STRINGSTRING
TWSG1 TWSG1 SLC2A10 SLC2A10 CREBBP CREBBP CHST11 CHST11 HDAC2 HDAC2 TGFB1 TGFB1 BRMS1 BRMS1 HJV HJV MTMR4 MTMR4 SNW1 SNW1 PRDM16 PRDM16 ZC3H3 ZC3H3 SPRY2 SPRY2 MYOCD MYOCD XBP1 XBP1 FBXL15 FBXL15 EID2 EID2 RASL11B RASL11B LEFTY1 LEFTY1 CITED2 CITED2 BAMBI BAMBI CDKN1C CDKN1C CDH5 CDH5 HIPK2 HIPK2 PPM1A PPM1A ADAMTSL2 ADAMTSL2 LEMD2 LEMD2 SMAD3 SMAD3 CHRD CHRD OGT OGT NOTCH1 NOTCH1 PELO PELO RNF165 RNF165 BMP15 BMP15 ENSMFAP00000045669 ENSMFAP00000045669 SAP30L SAP30L ABL1 ABL1 EP300 EP300 GDF6 GDF6 DAND5 DAND5 BMPER BMPER GDF11 GDF11 CILP CILP LRP1 LRP1 LOC102144954 LOC102144954 ENSMFAP00000043889 ENSMFAP00000043889 FBN1 FBN1 MSX1 MSX1 ADAM17 ADAM17 CHRDL1 CHRDL1 GDF3 GDF3 LATS1 LATS1 ENSMFAP00000042475 ENSMFAP00000042475 DLX1 DLX1 SFRP4 SFRP4 PIN1 PIN1 ACVRL1 ACVRL1 HSPA5 HSPA5 HOXA13 HOXA13 TGFB1I1 TGFB1I1 NODAL NODAL TRIM33 TRIM33 KIAA0319 KIAA0319 ENSMFAP00000041061 ENSMFAP00000041061 ACVR2B ACVR2B NKX2-1 NKX2-1 CAV1 CAV1 TFAP2B TFAP2B SIRT1 SIRT1 DNM2 DNM2 TBX20 TBX20 BCL9L BCL9L CAV3 CAV3 BMP10 BMP10 HSP90AB1 HSP90AB1 IL17RD IL17RD ENG ENG WNT1 WNT1 FKBP8 FKBP8 FLCN FLCN NBL1 NBL1 SNX25 SNX25 CER1 CER1 SFRP2 SFRP2 CTDSPL2 CTDSPL2 TP53 TP53 DKK1 DKK1 ENSMFAP00000037907 ENSMFAP00000037907 SDCBP SDCBP INHBA INHBA SAP30 SAP30 BRMS1L BRMS1L ENSMFAP00000037561 ENSMFAP00000037561 AXIN1 AXIN1 TGFBR3 TGFBR3 TGFB2 TGFB2 PARP1 PARP1 INHA INHA BMPR1A BMPR1A SAP130 SAP130 MEN1 MEN1 GDF7 GDF7 SMURF2 SMURF2 SIN3A SIN3A CCN1 CCN1 KCP KCP FSTL3 FSTL3 HTRA3 HTRA3 BMP6 BMP6 DAB2 DAB2 BMP4 BMP4 SKOR1 SKOR1 NOTCH2 NOTCH2 ZBTB7A ZBTB7A MAGI2 MAGI2 STRAP STRAP TNFAIP6 TNFAIP6 LDLRAD4 LDLRAD4 HFE HFE VWC2L VWC2L SOSTDC1 SOSTDC1 SPRY1 SPRY1 TGFBR3L TGFBR3L MPP5 MPP5 SKOR2 SKOR2 NEO1 NEO1 LINGO3 LINGO3 SOX11 SOX11 GLG1 GLG1 NREP NREP ZNF703 ZNF703 VASN VASN TGFB3 TGFB3 C10H20orf27 C10H20orf27 UBE2O UBE2O NOG NOG CCN3 CCN3 EMILIN1 EMILIN1 SKIL SKIL ENSMFAP00000014529 ENSMFAP00000014529 FOLR1 FOLR1 WFIKKN1 WFIKKN1 GREM2 GREM2 FST FST ZEB2 ZEB2 PDPK1 PDPK1 SPRED2 SPRED2 BMP5 BMP5 RNF111 RNF111 LTBP4 LTBP4 ENSMFAP00000016148 ENSMFAP00000016148 SORL1 SORL1 SPRED3 SPRED3 ENSMFAP00000017173 ENSMFAP00000017173 PPARA PPARA RGMA RGMA SPRED1 SPRED1 ACVR1B ACVR1B GDF2 GDF2 SKI SKI BMPR2 BMPR2 KIAA1324L KIAA1324L BMP7 BMP7 ONECUT2 ONECUT2 INHBC INHBC ITGA8 ITGA8 BMP3 BMP3 ING2 ING2 PCSK6 PCSK6 THBS1 THBS1 ASPN ASPN SPART SPART GATA4 GATA4 IGSF1 IGSF1 SFRP1 SFRP1 PBLD PBLD SMURF1 SMURF1 LATS2 LATS2 TMPRSS6 TMPRSS6 INHBE INHBE SCUBE3 SCUBE3 SMAD7 SMAD7 INHBB INHBB GIPC3 GIPC3 CRIM1 CRIM1 DKK3 DKK3 KDR KDR UCMA UCMA VEPH1 VEPH1 ITGA3 ITGA3 SULF1 SULF1 CDKN2A CDKN2A LOX LOX STK11 STK11 ZNF451 ZNF451 FAM89B FAM89B ING1 ING1 BMP2 BMP2 ARID4B ARID4B ENSMFAP00000025331 ENSMFAP00000025331 LTBP1 LTBP1 TET1 TET1 HTRA1 HTRA1 CD109 CD109 GATA6 GATA6 IL17F IL17F UBL3 UBL3 ZNF423 ZNF423 SMAD6 SMAD6 TGFBR1 TGFBR1 RBPMS2 RBPMS2 LEMD3 LEMD3 DMRT1 DMRT1 PMEPA1 PMEPA1 SOST SOST LRP2 LRP2 LRG1 LRG1 WFIKKN2 WFIKKN2 LOC102134040 LOC102134040 SMAD2 SMAD2 HTRA4 HTRA4 ENSMFAP00000029266 ENSMFAP00000029266 FBN2 FBN2 CHRDL2 CHRDL2 SPINT3 SPINT3 STUB1 STUB1 CRB2 CRB2 ACVR1 ACVR1 DACT2 DACT2 CIDEA CIDEA CILP2 CILP2 GIPC1 GIPC1 NUP93 NUP93 ZEB1 ZEB1 GDF10 GDF10 GIPC2 GIPC2 FGF9 FGF9 NRROS NRROS RBPMS RBPMS NUMA1 NUMA1 SHH SHH GDF5 GDF5 SFRP5 SFRP5 SMAD4 SMAD4 ENSMFAP00000032703 ENSMFAP00000032703 ACVR2A ACVR2A FGF10 FGF10 JAK2 JAK2 TGFBR2 TGFBR2 FERMT1 FERMT1 ENSMFAP00000035525 ENSMFAP00000035525 WNT5A WNT5A VWC2 VWC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
