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| | MED31 | Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa) |
| | CENPK | Centromere protein K. (269 aa) |
| | BRD2 | Uncharacterized protein. (802 aa) |
| | SYCP3 | Synaptonemal complex protein 3; Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for centromere pairing during meiosis in male germ cells. Required for normal meiosis during spermatogenesis and male fertility. Plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2. (236 aa) |
| | VPS72 | Vacuolar protein sorting 72 homolog. (364 aa) |
| | ENSMFAP00000000767 | Uncharacterized protein. (208 aa) |
| | MED15 | Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (788 aa) |
| | ENSMFAP00000001669 | Uncharacterized protein. (268 aa) |
| | SUPT6H | Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1732 aa) |
| | CHAF1B | WD_REPEATS_REGION domain-containing protein. (559 aa) |
| | SMYD3 | SET and MYND domain containing 3. (428 aa) |
| | H2BC13 | Histone H2B; Belongs to the histone H2B family. (136 aa) |
| | ZNHIT1 | Zinc finger HIT-type containing 1. (154 aa) |
| | ACTR6 | Actin related protein 6; Belongs to the actin family. (396 aa) |
| | ENSMFAP00000003444 | TFIIA_gamma_C domain-containing protein. (74 aa) |
| | SIRT6 | Sirtuin 6. (355 aa) |
| | SETD2 | SET domain containing 2, histone lysine methyltransferase. (2544 aa) |
| | NAP1L1 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (390 aa) |
| | TAF13 | Transcription initiation factor TFIID subunit 13. (124 aa) |
| | CENPP | Centromere protein P. (288 aa) |
| | TAF1 | Transcription initiation factor TFIID subunit. (1927 aa) |
| | LOC102137233 | Histone domain-containing protein; Belongs to the histone H2B family. (175 aa) |
| | C17orf64 | Chromosome 17 open reading frame 64. (236 aa) |
| | PIH1D1 | PIH1 domain containing 1. (290 aa) |
| | RSF1 | Remodeling and spacing factor 1. (1441 aa) |
| | CENPW | Centromere protein W. (103 aa) |
| | RAD51C | RAD51 paralog C. (370 aa) |
| | MED9 | Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (146 aa) |
| | TAF4 | TATA-box binding protein associated factor 4. (635 aa) |
| | MED16 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (857 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa) |
| | NAP1L4 | Nucleosome assembly protein 1 like 4; Belongs to the nucleosome assembly protein (NAP) family. (386 aa) |
| | SET | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (308 aa) |
| | ENSMFAP00000006058 | Uncharacterized protein. (305 aa) |
| | ENSMFAP00000006505 | H15 domain-containing protein. (190 aa) |
| | ENSMFAP00000006511 | Bromo domain-containing protein. (653 aa) |
| | ENSMFAP00000006551 | Uncharacterized protein. (229 aa) |
| | ENSMFAP00000006813 | Uncharacterized protein. (245 aa) |
| | HMGA1 | Uncharacterized protein. (201 aa) |
| | ENSMFAP00000006991 | Histone H2B; Belongs to the histone H2B family. (149 aa) |
| | TAF8 | TATA-box binding protein associated factor 8. (338 aa) |
| | SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (376 aa) |
| | BRF1 | BRF1 RNA polymerase III transcription initiation factor subunit. (677 aa) |
| | TSPYL4 | TSPY like 4; Belongs to the nucleosome assembly protein (NAP) family. (304 aa) |
| | RAD52 | RAD52 homolog, DNA repair protein. (419 aa) |
| | HJURP | Holliday junction recognition protein. (736 aa) |
| | NPM1 | Uncharacterized protein. (305 aa) |
| | ENSMFAP00000009378 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (260 aa) |
| | ANP32E | Uncharacterized protein. (249 aa) |
| | MED14 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1454 aa) |
| | CENPT | Centromere protein T; Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Part of a nucleosome-associated complex that binds specifically to histone H3- containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and [...] (561 aa) |
| | GTF2B | Transcription initiation factor IIB; General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA. Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II- TFIIF complex. Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle. Associates with chromatin to core promoter [...] (316 aa) |
| | HIST1H3B | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | HIST1H2BO | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | H2BC14 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | ENSMFAP00000010006 | annotation not available (136 aa) |
