STRINGSTRING
ING2 ING2 PTP4A3 PTP4A3 SMAD6 SMAD6 ZNF423 ZNF423 UBL3 UBL3 PRDM14 PRDM14 IL17F IL17F MYO1C MYO1C GATA6 GATA6 CD109 CD109 VEGFB VEGFB FGF16 FGF16 HTRA1 HTRA1 TET1 TET1 LTBP1 LTBP1 ENSMFAP00000025331 ENSMFAP00000025331 ARID4B ARID4B BMP2 BMP2 NGFR NGFR ING1 ING1 FAM89B FAM89B ZNF451 ZNF451 STK11 STK11 LOX LOX CDKN2A CDKN2A SULF1 SULF1 ADAMTS3 ADAMTS3 ITGA3 ITGA3 VEPH1 VEPH1 KDR KDR DKK3 DKK3 CRIM1 CRIM1 GIPC3 GIPC3 CASK CASK SMAD7 SMAD7 FAM20C FAM20C ADGRA2 ADGRA2 ADAMTSL2 ADAMTSL2 LEMD2 LEMD2 SMAD3 SMAD3 CHRD CHRD OGT OGT AXIN1 AXIN1 TGFBR3 TGFBR3 WASF1 WASF1 SHISA2 SHISA2 XDH XDH GRB10 GRB10 SAP130 SAP130 PIK3CB PIK3CB MEN1 MEN1 SMURF2 SMURF2 SIN3A SIN3A CCN1 CCN1 LRIT3 LRIT3 KCP KCP FSTL3 FSTL3 HTRA3 HTRA3 CTNNB1 CTNNB1 DAB2 DAB2 BMP4 BMP4 SKOR1 SKOR1 NOTCH2 NOTCH2 ZBTB7A ZBTB7A STRAP STRAP TNFAIP6 TNFAIP6 LDLRAD4 LDLRAD4 VWC2L VWC2L SOSTDC1 SOSTDC1 SPRY1 SPRY1 TGFBR3L TGFBR3L MPP5 MPP5 AGT AGT AGTR2 AGTR2 SKOR2 SKOR2 HGS HGS SPRY3 SPRY3 NEO1 NEO1 LINGO3 LINGO3 ATP2B4 ATP2B4 SOX11 SOX11 GLG1 GLG1 NREP NREP ZNF703 ZNF703 VASN VASN TGFB3 TGFB3 C10H20orf27 C10H20orf27 UBE2O UBE2O NOG NOG EMILIN1 EMILIN1 MT3 MT3 SKIL SKIL ENSMFAP00000014529 ENSMFAP00000014529 CADM4 CADM4 FOLR1 FOLR1 WFIKKN1 WFIKKN1 GREM2 GREM2 FST FST ZEB2 ZEB2 PDPK1 PDPK1 PRKCB PRKCB CREB3L1 CREB3L1 SPRED2 SPRED2 RNF111 RNF111 LTBP4 LTBP4 ENSMFAP00000016148 ENSMFAP00000016148 SORL1 SORL1 FGF1 FGF1 SPRED3 SPRED3 ENSMFAP00000017173 ENSMFAP00000017173 PPARA PPARA RGMA RGMA SPRED1 SPRED1 TMEM108 TMEM108 GPC1 GPC1 GDF2 GDF2 DOK5 DOK5 SKI SKI BMPR2 BMPR2 KIAA1324L KIAA1324L TMEM204 TMEM204 HIF1A HIF1A ONECUT2 ONECUT2 HRG HRG ITGA8 ITGA8 CXCL13 CXCL13 IL12A IL12A PCSK6 PCSK6 NRP1 NRP1 THBS1 THBS1 ASPN ASPN SPART SPART PTPN1 PTPN1 GATA4 GATA4 SPRY4 SPRY4 SFRP1 SFRP1 PBLD PBLD SMURF1 SMURF1 LATS2 LATS2 NEDD4 NEDD4 TMPRSS6 TMPRSS6 SULF2 SULF2 SCUBE3 SCUBE3 CHST11 CHST11 SLIT2 SLIT2 HDAC2 HDAC2 TGFB1 TGFB1 BRMS1 BRMS1 HJV HJV PMEPA1 PMEPA1 DMD DMD SOST SOST LRP2 LRP2 FGF4 FGF4 LRG1 LRG1 WFIKKN2 WFIKKN2 SMAD2 SMAD2 HTRA4 HTRA4 PPP2R5B PPP2R5B FBN2 FBN2 CHRDL2 CHRDL2 SPINT3 SPINT3 ADAMTS12 ADAMTS12 STUB1 STUB1 CRB2 CRB2 ZDHHC17 ZDHHC17 MMRN2 MMRN2 CIDEA CIDEA GIPC1 GIPC1 DAB2IP DAB2IP ZEB1 ZEB1 GATA3 GATA3 GIPC2 GIPC2 FGF9 FGF9 NRROS NRROS ITGA5 ITGA5 NUMA1 NUMA1 GDF5 GDF5 SFRP5 SFRP5 NPTN NPTN SMAD4 SMAD4 ROBO1 ROBO1 ENSMFAP00000032703 ENSMFAP00000032703 HHEX HHEX FUZ FUZ FGF10 FGF10 VEGFC VEGFC NIBAN2 NIBAN2 SMOC2 SMOC2 HHIP HHIP FERMT1 FERMT1 WNT5A WNT5A RUNX2 RUNX2 TWSG1 TWSG1 VWC2 VWC2 SLC2A10 SLC2A10 FZD4 FZD4 CREBBP CREBBP IL17RD IL17RD ENG ENG WNT1 WNT1 FKBP8 FKBP8 FLCN FLCN DCN DCN FGFR1 FGFR1 NBL1 NBL1 SNX25 SNX25 CER1 CER1 SAP30 SAP30 BRMS1L BRMS1L ENSMFAP00000037561 ENSMFAP00000037561 SDCBP SDCBP ENSMFAP00000037907 ENSMFAP00000037907 DSTYK DSTYK DKK1 DKK1 FGF18 FGF18 TP53 TP53 CTDSPL2 CTDSPL2 CYFIP1 CYFIP1 SFRP2 SFRP2 NRXN1 NRXN1 HSP90AB1 HSP90AB1 CAV3 CAV3 PRKD2 PRKD2 BCL9L BCL9L WNT4 WNT4 EPN2 EPN2 TBX20 TBX20 DNM2 DNM2 SIRT1 SIRT1 TFAP2B TFAP2B NF1 NF1 CAV1 CAV1 NKX2-1 NKX2-1 ENSMFAP00000041061 ENSMFAP00000041061 TRIM33 TRIM33 SEMA6A SEMA6A SLC9A6 SLC9A6 TGFB1I1 TGFB1I1 HOXA13 HOXA13 HSPA5 HSPA5 ACVRL1 ACVRL1 PIN1 PIN1 SFRP4 SFRP4 ITGB3 ITGB3 DLX1 DLX1 ENSMFAP00000042475 ENSMFAP00000042475 LATS1 LATS1 GDF3 GDF3 CHRDL1 CHRDL1 DLL1 DLL1 ADAM17 ADAM17 ARNT ARNT MSX1 MSX1 FBN1 FBN1 ENSMFAP00000043889 ENSMFAP00000043889 BMPER BMPER DAND5 DAND5 EP300 EP300 ABL1 ABL1 SAP30L SAP30L ENSMFAP00000045669 ENSMFAP00000045669 RNF165 RNF165 PELO PELO NOTCH1 NOTCH1 MTMR4 MTMR4 CD63 CD63 OTX2 OTX2 SNW1 SNW1 CCBE1 CCBE1 PRDM16 PRDM16 SPRY2 SPRY2 MYOCD MYOCD XBP1 XBP1 FBXL15 FBXL15 EID2 EID2 RASL11B RASL11B CITED2 CITED2 BAMBI BAMBI CDKN1C CDKN1C CDH5 CDH5 HIPK2 HIPK2 JCAD JCAD PPM1A PPM1A LEMD3 LEMD3 RBPMS2 RBPMS2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ING2Inhibitor of growth protein. (280 aa)
