26 items (Macaca fascicularis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Your Input:
	NR1H4	Nuclear receptor subfamily 1 group H member 4. (486 aa)
	OSBPL8	Oxysterol-binding protein; Belongs to the OSBP family. (902 aa)
	ENSMFAP00000028626	Uncharacterized protein. (154 aa)
	SERPINA12	Serpin family A member 12; Belongs to the serpin family. (414 aa)
	ENSMFAP00000043772	Uncharacterized protein. (457 aa)
	IRS1	Insulin receptor substrate 1. (1241 aa)
	ENSMFAP00000042269	Uncharacterized protein. (147 aa)
	SNX5	Sorting nexin; Involved in several stages of intracellular trafficking. (405 aa)
	ECHDC3	Enoyl-CoA hydratase domain containing 3. (303 aa)
	NUCKS1	Nuclear casein kinase and cyclin dependent kinase substrate 1. (243 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	C1QTNF12	C1q and TNF related 12. (177 aa)
	SIRT1	Sirtuin 1. (743 aa)
	PRKCZ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (583 aa)
	ERFE	Erythroferrone. (354 aa)
	ENSMFAP00000031517	Uncharacterized protein. (262 aa)
	ZBTB7B	Zinc finger and BTB domain containing 7B. (573 aa)
	MYO1C	Myosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1063 aa)
	IGF2	Insulin like growth factor 2. (183 aa)
	ESRRA	Estrogen related receptor alpha. (422 aa)
	ENSMFAP00000021707	Nuclear receptor domain-containing protein. (255 aa)
	SRC	Tyrosine-protein kinase. (542 aa)
	SORBS1	Sorbin and SH3 domain containing 1. (1294 aa)
	SORL1	Sortilin related receptor 1. (2212 aa)
	ENSMFAP00000015614	Uncharacterized protein. (506 aa)
	GKAP1	G kinase anchoring protein 1. (366 aa)

Your Current Organism:

Macaca fascicularis

NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMFAP00000015614	IRS1	ENSMFAP00000015614	ENSMFAP00000042443	Uncharacterized protein.	Insulin receptor substrate 1.	0.870
ENSMFAP00000015614	SRC	ENSMFAP00000015614	ENSMFAP00000018120	Uncharacterized protein.	Tyrosine-protein kinase.	0.652
ENSMFAP00000031517	IRS1	ENSMFAP00000031517	ENSMFAP00000042443	Uncharacterized protein.	Insulin receptor substrate 1.	0.627
ENSMFAP00000031517	SRC	ENSMFAP00000031517	ENSMFAP00000018120	Uncharacterized protein.	Tyrosine-protein kinase.	0.563
ENSMFAP00000043772	IRS1	ENSMFAP00000043772	ENSMFAP00000042443	Uncharacterized protein.	Insulin receptor substrate 1.	0.870
ENSMFAP00000043772	SRC	ENSMFAP00000043772	ENSMFAP00000018120	Uncharacterized protein.	Tyrosine-protein kinase.	0.652
IGF2	IRS1	ENSMFAP00000026325	ENSMFAP00000042443	Insulin like growth factor 2.	Insulin receptor substrate 1.	0.678
IRS1	ENSMFAP00000015614	ENSMFAP00000042443	ENSMFAP00000015614	Insulin receptor substrate 1.	Uncharacterized protein.	0.870
IRS1	ENSMFAP00000031517	ENSMFAP00000042443	ENSMFAP00000031517	Insulin receptor substrate 1.	Uncharacterized protein.	0.627
IRS1	ENSMFAP00000043772	ENSMFAP00000042443	ENSMFAP00000043772	Insulin receptor substrate 1.	Uncharacterized protein.	0.870
IRS1	IGF2	ENSMFAP00000042443	ENSMFAP00000026325	Insulin receptor substrate 1.	Insulin like growth factor 2.	0.678
IRS1	PRKCZ	ENSMFAP00000042443	ENSMFAP00000037413	Insulin receptor substrate 1.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.924
IRS1	PTPN11	ENSMFAP00000042443	ENSMFAP00000040325	Insulin receptor substrate 1.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.986
IRS1	SIRT1	ENSMFAP00000042443	ENSMFAP00000039959	Insulin receptor substrate 1.	Sirtuin 1.	0.553
IRS1	SRC	ENSMFAP00000042443	ENSMFAP00000018120	Insulin receptor substrate 1.	Tyrosine-protein kinase.	0.721
PRKCZ	IRS1	ENSMFAP00000037413	ENSMFAP00000042443	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Insulin receptor substrate 1.	0.924
PRKCZ	SRC	ENSMFAP00000037413	ENSMFAP00000018120	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Tyrosine-protein kinase.	0.418
PTPN11	IRS1	ENSMFAP00000040325	ENSMFAP00000042443	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Insulin receptor substrate 1.	0.986
PTPN11	SRC	ENSMFAP00000040325	ENSMFAP00000018120	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein kinase.	0.652
SIRT1	IRS1	ENSMFAP00000039959	ENSMFAP00000042443	Sirtuin 1.	Insulin receptor substrate 1.	0.553

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