10 ENSMFAP00000014826 ENSMFAP00000014826 ENSMFAP00000014776 ENSMFAP00000014776 GRWD1 GRWD1 POLE3 POLE3 BAZ2A BAZ2A G8F5U3_MACFA G8F5U3_MACFA HIST2H2BE HIST2H2BE NAP1L3 NAP1L3 H2BC3 H2BC3 H1-4 H1-4 MED7 MED7 CHRAC1 CHRAC1 G8F2Z2_MACFA G8F2Z2_MACFA H2BC5 H2BC5 ENSMFAP00000013328 ENSMFAP00000013328 ENSMFAP00000012784 ENSMFAP00000012784 MIS12 MIS12 MCM2 MCM2 ENSMFAP00000012416 ENSMFAP00000012416 H2BU1 H2BU1 H3-4 H3-4 TSPYL1 TSPYL1 H3C1 H3C1 H1-8 H1-8 CENPC CENPC H2AJ H2AJ ENSMFAP00000011563 ENSMFAP00000011563 ENSMFAP00000011394 ENSMFAP00000011394 G7P2P1_MACFA G7P2P1_MACFA H1-0 H1-0 MED23 MED23 H2AX H2AX ENSMFAP00000010617 ENSMFAP00000010617 LOC102136612 LOC102136612 H2BC1 H2BC1 H1-5 H1-5 ENSMFAP00000010040 ENSMFAP00000010040 ENSMFAP00000010034 ENSMFAP00000010034 ENSMFAP00000010006 ENSMFAP00000010006 H2BC14 H2BC14 HIST1H2BO HIST1H2BO HIST1H3B HIST1H3B GTF2B GTF2B CENPT CENPT MED14 MED14 ENSMFAP00000009378 ENSMFAP00000009378 NPM1 NPM1 HJURP HJURP RAD52 RAD52 TSPYL4 TSPYL4 BRF1 BRF1 SMARCB1 SMARCB1 TAF8 TAF8 ENSMFAP00000006991 ENSMFAP00000006991 ENSMFAP00000006813 ENSMFAP00000006813 ENSMFAP00000006551 ENSMFAP00000006551 ENSMFAP00000006511 ENSMFAP00000006511 ENSMFAP00000006505 ENSMFAP00000006505 ENSMFAP00000006058 ENSMFAP00000006058 SET SET NAP1L4 NAP1L4 TAF10 TAF10 MED16 MED16 TAF4 TAF4 MED9 MED9 RAD51C RAD51C CENPW CENPW RSF1 RSF1 PIH1D1 PIH1D1 LOC102137233 LOC102137233 TAF1 TAF1 CENPP CENPP TAF13 TAF13 NAP1L1 NAP1L1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SIRT6Sirtuin 6. (355 aa)
CENPVCentromere protein V. (219 aa)
ENSMFAP00000045161Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (191 aa)
MIS18AMIS18 kinetochore protein A. (232 aa)
SOX9SRY-box transcription factor 9. (509 aa)
CENPECentromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2701 aa)
SSRP1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa)
ENSMFAP00000043336Histone H2B; Belongs to the histone H2B family. (129 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2003 aa)
H2BC15Histone H2B; Belongs to the histone H2B family. (165 aa)
ITGB3BPIntegrin subunit beta 3 binding protein. (216 aa)
SART3Spliceosome associated factor 3, U4/U6 recycling protein. (981 aa)
HP1BP3Heterochromatin protein 1 binding protein 3. (553 aa)
SHPRHSNF2 histone linker PHD RING helicase. (1683 aa)
UBTFUpstream binding transcription factor. (764 aa)
H2BW2H2B histone family member M; Belongs to the histone H2B family. (153 aa)
BDP1B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB. (2627 aa)
TAF1BTATA box-binding protein-associated factor RNA polymerase I subunit B; Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3 (By similarity). Belongs to the RRN7/TAF1B family. (588 aa)
TAF12TATA-box binding protein associated factor 12. (213 aa)
TAF3TATA-box binding protein associated factor 3. (1008 aa)
TAF7LTATA-box binding protein associated factor 7 like. (463 aa)
CDC45Cell division cycle 45. (598 aa)
MED28Mediator complex subunit 28. (178 aa)
CENPACentromere protein A. (138 aa)
DAXXDeath domain associated protein. (740 aa)
CENPFCentromere protein F. (3113 aa)
NAA60N(alpha)-acetyltransferase 60, NatF catalytic subunit. (242 aa)
ENSMFAP00000037920CAF-1_p60_C domain-containing protein. (473 aa)
ENSMFAP00000037597Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (277 aa)
MED18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (208 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
MED26TFIIS N-terminal domain-containing protein. (600 aa)
MED25Mediator complex subunit 25. (747 aa)
ENSMFAP00000036233Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (104 aa)
TSPYL2Testis-specific Y-encoded-like protein 2; Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression (By similarity). (695 aa)
MED19Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (261 aa)
TAF2TATA-box binding protein associated factor 2. (1199 aa)
ENSMFAP00000034233TAFII28 domain-containing protein. (181 aa)
H2BC18Histone H2B; Belongs to the histone H2B family. (134 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (301 aa)
MED27Mediator complex subunit 27. (311 aa)
TAF1CTATA-box binding protein associated factor, RNA polymerase I subunit C. (843 aa)
CENPHCentromere protein H. (247 aa)
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
ENSMFAP00000032598LRRcap domain-containing protein. (217 aa)
CENPICentromere protein I. (756 aa)
CENPXCentromere protein X. (131 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
TCF4Transcription factor 4. (773 aa)
LOC102120426Uncharacterized protein. (991 aa)
MED24Uncharacterized protein. (1008 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa)