PTP4A3Protein tyrosine phosphatase 4A3. (173 aa)
SMAD6Mothers against decapentaplegic homolog. (496 aa)
ZNF423Zinc finger protein 423. (1316 aa)
UBL3Ubiquitin-like protein. (117 aa)
PRDM14PR/SET domain 14. (571 aa)
IL17FInterleukin 17F. (163 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1063 aa)
GATA6GATA binding protein 6. (557 aa)
CD109CD109 molecule. (1444 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
HTRA1HtrA serine peptidase 1. (481 aa)
TET1Tet methylcytosine dioxygenase 1. (2132 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1683 aa)
ENSMFAP00000025331Uncharacterized protein. (259 aa)
ARID4BAT-rich interaction domain 4B. (1314 aa)
BMP2Bone morphogenetic protein 2. (544 aa)
NGFRNerve growth factor receptor. (427 aa)
ING1Inhibitor of growth protein. (417 aa)
FAM89BFamily with sequence similarity 89 member B. (154 aa)
ZNF451Zinc finger protein 451. (1061 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
LOXLysyl oxidase. (417 aa)
CDKN2AANK_REP_REGION domain-containing protein. (160 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (869 aa)
ADAMTS3ADAM metallopeptidase with thrombospondin type 1 motif 3. (1205 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1064 aa)
VEPH1Ventricular zone expressed PH domain containing 1. (833 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
DKK3Dickkopf_N domain-containing protein. (387 aa)
CRIM1Cysteine rich transmembrane BMP regulator 1. (1040 aa)
GIPC3GIPC PDZ domain containing family member 3. (312 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (926 aa)
SMAD7Mothers against decapentaplegic homolog. (495 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (584 aa)
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1340 aa)
ADAMTSL2ADAMTS like 2. (1049 aa)
LEMD2LEM domain containing 2. (493 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
CHRDChordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (955 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
AXIN1Axin 1. (867 aa)
TGFBR3Transforming growth factor beta receptor 3. (851 aa)
WASF1WASP family member 1. (559 aa)
SHISA2Shisa family member 2. (295 aa)
XDHXanthine dehydrogenase. (1333 aa)
GRB10Growth factor receptor bound protein 10. (593 aa)
SAP130Sin3A associated protein 130. (1083 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1072 aa)
MEN1Menin 1. (615 aa)
SMURF2E3 ubiquitin-protein ligase. (748 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
CCN1Cellular communication network factor 1. (381 aa)
LRIT3Leucine rich repeat, Ig-like and transmembrane domains 3. (676 aa)
KCPKielin cysteine rich BMP regulator. (1630 aa)
FSTL3Follistatin like 3. (154 aa)
HTRA3HtrA serine peptidase 3. (453 aa)
CTNNB1Catenin beta 1. (781 aa)
DAB2DAB adaptor protein 2. (770 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
SKOR1SKI family transcriptional corepressor 1. (964 aa)
NOTCH2Notch receptor 2. (2610 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (584 aa)
STRAPWD_REPEATS_REGION domain-containing protein. (363 aa)
TNFAIP6TNF alpha induced protein 6. (277 aa)
LDLRAD4Uncharacterized protein. (306 aa)
VWC2LVon Willebrand factor C domain-containing protein 2-like; May play a role in neurogenesis. May play a role in bone differentiation and matrix mineralization. (222 aa)
SOSTDC1Sclerostin domain containing 1. (230 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
TGFBR3LTransforming growth factor beta receptor 3 like. (312 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
AGTSERPIN domain-containing protein; Belongs to the serpin family. (485 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
