STRINGSTRING
IMPACT IMPACT ENSMFAP00000034212 ENSMFAP00000034212 ENSMFAP00000034629 ENSMFAP00000034629 ATF4 ATF4 EIF2AK1 EIF2AK1 BATF2 BATF2 DELE1 DELE1 NFE2L2 NFE2L2 CEBPB CEBPB EIF2S1 EIF2S1 ENSMFAP00000036680 ENSMFAP00000036680 CEBPE CEBPE EIF2AK4 EIF2AK4 OMA1 OMA1 BATF3 BATF3 EIF2AK3 EIF2AK3 NFE2L3 NFE2L3 BATF BATF TMED2 TMED2 ENSMFAP00000001570 ENSMFAP00000001570 JUNB JUNB QRICH1 QRICH1 CEBPG CEBPG CEBPA CEBPA FOS FOS CEBPD CEBPD NFE2 NFE2 CREB3 CREB3 FOSL1 FOSL1 DDIT3 DDIT3 CREBZF CREBZF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IMPACTRWD domain-containing protein. (320 aa)
ENSMFAP00000034212RWD domain-containing protein. (293 aa)
ENSMFAP00000034629Uncharacterized protein. (122 aa)
ATF4Activating transcription factor 4. (351 aa)
EIF2AK1Eukaryotic translation initiation factor 2-alpha kinase 1; Inhibits protein synthesis at the translation initiation level, in response to various stress conditions, including oxidative stress, heme deficiency, osmotic shock and heat shock. Exerts its function through the phosphorylation of EIF2S1 at 'Ser-48' and 'Ser- 51', thus preventing its recycling. Binds hemin forming a 1:1 complex through a cysteine thiolate and histidine nitrogenous coordination. This binding occurs with moderate affinity, allowing it to sense the heme concentration within the cell. Thanks to this unique heme-se [...] (631 aa)
BATF2Basic leucine zipper ATF-like transcription factor 2. (273 aa)
DELE1DAP3 binding cell death enhancer 1. (522 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
CEBPBCCAAT/enhancer-binding protein. (314 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
ENSMFAP00000036680RWD domain-containing protein. (136 aa)
CEBPECCAAT/enhancer-binding protein. (281 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1248 aa)
OMA1Peptidase_M48 domain-containing protein. (524 aa)
BATF3Basic leucine zipper ATF-like transcription factor 3. (139 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa)
NFE2L3Nuclear factor, erythroid 2 like 3. (693 aa)
BATFBasic leucine zipper ATF-like transcription factor. (125 aa)
TMED2GOLD domain-containing protein. (208 aa)
ENSMFAP00000001570GOLD domain-containing protein. (188 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
QRICH1Glutamine rich 1. (777 aa)
CEBPGCCAAT enhancer binding protein gamma. (150 aa)
CEBPACCAAT enhancer binding protein alpha. (198 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
CEBPDCCAAT/enhancer-binding protein. (265 aa)
NFE2Nuclear factor, erythroid 2. (373 aa)
CREB3cAMP responsive element binding protein 3. (372 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
CREBZFCREB/ATF bZIP transcription factor. (357 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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