STRINGSTRING
STAT6 STAT6 ALAD ALAD ENSMFAP00000043889 ENSMFAP00000043889 ENSMFAP00000043205 ENSMFAP00000043205 HSPA5 HSPA5 FASN FASN JAK3 JAK3 LEF1 LEF1 GATA3 GATA3 DCSTAMP DCSTAMP ARG1 ARG1 TCF7 TCF7 IMPDH2 IMPDH2 KEAP1 KEAP1 RPLP0 RPLP0 CDK4 CDK4 IL2RG IL2RG CLEC17A CLEC17A ENSMFAP00000023113 ENSMFAP00000023113 ENSMFAP00000020439 ENSMFAP00000020439 RUFY4 RUFY4 SHPK SHPK CORO1A CORO1A MCM2 MCM2 IL24 IL24 ENSMFAP00000008754 ENSMFAP00000008754 PML PML ENSMFAP00000004931 ENSMFAP00000004931 ENSMFAP00000004476 ENSMFAP00000004476 XBP1 XBP1 ADAMTS13 ADAMTS13 MRC1 MRC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STAT6Signal transducer and activator of transcription. (847 aa)
ALADDelta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. (339 aa)
ENSMFAP00000043889Uncharacterized protein; Belongs to the heat shock protein 70 family. (619 aa)
ENSMFAP00000043205RL10P_insert domain-containing protein. (146 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
FASNFatty acid synthase. (2502 aa)
JAK3Tyrosine-protein kinase. (1124 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
GATA3GATA binding protein 3. (444 aa)
DCSTAMPDendrocyte expressed seven transmembrane protein. (470 aa)
ARG1Arginase. (322 aa)
TCF7Transcription factor 7. (398 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa)
KEAP1Kelch like ECH associated protein 1. (442 aa)
RPLP0RL10P_insert domain-containing protein. (329 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
IL2RGFibronectin type-III domain-containing protein. (369 aa)
CLEC17AC-type lectin domain containing 17A. (297 aa)
ENSMFAP00000023113RL10P_insert domain-containing protein. (290 aa)
ENSMFAP00000020439RL10P_insert domain-containing protein. (234 aa)
RUFY4RUN and FYVE domain containing 4. (584 aa)
SHPKFGGY_N domain-containing protein. (479 aa)
CORO1ACoronin-1A; May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. (461 aa)
MCM2DNA helicase; Belongs to the MCM family. (900 aa)
IL24Interleukin 24. (207 aa)
ENSMFAP00000008754RL10P_insert domain-containing protein. (173 aa)
PMLPromyelocytic leukemia. (882 aa)
ENSMFAP0000000493160S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (304 aa)
ENSMFAP00000004476RL10P_insert domain-containing protein. (270 aa)
XBP1BZIP domain-containing protein. (380 aa)
ADAMTS13ADAM metallopeptidase with thrombospondin type 1 motif 13. (1431 aa)
MRC1Mannose receptor C-type 1. (1456 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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