STRINGSTRING
SF3B4 SF3B4 SNRPD2 SNRPD2 PRPF6 PRPF6 SNRPD3 SNRPD3 ENSMFAP00000004173 ENSMFAP00000004173 SART1 SART1 SF3A2 SF3A2 ENSMFAP00000006286 ENSMFAP00000006286 ZMAT2 ZMAT2 RBMX2 RBMX2 TXNL4A TXNL4A ENSMFAP00000008116 ENSMFAP00000008116 ENSMFAP00000008638 ENSMFAP00000008638 PRPF31 PRPF31 LSM2 LSM2 PRPF38B PRPF38B SNRPD2-2 SNRPD2-2 LSM8-2 LSM8-2 ENSMFAP00000011196 ENSMFAP00000011196 RNF113A RNF113A SNRPD2-3 SNRPD2-3 SNRPA1 SNRPA1 ENSMFAP00000012431 ENSMFAP00000012431 CWC27 CWC27 SNRPG-2 SNRPG-2 SF3B5 SF3B5 LSM5-2 LSM5-2 SNU13 SNU13 ENSMFAP00000015825 ENSMFAP00000015825 ENSMFAP00000015969 ENSMFAP00000015969 LSM4 LSM4 SNRPB2 SNRPB2 MFAP1 MFAP1 ENSMFAP00000040857 ENSMFAP00000040857 SNRPG SNRPG ENSMFAP00000040063 ENSMFAP00000040063 SNRPB SNRPB SNRPD1 SNRPD1 SF3B3 SF3B3 SNIP1 SNIP1 LSM7 LSM7 ENSMFAP00000026069 ENSMFAP00000026069 ENSMFAP00000024185 ENSMFAP00000024185 SF3A3 SF3A3 BUD13 BUD13 LSM8 LSM8 ENSMFAP00000021521 ENSMFAP00000021521 SNRPF SNRPF LSM6 LSM6 SNRPD2-4 SNRPD2-4 SF3A1 SF3A1 LSM5 LSM5 WBP4 WBP4 DHX16 DHX16 SF3B2 SF3B2 C19orf54 C19orf54 PRPF8 PRPF8 LSM3 LSM3 PHF5A PHF5A ENSMFAP00000033042 ENSMFAP00000033042 SMU1 SMU1 ENSMFAP00000031236 ENSMFAP00000031236 SF3B1 SF3B1 SF3B6 SF3B6 EFTUD2 EFTUD2 PRPF38A PRPF38A SNRNP200 SNRNP200 ENSMFAP00000044359 ENSMFAP00000044359 CWC22 CWC22 PRPF4 PRPF4 PRPF3 PRPF3 SNRPE SNRPE IK IK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SF3B4Splicing factor 3b subunit 4. (424 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
PRPF6Pre-mRNA processing factor 6. (941 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
ENSMFAP00000004173Sm domain-containing protein. (57 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa)
SF3A2Splicing factor 3a subunit 2. (464 aa)
ENSMFAP00000006286Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (81 aa)
ZMAT2Zinc finger matrin-type 2. (199 aa)
RBMX2RNA binding motif protein X-linked 2. (322 aa)
TXNL4AThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
ENSMFAP00000008116Uncharacterized protein. (352 aa)
ENSMFAP00000008638Sm domain-containing protein. (65 aa)
PRPF31Pre-mRNA processing factor 31. (499 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
PRPF38BPre-mRNA processing factor 38B. (546 aa)
SNRPD2-2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
LSM8-2U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
ENSMFAP00000011196Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
RNF113ARing finger protein 113A. (344 aa)
SNRPD2-3Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
SNRPA1U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing as component of the spliceosome. Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA. (255 aa)
ENSMFAP00000012431RRM domain-containing protein. (296 aa)
CWC27Spliceosome-associated protein CWC27 homolog; As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity. (473 aa)
SNRPG-2Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
LSM5-2U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
SNU13NHP2-like protein 1, N-terminally processed; Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. The protein undergoes a conformational change upon RNA-binding. (158 aa)
ENSMFAP00000015825Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (85 aa)
ENSMFAP00000015969Sm domain-containing protein. (59 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (139 aa)
SNRPB2Small nuclear ribonucleoprotein polypeptide B2. (225 aa)
MFAP1Testis cDNA, clone: QtsA-15815, similar to human microfibrillar-associated protein 1 (MFAP1). (439 aa)
ENSMFAP00000040857Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (53 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (96 aa)
ENSMFAP00000040063Uncharacterized protein. (51 aa)
SNRPBSmall nuclear ribonucleoprotein polypeptides B and B1. (330 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
SF3B3Splicing factor 3b subunit 3. (1217 aa)
SNIP1Smad nuclear interacting protein 1. (396 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (103 aa)
ENSMFAP00000026069SEC63 domain-containing protein. (319 aa)
ENSMFAP00000024185Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (67 aa)
SF3A3Matrin-type domain-containing protein. (504 aa)
BUD13BUD13 homolog. (619 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
ENSMFAP00000021521Uncharacterized protein. (154 aa)
SNRPFSm domain-containing protein. (127 aa)
LSM6LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
SNRPD2-4Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (85 aa)
SF3A1Splicing factor 3a subunit 1. (793 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
WBP4WW domain binding protein 4. (375 aa)
DHX16DEAH-box helicase 16. (1044 aa)
SF3B2Splicing factor 3b subunit 2. (896 aa)
C19orf54Chromosome 19 open reading frame 54. (351 aa)
PRPF8Pre-mRNA processing factor 8. (2339 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
PHF5APHD finger protein 5A. (110 aa)
ENSMFAP00000033042Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (85 aa)
SMU1SMU1 DNA replication regulator and spliceosomal factor. (513 aa)
ENSMFAP00000031236Uncharacterized protein. (424 aa)
SF3B1Uncharacterized protein. (74 aa)
SF3B6Splicing factor 3b subunit 6. (125 aa)
EFTUD2Elongation factor Tu GTP binding domain containing 2. (972 aa)
PRPF38APre-mRNA-splicing factor 38A; Involved in pre-mRNA splicing as a component of the spliceosome. (312 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2136 aa)
ENSMFAP00000044359RRM domain-containing protein. (119 aa)
CWC22CWC22 spliceosome associated protein homolog. (900 aa)
PRPF4Pre-mRNA processing factor 4. (543 aa)
PRPF3Pre-mRNA processing factor 3. (683 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
IKIK cytokine, down-regulator of HLA II. (557 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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