(50 nodes) Tertiary granule membrane network (Macaca fascicularis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	CYBA	Cytochrome b-245 alpha chain. (197 aa)
	UBR4	Ubiquitin protein ligase E3 component n-recognin 4. (5231 aa)
	CLEC5A	C-type lectin domain containing 5A. (188 aa)
	MGAM	Maltase-glucoamylase. (2745 aa)
	LAIR1	Leukocyte associated immunoglobulin like receptor 1. (287 aa)
	TRPM2	Transient receptor potential cation channel subfamily M member 2. (1511 aa)
	VAMP1	Vesicle associated membrane protein 1. (118 aa)
	CYBB	Cytochrome b-245 beta chain. (570 aa)
	ITGB2	Integrin beta. (874 aa)
	PTPRB	Protein tyrosine phosphatase receptor type B. (2215 aa)
	ATP8B4	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1191 aa)
	RAP2B	RAP2B, member of RAS oncogene family. (183 aa)
	LOC102129964	DUF1624 domain-containing protein. (518 aa)
	LAMTOR2	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa)
	GPR84	G protein-coupled receptor 84. (396 aa)
	CYSTM1	Cysteine rich transmembrane module containing 1. (97 aa)
	ITGAM	Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1147 aa)
	CLEC4C	C-type lectin domain family 4 member C. (212 aa)
	RAP2C	RAP2C, member of RAS oncogene family. (183 aa)
	ATP11A	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1192 aa)
	ITGAX	Integrin subunit alpha X; Belongs to the integrin alpha chain family. (1168 aa)
	KCNAB2	Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (415 aa)
	MCEMP1	Mast cell expressed membrane protein 1. (187 aa)
	CD177	CD177 molecule. (437 aa)
	ENSMFAP00000022629	Uncharacterized protein. (123 aa)
	ADAM8	ADAM metallopeptidase domain 8. (893 aa)
	CD93	CD93 molecule. (651 aa)
	CHRNB4	Cholinergic receptor nicotinic beta 4 subunit. (492 aa)
	ATP6V0C	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (128 aa)
	SLC11A1	Solute carrier family 11 member 1. (547 aa)
	FCAR	Fc fragment of IgA receptor. (287 aa)
	OLR1	Oxidized low density lipoprotein receptor 1. (291 aa)
	TARM1	T cell-interacting, activating receptor on myeloid cells 1. (272 aa)
	SIRPA	Uncharacterized protein. (507 aa)
	CD33	CD33 molecule. (379 aa)
	CEACAM1	Uncharacterized protein. (525 aa)
	ANO6	Anoctamin. (931 aa)
	CD53	Tetraspanin. (219 aa)
	PLD1	Phospholipase. (1074 aa)
	ADAM10	ADAM metallopeptidase domain 10. (748 aa)
	STOM	Stomatin. (288 aa)
	HGSNAT	Uncharacterized protein. (112 aa)
	VAMP8	Vesicle associated membrane protein 8. (100 aa)
	CLEC4D	C-type lectin domain family 4 member D. (215 aa)
	CLEC12A	C-type lectin domain family 12 member A. (275 aa)
	SNAP23	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
	FRMPD3	FERM and PDZ domain containing 3. (1810 aa)
	TSPAN14	Tetraspanin. (270 aa)
	SIGLEC14	Uncharacterized protein. (601 aa)
	NBEAL2	Neurobeachin like 2. (2752 aa)

Your Current Organism:

Macaca fascicularis

NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM10	TSPAN14	ENSMFAP00000034841	ENSMFAP00000044778	ADAM metallopeptidase domain 10.	Tetraspanin.	0.656
ATP11A	ATP8B4	ENSMFAP00000018500	ENSMFAP00000009828	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.424
ATP6V0C	LAMTOR2	ENSMFAP00000025207	ENSMFAP00000011775	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.	0.765
ATP8B4	ATP11A	ENSMFAP00000009828	ENSMFAP00000018500	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.424
ATP8B4	CD93	ENSMFAP00000009828	ENSMFAP00000024067	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	CD93 molecule.	0.452
CD177	CEACAM1	ENSMFAP00000022536	ENSMFAP00000031962	CD177 molecule.	Uncharacterized protein.	0.421
CD177	ITGAM	ENSMFAP00000022536	ENSMFAP00000015971	CD177 molecule.	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	0.400
CD33	CLEC12A	ENSMFAP00000031359	ENSMFAP00000042013	CD33 molecule.	C-type lectin domain family 12 member A.	0.568
CD33	ITGAM	ENSMFAP00000031359	ENSMFAP00000015971	CD33 molecule.	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	0.481
CD53	ITGAM	ENSMFAP00000032730	ENSMFAP00000015971	Tetraspanin.	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	0.420
CD53	ITGAX	ENSMFAP00000032730	ENSMFAP00000019285	Tetraspanin.	Integrin subunit alpha X; Belongs to the integrin alpha chain family.	0.417
CD53	ITGB2	ENSMFAP00000032730	ENSMFAP00000006908	Tetraspanin.	Integrin beta.	0.623
CD93	ATP8B4	ENSMFAP00000024067	ENSMFAP00000009828	CD93 molecule.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.452
CEACAM1	CD177	ENSMFAP00000031962	ENSMFAP00000022536	Uncharacterized protein.	CD177 molecule.	0.421
CEACAM1	ITGAM	ENSMFAP00000031962	ENSMFAP00000015971	Uncharacterized protein.	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	0.456
CLEC12A	CD33	ENSMFAP00000042013	ENSMFAP00000031359	C-type lectin domain family 12 member A.	CD33 molecule.	0.568
CLEC4C	ITGAX	ENSMFAP00000016876	ENSMFAP00000019285	C-type lectin domain family 4 member C.	Integrin subunit alpha X; Belongs to the integrin alpha chain family.	0.519
CYBA	CYBB	ENSMFAP00000018561	ENSMFAP00000006893	Cytochrome b-245 alpha chain.	Cytochrome b-245 beta chain.	0.997
CYBB	CYBA	ENSMFAP00000006893	ENSMFAP00000018561	Cytochrome b-245 beta chain.	Cytochrome b-245 alpha chain.	0.997
CYBB	ITGAM	ENSMFAP00000006893	ENSMFAP00000015971	Cytochrome b-245 beta chain.	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	0.551

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