SLC2A10Solute carrier family 2 member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (555 aa)
CREBBPCREB binding protein. (2442 aa)
CHST11Carbohydrate sulfotransferase. (352 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
BRMS1Uncharacterized protein. (262 aa)
HJVHemojuvelin BMP co-receptor. (427 aa)
MTMR4Myotubularin related protein 4. (1195 aa)
SNW1SNW domain containing 1. (571 aa)
PRDM16PR/SET domain 16. (1276 aa)
ZC3H3Zinc finger CCCH-type containing 3. (950 aa)
SPRY2Protein sprouty homolog 2; May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis. (338 aa)
MYOCDMyocardin. (964 aa)
XBP1BZIP domain-containing protein. (380 aa)
FBXL15F-box and leucine rich repeat protein 15. (300 aa)
EID2EP300 interacting inhibitor of differentiation 2. (236 aa)
RASL11BRAS like family 11 member B. (248 aa)
LEFTY1Left-right determination factor. (366 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
CDKN1CUncharacterized protein. (215 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
HIPK2Homeodomain interacting protein kinase 2. (1196 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
ADAMTSL2ADAMTS like 2. (1049 aa)
LEMD2LEM domain containing 2. (493 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
CHRDChordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (955 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
NOTCH1Notch receptor 1. (2556 aa)
PELOProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
RNF165Ring finger protein 165. (346 aa)
BMP15Bone morphogenetic protein 15. (393 aa)
ENSMFAP00000045669SKIP_SNW domain-containing protein. (467 aa)
SAP30LSAP30 like. (184 aa)
ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase. (901 aa)
EP300E1A binding protein p300. (2414 aa)
GDF6Growth differentiation factor 6. (455 aa)
DAND5DAN domain BMP antagonist family member 5. (189 aa)
BMPERBMP binding endothelial regulator. (685 aa)
GDF11Growth differentiation factor 11. (342 aa)
CILPCartilage intermediate layer protein. (1184 aa)
LRP1LDL receptor related protein 1. (4544 aa)
LOC102144954Left-right determination factor. (366 aa)
ENSMFAP00000043889Uncharacterized protein; Belongs to the heat shock protein 70 family. (619 aa)
FBN1Fibrillin 1. (2871 aa)
MSX1Msh homeobox 1. (303 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
CHRDL1Chordin like 1. (458 aa)
GDF3Growth differentiation factor 3. (364 aa)
LATS1Large tumor suppressor kinase 1. (1130 aa)
ENSMFAP00000042475Uncharacterized protein. (290 aa)
DLX1Homeobox domain-containing protein. (255 aa)
SFRP4Secreted frizzled related protein 4. (368 aa)
PIN1Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis/trans isomerase (PPIase) that binds to and isomerizes specific phosphorylated Ser/Thr-Pro (pSer/Thr-Pro) motifs. By inducing conformational changes in a subset of phosphorylated proteins, acts as a molecular switch in multiple cellular processes. Displays a preference for acidic residues located N-terminally to the proline bond to be isomerized. Regulates mitosis presumably by interacting with NIMA and attenuating its mitosis- promoting activity. Down-regulates kinase activity of BTK. Can transactivate multiple [...] (145 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