SKOR2SKI family transcriptional corepressor 2. (911 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (830 aa)
SPRY3Sprouty RTK signaling antagonist 3. (288 aa)
NEO1Neogenin 1. (1434 aa)
LINGO3Leucine rich repeat and Ig domain containing 3. (592 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
SOX11Transcription factor SOX. (441 aa)
GLG1Golgi glycoprotein 1. (1203 aa)
NREPNeuronal regeneration-related protein; May have roles in neural function and cellular differentiation. Ectopic expression promotes axonal regeneration, induces differentiation of fibroblast into myofibroblast, induces myofibroblast ameboid migration, augments motility of gliomas, and increases retinoic-acid regulation of lipid-droplet biogenesis. Down- regulates the expression of TGFB1 and TGFB2 but not of TGFB3. May play a role in the regulation of alveolar generation. (112 aa)
ZNF703Zinc finger protein 703. (591 aa)
VASNVasorin. (673 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
C10H20orf27Uncharacterized protein. (199 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1293 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
EMILIN1Elastin microfibril interfacer 1. (1016 aa)
MT3Metallothionein-3; Binds heavy metals. Contains five zinc and one copper atoms per polypeptide chain and only a negligible amount of cadmium (By similarity). (113 aa)
SKILSKI like proto-oncogene. (684 aa)
ENSMFAP00000014529Uncharacterized protein. (106 aa)
CADM4Cell adhesion molecule 4. (391 aa)
FOLR1Folate receptor alpha. (257 aa)
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa)
GREM2Gremlin. (168 aa)
FSTFollistatin. (344 aa)
ZEB2Zinc finger E-box binding homeobox 2. (1253 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (510 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (645 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
SPRED2Sprouty related EVH1 domain containing 2. (432 aa)
RNF111Ring finger protein 111. (1002 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1624 aa)
ENSMFAP00000016148PPM-type phosphatase domain-containing protein. (280 aa)
SORL1Sortilin related receptor 1. (2212 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
SPRED3Sprouty related EVH1 domain containing 3. (424 aa)
ENSMFAP00000017173PDZ domain-containing protein. (255 aa)
PPARAPeroxisome proliferator activated receptor alpha. (467 aa)
RGMARepulsive guidance molecule A; Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA- ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG- PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition. Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inacti [...] (458 aa)
SPRED1Sprouty related EVH1 domain containing 1. (444 aa)
TMEM108Transmembrane protein 108. (575 aa)
GPC1Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa)
GDF2Growth differentiation factor 2. (429 aa)
DOK5Docking protein 5. (306 aa)
SKISKI proto-oncogene. (681 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
KIAA1324LKIAA1324 like. (1029 aa)
TMEM204Transmembrane protein 204. (226 aa)
HIF1AUncharacterized protein. (831 aa)
ONECUT2One cut domain family member. (481 aa)
HRGHistidine rich glycoprotein. (525 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
CXCL13C-X-C motif chemokine. (109 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (944 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
THBS1Thrombospondin 1. (1173 aa)
ASPNAsporin. (333 aa)
SPARTSpartin. (666 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
GATA4GATA binding protein 4. (425 aa)
SPRY4Sprouty RTK signaling antagonist 4. (322 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