| | ENSMFAP00000010034 | annotation not available (136 aa) |
| | ENSMFAP00000010040 | Histone domain-containing protein; Belongs to the histone H2B family. (67 aa) |
| | H1-5 | Histone cluster 1 H1 family member b. (226 aa) |
| | H2BC1 | Histone H2B; Belongs to the histone H2B family. (127 aa) |
| | LOC102136612 | Histone domain-containing protein; Belongs to the histone H2B family. (175 aa) |
| | ENSMFAP00000010617 | GFA domain-containing protein. (287 aa) |
| | H2AX | Histone H2A; Belongs to the histone H2A family. (143 aa) |
| | MED23 | Mediator complex subunit 23. (1374 aa) |
| | H1-0 | H1 histone family member 0. (194 aa) |
| | G7P2P1_MACFA | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | ENSMFAP00000011394 | annotation not available (126 aa) |
| | ENSMFAP00000011563 | annotation not available (136 aa) |
| | H2AJ | Histone H2A.J; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (129 aa) |
| | CENPC | Centromere protein C. (945 aa) |
| | H1-8 | H1 histone family member O oocyte specific. (326 aa) |
| | H3C1 | H3 clustered histone 1. (136 aa) |
| | TSPYL1 | Uncharacterized protein. (198 aa) |
| | H3-4 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | H2AW | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | H2BU1 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | ENSMFAP00000012317 | Uncharacterized protein. (59 aa) |
| | ENSMFAP00000012416 | annotation not available (136 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (900 aa) |
| | MIS12 | Uncharacterized protein. (205 aa) |
| | ENSMFAP00000012784 | annotation not available (136 aa) |
| | ENSMFAP00000013328 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (224 aa) |
| | H2BC5 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | G8F2Z2_MACFA | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | ENSMFAP00000013555 | Uncharacterized protein. (86 aa) |
| | CHRAC1 | Chromatin accessibility complex subunit 1. (131 aa) |
| | MED7 | Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (232 aa) |
| | FSHR | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa) |
| | H1-4 | Histone cluster 1 H1 family member e. (219 aa) |
| | H2BC3 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | NAP1L3 | Nucleosome assembly protein 1 like 3; Belongs to the nucleosome assembly protein (NAP) family. (509 aa) |
| | HIST2H2BE | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | G8F5U3_MACFA | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | BAZ2A | Bromodomain adjacent to zinc finger domain 2A. (1910 aa) |
| | POLE3 | DNA polymerase epsilon 3, accessory subunit. (147 aa) |
| | GRWD1 | Glutamate rich WD repeat containing 1. (446 aa) |
| | ENSMFAP00000014776 | annotation not available (136 aa) |
| | DMAP1 | DNA methyltransferase 1 associated protein 1. (612 aa) |
| | ENSMFAP00000014826 | annotation not available (136 aa) |
| | H1-10 | H1 histone family member X. (213 aa) |
| | ENSMFAP00000015048 | annotation not available (136 aa) |
| | ENSMFAP00000015112 | annotation not available (126 aa) |
| | TSPYL5 | TSPY like 5; Belongs to the nucleosome assembly protein (NAP) family. (286 aa) |
| | PADI4 | Peptidyl arginine deiminase 4. (663 aa) |
| | TAF6L | TATA-box binding protein associated factor 6 like. (622 aa) |
| | LIN54 | Lin-54 DREAM MuvB core complex component. (749 aa) |
| | SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1270 aa) |
| | TBP | TATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of a BRF2-containing transcription factor complex that regulates transcription mediated by RNA polymerase III. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase [...] (326 aa) |
| | ENSMFAP00000016028 | Uncharacterized protein. (232 aa) |
| | CHD1 | Chromodomain helicase DNA binding protein 1. (1712 aa) |
| | TAF5 | TATA-box binding protein associated factor 5. (800 aa) |
| | CENPO | Centromere protein O. (299 aa) |
| | GMNN | Geminin DNA replication inhibitor. (209 aa) |
| | MED30 | Mediator complex subunit 30. (178 aa) |
| | HEY2 | Hes related family bHLH transcription factor with YRPW motif 2. (337 aa) |
| | ATRX | ATRX chromatin remodeler. (2490 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (473 aa) |
| | SMARCD3 | SWIB domain-containing protein. (483 aa) |
| | CENPN | Centromere protein N. (345 aa) |