HOXA13Homeobox A13. (228 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (467 aa)
NODALNodal growth differentiation factor. (347 aa)
TRIM33Tripartite motif containing 33. (1127 aa)
KIAA0319KIAA0319. (1072 aa)
ENSMFAP00000041061TPR_REGION domain-containing protein. (134 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (518 aa)
NKX2-1NK2 homeobox 1. (448 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
TFAP2BTranscription factor AP-2 beta. (469 aa)
SIRT1Sirtuin 1. (743 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
TBX20T-box transcription factor 20. (447 aa)
BCL9LBCL9 like. (1500 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
HSP90AB1Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] (724 aa)
IL17RDInterleukin 17 receptor D. (739 aa)
ENGEndoglin. (555 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
FKBP8Peptidylprolyl isomerase. (413 aa)
FLCNFolliculin. (579 aa)
NBL1NBL1, DAN family BMP antagonist. (216 aa)
SNX25Sorting nexin 25. (879 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
CTDSPL2CTD small phosphatase like 2. (466 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (393 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
ENSMFAP00000037907Fork-head domain-containing protein. (260 aa)
SDCBPUncharacterized protein. (324 aa)
INHBAInhibin subunit beta A. (426 aa)
SAP30Sin3A associated protein 30. (220 aa)
BRMS1LBRMS1 like transcriptional repressor. (323 aa)
ENSMFAP00000037561Uncharacterized protein. (115 aa)
AXIN1Axin 1. (867 aa)
TGFBR3Transforming growth factor beta receptor 3. (851 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SAP130Sin3A associated protein 130. (1083 aa)
MEN1Menin 1. (615 aa)
GDF7Growth differentiation factor 7. (450 aa)
SMURF2E3 ubiquitin-protein ligase. (748 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
CCN1Cellular communication network factor 1. (381 aa)
KCPKielin cysteine rich BMP regulator. (1630 aa)
FSTL3Follistatin like 3. (154 aa)
HTRA3HtrA serine peptidase 3. (453 aa)
BMP6Bone morphogenetic protein 6. (509 aa)
DAB2DAB adaptor protein 2. (770 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
SKOR1SKI family transcriptional corepressor 1. (964 aa)
NOTCH2Notch receptor 2. (2610 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (584 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1283 aa)
STRAPWD_REPEATS_REGION domain-containing protein. (363 aa)
TNFAIP6TNF alpha induced protein 6. (277 aa)
LDLRAD4Uncharacterized protein. (306 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (348 aa)
VWC2LVon Willebrand factor C domain-containing protein 2-like; May play a role in neurogenesis. May play a role in bone differentiation and matrix mineralization. (222 aa)
SOSTDC1Sclerostin domain containing 1. (230 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
TGFBR3LTransforming growth factor beta receptor 3 like. (312 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
SKOR2SKI family transcriptional corepressor 2. (911 aa)
NEO1Neogenin 1. (1434 aa)
LINGO3Leucine rich repeat and Ig domain containing 3. (592 aa)
SOX11Transcription factor SOX. (441 aa)
GLG1Golgi glycoprotein 1. (1203 aa)