PBLDPhenazine biosynthesis like protein domain containing. (288 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
LATS2Large tumor suppressor kinase 2. (911 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1319 aa)
TMPRSS6Transmembrane serine protease 6; Belongs to the peptidase S1 family. (821 aa)
SULF2Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (951 aa)
SCUBE3Signal peptide, CUB domain and EGF like domain containing 3. (993 aa)
CHST11Carbohydrate sulfotransferase. (352 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
BRMS1Uncharacterized protein. (262 aa)
HJVHemojuvelin BMP co-receptor. (427 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (287 aa)
DMDDystrophin. (3685 aa)
SOSTSclerostin. (213 aa)
LRP2LDL receptor related protein 2. (4655 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
LRG1Leucine rich alpha-2-glycoprotein 1. (347 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (576 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
HTRA4HtrA serine peptidase 4. (476 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
FBN2Fibrillin 2. (2912 aa)
CHRDL2Chordin like 2. (452 aa)
SPINT3Serine peptidase inhibitor, Kunitz type 3. (89 aa)
ADAMTS12ADAM metallopeptidase with thrombospondin type 1 motif 12. (1598 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
CRB2Crumbs cell polarity complex component 2. (1350 aa)
ZDHHC17Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (632 aa)
MMRN2Multimerin 2. (951 aa)
CIDEACell death inducing DFFA like effector a. (219 aa)
GIPC1GIPC PDZ domain containing family member 1. (333 aa)
DAB2IPDAB2 interacting protein. (1153 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1127 aa)
GATA3GATA binding protein 3. (444 aa)
GIPC2GIPC PDZ domain containing family member 2. (315 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
NRROSNegative regulator of reactive oxygen species. (732 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1098 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2133 aa)
GDF5Growth differentiation factor 5. (499 aa)
SFRP5Secreted frizzled related protein 5. (315 aa)
NPTNNeuroplastin. (398 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ROBO1Roundabout guidance receptor 1. (1651 aa)
ENSMFAP00000032703Uncharacterized protein. (103 aa)
HHEXHematopoietically expressed homeobox. (270 aa)
FUZFuzzy planar cell polarity protein. (418 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (420 aa)
NIBAN2Niban apoptosis regulator 2. (746 aa)
SMOC2SPARC related modular calcium binding 2. (330 aa)
HHIPHedgehog interacting protein. (682 aa)
FERMT1Fermitin family member 1. (677 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
RUNX2RUNX family transcription factor 2. (627 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
SLC2A10Solute carrier family 2 member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (555 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (524 aa)
CREBBPCREB binding protein. (2442 aa)
IL17RDInterleukin 17 receptor D. (739 aa)
ENGEndoglin. (555 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
FKBP8Peptidylprolyl isomerase. (413 aa)
FLCNFolliculin. (579 aa)
DCNDecorin; May affect the rate of fibrils formation. (359 aa)
FGFR1Fibroblast growth factor receptor. (820 aa)
NBL1NBL1, DAN family BMP antagonist. (216 aa)
SNX25Sorting nexin 25. (879 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
SAP30Sin3A associated protein 30. (220 aa)
BRMS1LBRMS1 like transcriptional repressor. (323 aa)
ENSMFAP00000037561Uncharacterized protein. (115 aa)
SDCBPUncharacterized protein. (324 aa)
ENSMFAP00000037907Fork-head domain-containing protein. (260 aa)
DSTYKDual serine/threonine and tyrosine protein kinase. (931 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (393 aa)
