Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGO3 | CEBPA | ENSMFAP00000021730 | ENSMFAP00000014016 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. | CCAAT enhancer binding protein alpha. | 0.426 |
| AGO3 | DGCR8 | ENSMFAP00000021730 | ENSMFAP00000043233 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. | DGCR8 microprocessor complex subunit. | 0.620 |
| CCNE1 | TERT | ENSMFAP00000041076 | ENSMFAP00000020363 | Cyclin E1; Belongs to the cyclin family. | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] | 0.635 |
| CCNE1 | TP53 | ENSMFAP00000041076 | ENSMFAP00000038526 | Cyclin E1; Belongs to the cyclin family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.570 |
| CD109 | TGFB1 | ENSMFAP00000026384 | ENSMFAP00000000106 | CD109 molecule. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.534 |
| CDKN2C | TP53 | ENSMFAP00000012421 | ENSMFAP00000038526 | Cyclin dependent kinase inhibitor 2C. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.932 |
| CEBPA | AGO3 | ENSMFAP00000014016 | ENSMFAP00000021730 | CCAAT enhancer binding protein alpha. | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. | 0.426 |
| CEBPA | RUNX2 | ENSMFAP00000014016 | ENSMFAP00000035682 | CCAAT enhancer binding protein alpha. | RUNX family transcription factor 2. | 0.511 |
| CEBPA | TGFB1 | ENSMFAP00000014016 | ENSMFAP00000000106 | CCAAT enhancer binding protein alpha. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.404 |
| CEBPA | TP53 | ENSMFAP00000014016 | ENSMFAP00000038526 | CCAAT enhancer binding protein alpha. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.610 |
| CEBPA | WNT10B | ENSMFAP00000014016 | ENSMFAP00000024644 | CCAAT enhancer binding protein alpha. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.477 |
| CTNNB1 | FGF10 | ENSMFAP00000007553 | ENSMFAP00000034415 | Catenin beta 1. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.403 |
| CTNNB1 | FGF8 | ENSMFAP00000007553 | ENSMFAP00000034520 | Catenin beta 1. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.402 |
| CTNNB1 | HMGA2 | ENSMFAP00000007553 | ENSMFAP00000023343 | Catenin beta 1. | High mobility group AT-hook 2. | 0.415 |
| CTNNB1 | KAT7 | ENSMFAP00000007553 | ENSMFAP00000002987 | Catenin beta 1. | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | 0.447 |
| CTNNB1 | KDM1A | ENSMFAP00000007553 | ENSMFAP00000000692 | Catenin beta 1. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.439 |
| CTNNB1 | KDR | ENSMFAP00000007553 | ENSMFAP00000023055 | Catenin beta 1. | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.923 |
| CTNNB1 | NF2 | ENSMFAP00000007553 | ENSMFAP00000034609 | Catenin beta 1. | Neurofibromin 2. | 0.552 |
| CTNNB1 | NOTCH1 | ENSMFAP00000007553 | ENSMFAP00000046047 | Catenin beta 1. | Notch receptor 1. | 0.702 |
| CTNNB1 | PTPRC | ENSMFAP00000007553 | ENSMFAP00000026904 | Catenin beta 1. | Protein tyrosine phosphatase receptor type C. | 0.478 |
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