NREPNeuronal regeneration-related protein; May have roles in neural function and cellular differentiation. Ectopic expression promotes axonal regeneration, induces differentiation of fibroblast into myofibroblast, induces myofibroblast ameboid migration, augments motility of gliomas, and increases retinoic-acid regulation of lipid-droplet biogenesis. Down- regulates the expression of TGFB1 and TGFB2 but not of TGFB3. May play a role in the regulation of alveolar generation. (112 aa)
ZNF703Zinc finger protein 703. (591 aa)
VASNVasorin. (673 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
C10H20orf27Uncharacterized protein. (199 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1293 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
CCN3Cellular communication network factor 3. (370 aa)
EMILIN1Elastin microfibril interfacer 1. (1016 aa)
SKILSKI like proto-oncogene. (684 aa)
ENSMFAP00000014529Uncharacterized protein. (106 aa)
FOLR1Folate receptor alpha. (257 aa)
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa)
GREM2Gremlin. (168 aa)
FSTFollistatin. (344 aa)
ZEB2Zinc finger E-box binding homeobox 2. (1253 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (510 aa)
SPRED2Sprouty related EVH1 domain containing 2. (432 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
RNF111Ring finger protein 111. (1002 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1624 aa)
ENSMFAP00000016148PPM-type phosphatase domain-containing protein. (280 aa)
SORL1Sortilin related receptor 1. (2212 aa)
SPRED3Sprouty related EVH1 domain containing 3. (424 aa)
ENSMFAP00000017173PDZ domain-containing protein. (255 aa)
PPARAPeroxisome proliferator activated receptor alpha. (467 aa)
RGMARepulsive guidance molecule A; Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA- ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG- PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition. Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inacti [...] (458 aa)
SPRED1Sprouty related EVH1 domain containing 1. (444 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
GDF2Growth differentiation factor 2. (429 aa)
SKISKI proto-oncogene. (681 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
KIAA1324LKIAA1324 like. (1029 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
ONECUT2One cut domain family member. (481 aa)
INHBCInhibin subunit beta C. (352 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (474 aa)
ING2Inhibitor of growth protein. (280 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (944 aa)
THBS1Thrombospondin 1. (1173 aa)
ASPNAsporin. (333 aa)
SPARTSpartin. (666 aa)
GATA4GATA binding protein 4. (425 aa)
IGSF1Immunoglobulin superfamily member 1. (1354 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
PBLDPhenazine biosynthesis like protein domain containing. (288 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
LATS2Large tumor suppressor kinase 2. (911 aa)
TMPRSS6Transmembrane serine protease 6; Belongs to the peptidase S1 family. (821 aa)
INHBEInhibin subunit beta E. (351 aa)
SCUBE3Signal peptide, CUB domain and EGF like domain containing 3. (993 aa)
SMAD7Mothers against decapentaplegic homolog. (495 aa)
INHBBInhibin subunit beta B. (360 aa)
GIPC3GIPC PDZ domain containing family member 3. (312 aa)
CRIM1Cysteine rich transmembrane BMP regulator 1. (1040 aa)
DKK3Dickkopf_N domain-containing protein. (387 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