| | NAP1L5 | Nucleosome assembly protein 1 like 5; Belongs to the nucleosome assembly protein (NAP) family. (176 aa) |
| | KAT6B | Histone acetyltransferase KAT6B; Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2- dependent transcriptional activation. May be involved in cerebral cortex development. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity; Belongs to the MYST (SAS/MOZ) family. (2071 aa) |
| | ARID1A | AT-rich interaction domain 1A. (2268 aa) |
| | ENSMFAP00000019423 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (259 aa) |
| | ANP32B | Acidic nuclear phosphoprotein 32 family member B. (251 aa) |
| | SRCAP | Uncharacterized protein. (3229 aa) |
| | ENSMFAP00000020733 | Uncharacterized protein. (103 aa) |
| | ENSMFAP00000020929 | Histone H2B; Belongs to the histone H2B family. (134 aa) |
| | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa) |
| | ASF1A | Anti-silencing function 1A histone chaperone. (204 aa) |
| | TAF11 | TATA-box binding protein associated factor 11. (211 aa) |
| | CHD2 | Uncharacterized protein. (1834 aa) |
| | CHAF1A | Chromatin assembly factor 1 subunit A. (939 aa) |
| | ENSMFAP00000022059 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (189 aa) |
| | MACROH2A2 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa) |
| | DLGAP5 | DLG associated protein 5. (851 aa) |
| | TAF6 | TATA-box binding protein associated factor 6. (736 aa) |
| | ENSMFAP00000022646 | Uncharacterized protein. (264 aa) |
| | SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1077 aa) |
| | NASP | Nuclear autoantigenic sperm protein. (779 aa) |
| | BAZ1A | Bromodomain adjacent to zinc finger domain 1A. (1556 aa) |
| | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa) |
| | ENSMFAP00000023932 | Uncharacterized protein. (256 aa) |
| | SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1052 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (450 aa) |
| | POGZ | Pogo transposable element derived with ZNF domain. (1418 aa) |
| | SPTY2D1 | SPT2 chromatin protein domain containing 1. (684 aa) |
| | ENSMFAP00000025396 | Uncharacterized protein. (274 aa) |
| | NFE2 | Nuclear factor, erythroid 2. (373 aa) |
| | ENSMFAP00000025493 | Uncharacterized protein. (274 aa) |
| | HELLS | Helicase, lymphoid specific. (882 aa) |
| | MED29 | Mediator complex subunit 29. (221 aa) |
| | ASF1B | Anti-silencing function 1B histone chaperone. (202 aa) |
| | RAD51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (340 aa) |
| | ENSMFAP00000026582 | HMG box domain-containing protein. (177 aa) |
| | BRF2 | Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress; Belongs to the TFIIB family. (419 aa) |
| | BRDT | Bromodomain testis-specific protein; Testis-specific chromatin protein that specifically binds histone H4 acetylated at 'Lys-5' and 'Lys-8' (H4K5ac and H4K8ac, respectively) and plays a key role in spermatogenesis. Required in late pachytene spermatocytes: plays a role in meiotic and post-meiotic cells by binding to acetylated histones at the promoter of specific meiotic and post-meiotic genes, facilitating their activation at the appropriate time. In the post-meiotic phase of spermatogenesis, binds to hyperacetylated histones and participates in their general removal from DNA. Also re [...] (947 aa) |
| | MED11 | Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (117 aa) |
| | ENSMFAP00000027305 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (262 aa) |
| | DMC1 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (340 aa) |
| | POLR1E | RNA polymerase I subunit E. (484 aa) |
| | KNTC1 | Kinetochore associated 1. (2192 aa) |
| | ENSMFAP00000028463 | Uncharacterized protein. (195 aa) |
| | MED21 | Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (160 aa) |
| | OIP5 | Opa interacting protein 5. (229 aa) |
| | SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa) |
| | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9. (259 aa) |
| | ENSMFAP00000030798 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (253 aa) |
| | MED22 | Mediator complex subunit 22. (200 aa) |
| | DR1 | Down-regulator of transcription 1. (176 aa) |
| | LOC101866545 | Uncharacterized protein. (101 aa) |
| | TNP2 | Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. (141 aa) |