LOC102133669Histone domain-containing protein; Belongs to the histone H2B family. (175 aa)
LOC101866545Uncharacterized protein. (101 aa)
DR1Down-regulator of transcription 1. (176 aa)
MED22Mediator complex subunit 22. (200 aa)
ENSMFAP00000030798Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (253 aa)
DNAJC9DnaJ heat shock protein family (Hsp40) member C9. (259 aa)
OIP5Opa interacting protein 5. (229 aa)
MED21Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (160 aa)
ENSMFAP00000028463Uncharacterized protein. (195 aa)
KNTC1Kinetochore associated 1. (2192 aa)
POLR1ERNA polymerase I subunit E. (484 aa)
DMC1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (340 aa)
ENSMFAP00000027305Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (262 aa)
MED11Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (117 aa)
BRF2Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress; Belongs to the TFIIB family. (419 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (340 aa)
ASF1BAnti-silencing function 1B histone chaperone. (202 aa)
MED29Mediator complex subunit 29. (221 aa)
HELLSHelicase, lymphoid specific. (882 aa)
ENSMFAP00000025493Uncharacterized protein. (274 aa)
ENSMFAP00000025396Uncharacterized protein. (274 aa)
SPTY2D1SPT2 chromatin protein domain containing 1. (684 aa)
POGZPogo transposable element derived with ZNF domain. (1418 aa)
CDT1Chromatin licensing and DNA replication factor 1. (450 aa)
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1052 aa)
ENSMFAP00000023932Uncharacterized protein. (256 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
BAZ1ABromodomain adjacent to zinc finger domain 1A. (1556 aa)
NASPNuclear autoantigenic sperm protein. (779 aa)
ENSMFAP00000022646Uncharacterized protein. (264 aa)
TAF6TATA-box binding protein associated factor 6. (736 aa)
DLGAP5DLG associated protein 5. (851 aa)
MACROH2A2Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
ENSMFAP00000022059Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (189 aa)
CHAF1AChromatin assembly factor 1 subunit A. (939 aa)
TAF11TATA-box binding protein associated factor 11. (211 aa)
ASF1AAnti-silencing function 1A histone chaperone. (204 aa)
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa)
ENSMFAP00000020929Histone H2B; Belongs to the histone H2B family. (134 aa)
ENSMFAP00000020733Uncharacterized protein. (103 aa)
ANP32BAcidic nuclear phosphoprotein 32 family member B. (251 aa)
ENSMFAP00000019423Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (259 aa)
KAT6BHistone acetyltransferase KAT6B; Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2- dependent transcriptional activation. May be involved in cerebral cortex development. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity; Belongs to the MYST (SAS/MOZ) family. (2071 aa)
NAP1L5Nucleosome assembly protein 1 like 5; Belongs to the nucleosome assembly protein (NAP) family. (176 aa)
CENPNCentromere protein N. (345 aa)
ATRXATRX chromatin remodeler. (2490 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
MED30Mediator complex subunit 30. (178 aa)
GMNNGeminin DNA replication inhibitor. (209 aa)
CENPOCentromere protein O. (299 aa)
TAF5TATA-box binding protein associated factor 5. (800 aa)
ENSMFAP00000016028Uncharacterized protein. (232 aa)
TBPTATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of a BRF2-containing transcription factor complex that regulates transcription mediated by RNA polymerase III. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase [...] (326 aa)
ENSMFAP00000003444TFIIA_gamma_C domain-containing protein. (74 aa)
MED31Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa)
CENPKCentromere protein K. (269 aa)
BRD2Uncharacterized protein. (802 aa)
ENSMFAP00000000767Uncharacterized protein. (208 aa)
MED15Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (788 aa)
ENSMFAP00000001669Uncharacterized protein. (268 aa)
CHAF1BWD_REPEATS_REGION domain-containing protein. (559 aa)
SMYD3SET and MYND domain containing 3. (428 aa)
H2BC13Histone H2B; Belongs to the histone H2B family. (136 aa)
TAF6LTATA-box binding protein associated factor 6 like. (622 aa)
PADI4Peptidyl arginine deiminase 4. (663 aa)
TSPYL5TSPY like 5; Belongs to the nucleosome assembly protein (NAP) family. (286 aa)
ENSMFAP00000015112annotation not available (126 aa)
ENSMFAP00000015048annotation not available (136 aa)
H1-10H1 histone family member X. (213 aa)
ENSMFAP00000014826annotation not available (136 aa)
ENSMFAP00000014776annotation not available (136 aa)
GRWD1Glutamate rich WD repeat containing 1. (446 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