UCMAUpper zone of growth plate and cartilage matrix associated. (138 aa)
VEPH1Ventricular zone expressed PH domain containing 1. (833 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1064 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (869 aa)
CDKN2AANK_REP_REGION domain-containing protein. (160 aa)
LOXLysyl oxidase. (417 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
ZNF451Zinc finger protein 451. (1061 aa)
FAM89BFamily with sequence similarity 89 member B. (154 aa)
ING1Inhibitor of growth protein. (417 aa)
BMP2Bone morphogenetic protein 2. (544 aa)
ARID4BAT-rich interaction domain 4B. (1314 aa)
ENSMFAP00000025331Uncharacterized protein. (259 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1683 aa)
TET1Tet methylcytosine dioxygenase 1. (2132 aa)
HTRA1HtrA serine peptidase 1. (481 aa)
CD109CD109 molecule. (1444 aa)
GATA6GATA binding protein 6. (557 aa)
IL17FInterleukin 17F. (163 aa)
UBL3Ubiquitin-like protein. (117 aa)
ZNF423Zinc finger protein 423. (1316 aa)
SMAD6Mothers against decapentaplegic homolog. (496 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
RBPMS2RNA binding protein, mRNA processing factor 2. (209 aa)
LEMD3LEM domain containing 3. (909 aa)
DMRT1Doublesex and mab-3 related transcription factor 1. (373 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (287 aa)
SOSTSclerostin. (213 aa)
LRP2LDL receptor related protein 2. (4655 aa)
LRG1Leucine rich alpha-2-glycoprotein 1. (347 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (576 aa)
LOC102134040Uncharacterized protein. (1244 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
HTRA4HtrA serine peptidase 4. (476 aa)
ENSMFAP00000029266TGF_BETA_2 domain-containing protein. (344 aa)
FBN2Fibrillin 2. (2912 aa)
CHRDL2Chordin like 2. (452 aa)
SPINT3Serine peptidase inhibitor, Kunitz type 3. (89 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
CRB2Crumbs cell polarity complex component 2. (1350 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
DACT2Dishevelled binding antagonist of beta catenin 2. (773 aa)
CIDEACell death inducing DFFA like effector a. (219 aa)
CILP2Cartilage intermediate layer protein 2. (1156 aa)
GIPC1GIPC PDZ domain containing family member 1. (333 aa)
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (880 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1127 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (477 aa)
GIPC2GIPC PDZ domain containing family member 2. (315 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
NRROSNegative regulator of reactive oxygen species. (732 aa)
RBPMSRNA binding protein, mRNA processing factor. (219 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2133 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
GDF5Growth differentiation factor 5. (499 aa)
SFRP5Secreted frizzled related protein 5. (315 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ENSMFAP00000032703Uncharacterized protein. (103 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
JAK2Tyrosine-protein kinase. (1139 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
FERMT1Fermitin family member 1. (677 aa)
ENSMFAP00000035525TGF_BETA_2 domain-containing protein. (347 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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