| | LOC102133669 | Histone domain-containing protein; Belongs to the histone H2B family. (175 aa) |
| | MED4 | Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa) |
| | MED24 | Uncharacterized protein. (1008 aa) |
| | ENSMFAP00000031470 | Uncharacterized protein. (138 aa) |
| | LOC102120426 | Uncharacterized protein. (991 aa) |
| | TCF4 | Transcription factor 4. (773 aa) |
| | GTF2H5 | General transcription factor IIH subunit 5. (71 aa) |
| | CENPX | Centromere protein X. (131 aa) |
| | CENPI | Centromere protein I. (756 aa) |
| | ENSMFAP00000032598 | LRRcap domain-containing protein. (217 aa) |
| | MACROH2A1 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa) |
| | CENPH | Centromere protein H. (247 aa) |
| | TAF1C | TATA-box binding protein associated factor, RNA polymerase I subunit C. (843 aa) |
| | MED27 | Mediator complex subunit 27. (311 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (445 aa) |
| | MED8 | Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (301 aa) |
| | H2BC18 | Histone H2B; Belongs to the histone H2B family. (134 aa) |
| | ENSMFAP00000034233 | TAFII28 domain-containing protein. (181 aa) |
| | PSME4 | Proteasome activator subunit 4. (1844 aa) |
| | TAF2 | TATA-box binding protein associated factor 2. (1199 aa) |
| | CHD5 | Chromodomain helicase DNA binding protein 5. (1983 aa) |
| | MED19 | Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (261 aa) |
| | TSPYL2 | Testis-specific Y-encoded-like protein 2; Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression (By similarity). (695 aa) |
| | ENSMFAP00000036233 | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (104 aa) |
| | MED25 | Mediator complex subunit 25. (747 aa) |
| | MED26 | TFIIS N-terminal domain-containing protein. (600 aa) |
| | GTF2A2 | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa) |
| | MED18 | Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (208 aa) |
| | ENSMFAP00000037597 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (277 aa) |
| | ENSMFAP00000037920 | CAF-1_p60_C domain-containing protein. (473 aa) |
| | SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (493 aa) |
| | NAA60 | N(alpha)-acetyltransferase 60, NatF catalytic subunit. (242 aa) |
| | CENPF | Centromere protein F. (3113 aa) |
| | ARID2 | AT-rich interaction domain 2. (1815 aa) |
| | DAXX | Death domain associated protein. (740 aa) |
| | CENPA | Centromere protein A. (138 aa) |
| | MED28 | Mediator complex subunit 28. (178 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (486 aa) |
| | CDC45 | Cell division cycle 45. (598 aa) |
| | TAF7L | TATA-box binding protein associated factor 7 like. (463 aa) |
| | YEATS4 | YEATS domain containing 4. (227 aa) |
| | MCM3AP | Minichromosome maintenance complex component 3 associated protein. (1980 aa) |
| | TAF3 | TATA-box binding protein associated factor 3. (1008 aa) |
| | TAF12 | TATA-box binding protein associated factor 12. (213 aa) |
| | TAF1B | TATA box-binding protein-associated factor RNA polymerase I subunit B; Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3 (By similarity). Belongs to the RRN7/TAF1B family. (588 aa) |
| | BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB. (2627 aa) |
| | H2BW2 | H2B histone family member M; Belongs to the histone H2B family. (153 aa) |
| | UBTF | Upstream binding transcription factor. (764 aa) |
| | SHPRH | SNF2 histone linker PHD RING helicase. (1683 aa) |
| | HP1BP3 | Heterochromatin protein 1 binding protein 3. (553 aa) |
| | SART3 | Spliceosome associated factor 3, U4/U6 recycling protein. (981 aa) |
| | ITGB3BP | Integrin subunit beta 3 binding protein. (216 aa) |
| | H2BC15 | Histone H2B; Belongs to the histone H2B family. (165 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | KAT6A | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2003 aa) |
| | ENSMFAP00000043336 | Histone H2B; Belongs to the histone H2B family. (129 aa) |
| | SSRP1 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa) |
| | CENPE | Centromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2701 aa) |
| | SOX9 | SRY-box transcription factor 9. (509 aa) |
| | MIS18A | MIS18 kinetochore protein A. (232 aa) |
| | ENSMFAP00000045161 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (191 aa) |
| | CENPV | Centromere protein V. (219 aa) |
| | SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa) |