BAZ2ABromodomain adjacent to zinc finger domain 2A. (1910 aa)
G8F5U3_MACFAHistone H3; Belongs to the histone H3 family. (136 aa)
HIST2H2BEHistone H2B; Belongs to the histone H2B family. (126 aa)
NAP1L3Nucleosome assembly protein 1 like 3; Belongs to the nucleosome assembly protein (NAP) family. (509 aa)
H2BC3Histone H2B; Belongs to the histone H2B family. (126 aa)
H1-4Histone cluster 1 H1 family member e. (219 aa)
MED7Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (232 aa)
CHRAC1Chromatin accessibility complex subunit 1. (131 aa)
G8F2Z2_MACFAHistone H2B; Belongs to the histone H2B family. (126 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSMFAP00000013328Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (224 aa)
ENSMFAP00000012784annotation not available (136 aa)
MIS12Uncharacterized protein. (205 aa)
MCM2DNA helicase; Belongs to the MCM family. (900 aa)
ENSMFAP00000012416annotation not available (136 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
H3-4Histone H3; Belongs to the histone H3 family. (136 aa)
TSPYL1Uncharacterized protein. (198 aa)
H3C1H3 clustered histone 1. (136 aa)
H1-8H1 histone family member O oocyte specific. (326 aa)
CENPCCentromere protein C. (945 aa)
H2AJHistone H2A.J; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (129 aa)
ENSMFAP00000011563annotation not available (136 aa)
ENSMFAP00000011394annotation not available (126 aa)
G7P2P1_MACFAHistone H2B; Belongs to the histone H2B family. (126 aa)
H1-0H1 histone family member 0. (194 aa)
MED23Mediator complex subunit 23. (1374 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (143 aa)
ENSMFAP00000010617GFA domain-containing protein. (287 aa)
LOC102136612Histone domain-containing protein; Belongs to the histone H2B family. (175 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)
H1-5Histone cluster 1 H1 family member b. (226 aa)
ENSMFAP00000010040Histone domain-containing protein; Belongs to the histone H2B family. (67 aa)
ENSMFAP00000010034annotation not available (136 aa)
ENSMFAP00000010006annotation not available (136 aa)
H2BC14Histone H2B; Belongs to the histone H2B family. (126 aa)
HIST1H2BOHistone H2B; Belongs to the histone H2B family. (126 aa)
HIST1H3BHistone H3; Belongs to the histone H3 family. (136 aa)
GTF2BTranscription initiation factor IIB; General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA. Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II- TFIIF complex. Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle. Associates with chromatin to core promoter [...] (316 aa)
CENPTCentromere protein T; Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Part of a nucleosome-associated complex that binds specifically to histone H3- containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and [...] (561 aa)
MED14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1454 aa)
ENSMFAP00000009378Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (260 aa)
NPM1Uncharacterized protein. (305 aa)
HJURPHolliday junction recognition protein. (736 aa)
RAD52RAD52 homolog, DNA repair protein. (419 aa)
TSPYL4TSPY like 4; Belongs to the nucleosome assembly protein (NAP) family. (304 aa)
BRF1BRF1 RNA polymerase III transcription initiation factor subunit. (677 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (376 aa)
TAF8TATA-box binding protein associated factor 8. (338 aa)
ENSMFAP00000006991Histone H2B; Belongs to the histone H2B family. (149 aa)
ENSMFAP00000006813Uncharacterized protein. (245 aa)
ENSMFAP00000006551Uncharacterized protein. (229 aa)
ENSMFAP00000006511Bromo domain-containing protein. (653 aa)
ENSMFAP00000006505H15 domain-containing protein. (190 aa)
ENSMFAP00000006058Uncharacterized protein. (305 aa)
SETUncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (308 aa)
NAP1L4Nucleosome assembly protein 1 like 4; Belongs to the nucleosome assembly protein (NAP) family. (386 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (857 aa)
TAF4TATA-box binding protein associated factor 4. (635 aa)
MED9Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (146 aa)
RAD51CRAD51 paralog C. (370 aa)
CENPWCentromere protein W. (103 aa)
RSF1Remodeling and spacing factor 1. (1441 aa)
PIH1D1PIH1 domain containing 1. (290 aa)
LOC102137233Histone domain-containing protein; Belongs to the histone H2B family. (175 aa)
TAF1Transcription initiation factor TFIID subunit. (1927 aa)
CENPPCentromere protein P. (288 aa)
TAF13Transcription initiation factor TFIID subunit 13. (124 aa)
NAP1L1Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (390 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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