CTDSPL2CTD small phosphatase like 2. (466 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1232 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
NRXN1Neurexin 1. (1507 aa)
HSP90AB1Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] (724 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
BCL9LBCL9 like. (1500 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
EPN2Epsin 2. (641 aa)
TBX20T-box transcription factor 20. (447 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
SIRT1Sirtuin 1. (743 aa)
TFAP2BTranscription factor AP-2 beta. (469 aa)
NF1Neurofibromin 1. (2849 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
NKX2-1NK2 homeobox 1. (448 aa)
ENSMFAP00000041061TPR_REGION domain-containing protein. (134 aa)
TRIM33Tripartite motif containing 33. (1127 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
SLC9A6Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (701 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (467 aa)
HOXA13Homeobox A13. (228 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
PIN1Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis/trans isomerase (PPIase) that binds to and isomerizes specific phosphorylated Ser/Thr-Pro (pSer/Thr-Pro) motifs. By inducing conformational changes in a subset of phosphorylated proteins, acts as a molecular switch in multiple cellular processes. Displays a preference for acidic residues located N-terminally to the proline bond to be isomerized. Regulates mitosis presumably by interacting with NIMA and attenuating its mitosis- promoting activity. Down-regulates kinase activity of BTK. Can transactivate multiple [...] (145 aa)
SFRP4Secreted frizzled related protein 4. (368 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
DLX1Homeobox domain-containing protein. (255 aa)
ENSMFAP00000042475Uncharacterized protein. (290 aa)
LATS1Large tumor suppressor kinase 1. (1130 aa)
GDF3Growth differentiation factor 3. (364 aa)
CHRDL1Chordin like 1. (458 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (789 aa)
MSX1Msh homeobox 1. (303 aa)
FBN1Fibrillin 1. (2871 aa)
ENSMFAP00000043889Uncharacterized protein; Belongs to the heat shock protein 70 family. (619 aa)
BMPERBMP binding endothelial regulator. (685 aa)
DAND5DAN domain BMP antagonist family member 5. (189 aa)
EP300E1A binding protein p300. (2414 aa)
ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase. (901 aa)
SAP30LSAP30 like. (184 aa)
ENSMFAP00000045669SKIP_SNW domain-containing protein. (467 aa)
RNF165Ring finger protein 165. (346 aa)
PELOProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
NOTCH1Notch receptor 1. (2556 aa)
MTMR4Myotubularin related protein 4. (1195 aa)
CD63Tetraspanin. (238 aa)
OTX2Orthodenticle homeobox 2. (297 aa)
SNW1SNW domain containing 1. (571 aa)
CCBE1Collagen and calcium binding EGF domains 1. (406 aa)
PRDM16PR/SET domain 16. (1276 aa)
SPRY2Protein sprouty homolog 2; May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis. (338 aa)
MYOCDMyocardin. (964 aa)
XBP1BZIP domain-containing protein. (380 aa)
FBXL15F-box and leucine rich repeat protein 15. (300 aa)
EID2EP300 interacting inhibitor of differentiation 2. (236 aa)
RASL11BRAS like family 11 member B. (248 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
CDKN1CUncharacterized protein. (215 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
HIPK2Homeodomain interacting protein kinase 2. (1196 aa)
JCADJunctional cadherin 5 associated. (1356 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
LEMD3LEM domain containing 3. (909 aa)
RBPMS2RNA binding protein, mRNA processing factor 2. (209 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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