STRINGSTRING
SVIP SVIP HSPA5 HSPA5 BFAR BFAR ERN1 ERN1 WFS1 WFS1 USP19 USP19 PPP1R15B PPP1R15B BCL2L11 BCL2L11 ENSMFAP00000043889 ENSMFAP00000043889 USP25 USP25 BOK BOK NR1H2 NR1H2 NR1H3 NR1H3 PRKN PRKN DNAJB9 DNAJB9 SYVN1 SYVN1 CREBRF CREBRF TMEM259 TMEM259 ATF6B ATF6B USP13 USP13 SELENOS SELENOS USP14 USP14 ERP29 ERP29 ALOX5 ALOX5 ENSMFAP00000012933 ENSMFAP00000012933 NUPR1 NUPR1 BAK1 BAK1 ENSMFAP00000015013 ENSMFAP00000015013 CREB3L1 CREB3L1 ENSMFAP00000016059 ENSMFAP00000016059 EIF2AK3 EIF2AK3 GRINA GRINA ENSMFAP00000019793 ENSMFAP00000019793 ENSMFAP00000020087 ENSMFAP00000020087 PTPN1 PTPN1 RNFT2 RNFT2 BAX BAX BBC3 BBC3 OPA1 OPA1 NCK2 NCK2 ENSMFAP00000021271 ENSMFAP00000021271 AGR2 AGR2 PDX1 PDX1 ENSMFAP00000022286 ENSMFAP00000022286 TMEM33 TMEM33 MANF MANF ATXN3 ATXN3 PTPN2 PTPN2 BCL2L1 BCL2L1 CREB3 CREB3 NCK1 NCK1 RNFT1 RNFT1 SERINC3 SERINC3 DDIT3 DDIT3 PIK3R1 PIK3R1 UBXN1 UBXN1 XBP1 XBP1 LRRK2 LRRK2 LPCAT3 LPCAT3 BAG6 BAG6 AQP11 AQP11 HYOU1 HYOU1 ENSMFAP00000028396 ENSMFAP00000028396 CLU CLU PPP1R15A PPP1R15A PARK7 PARK7 DAB2IP DAB2IP RNF185 RNF185 TXNDC12 TXNDC12 ENSMFAP00000031774 ENSMFAP00000031774 ABCA7 ABCA7 HERPUD1 HERPUD1 SGTA SGTA FICD FICD COPS5 COPS5 DDRGK1 DDRGK1 UFL1 UFL1 ATF6 ATF6 SIRT1 SIRT1 CAV1 CAV1 NFE2L2 NFE2L2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SVIPSmall VCP interacting protein. (77 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
BFARBifunctional apoptosis regulator. (450 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (978 aa)
WFS1Wolframin ER transmembrane glycoprotein. (890 aa)
USP19Ubiquitin specific peptidase 19. (1421 aa)
PPP1R15BProtein phosphatase 1 regulatory subunit 15B. (710 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
ENSMFAP00000043889Uncharacterized protein; Belongs to the heat shock protein 70 family. (619 aa)
USP25Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family. (1125 aa)
BOKBCL2 family apoptosis regulator BOK. (212 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (461 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (453 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
DNAJB9J domain-containing protein. (222 aa)
SYVN1Synoviolin 1. (617 aa)
CREBRFBZIP domain-containing protein. (642 aa)
TMEM259Transmembrane protein 259. (632 aa)
ATF6BActivating transcription factor 6 beta. (708 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (863 aa)
SELENOSSelenoprotein S. (211 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (493 aa)
ERP29Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase. (261 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
ENSMFAP00000012933Uncharacterized protein. (209 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (100 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
ENSMFAP00000015013Uncharacterized protein. (140 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
ENSMFAP00000016059Uncharacterized protein. (54 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa)
GRINAGlutamate ionotropic receptor NMDA type subunit associated protein 1. (371 aa)
ENSMFAP00000019793DJ-1_PfpI domain-containing protein. (134 aa)
ENSMFAP00000020087Josephin domain-containing protein. (314 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
RNFT2Ring finger protein, transmembrane 2. (436 aa)
BAXBCL2 associated X, apoptosis regulator. (203 aa)
BBC3BCL2 binding component 3. (261 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1015 aa)
NCK2Cytoplasmic protein. (382 aa)
ENSMFAP00000021271Uncharacterized protein. (54 aa)
AGR2Anterior gradient 2, protein disulphide isomerase family member. (175 aa)
PDX1Pancreatic and duodenal homeobox 1. (282 aa)
ENSMFAP00000022286Uncharacterized protein. (156 aa)
TMEM33Transmembrane protein 33. (247 aa)
MANFMesencephalic astrocyte derived neurotrophic factor. (182 aa)
ATXN3Josephin domain-containing protein. (375 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (415 aa)
BCL2L1BCL2 like 1. (233 aa)
CREB3cAMP responsive element binding protein 3. (372 aa)
NCK1Cytoplasmic protein. (377 aa)
RNFT1Ring finger protein, transmembrane 1. (435 aa)
SERINC3Serine incorporator 3. (473 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
UBXN1UBX domain protein 1. (310 aa)
XBP1BZIP domain-containing protein. (380 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
LPCAT3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (487 aa)
BAG6BCL2 associated athanogene 6. (1132 aa)
AQP11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
HYOU1Hypoxia up-regulated 1. (999 aa)
ENSMFAP00000028396DJ-1_PfpI domain-containing protein. (166 aa)
CLUClusterin; Belongs to the clusterin family. (501 aa)
PPP1R15AProtein phosphatase 1 regulatory subunit 15A. (675 aa)
PARK7DJ-1_PfpI domain-containing protein. (189 aa)
DAB2IPDAB2 interacting protein. (1153 aa)
RNF185Ring finger protein 185. (192 aa)
TXNDC12Thioredoxin domain containing 12. (172 aa)
ENSMFAP00000031774DJ-1_PfpI domain-containing protein. (133 aa)
ABCA7ATP binding cassette subfamily A member 7. (2148 aa)
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (391 aa)
SGTASmall glutamine rich tetratricopeptide repeat containing alpha. (313 aa)
FICDFIC domain containing. (460 aa)
COPS5COP9 signalosome subunit 5. (334 aa)
DDRGK1DDRGK domain containing 1. (342 aa)
UFL1E3 UFM1-protein ligase 1; E3 protein ligase that mediates ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins, a post-translational modification on lysine residues of proteins that may play a crucial role in a number of cellular processes. Mediates DDRGK1 ufmylation and may regulate the proteasomal degradation of DDRGK1 and CDK5RAP3 thereby modulating NF-kappa-B signaling. May also play a role in nuclear receptor-mediated transcription through TRIP4 ufmylation. May play a role in the unfolded protein response, mediating the ufmylation of multip [...] (793 aa)
ATF6Activating transcription factor 6. (669 aa)
SIRT1Sirtuin 1. (743 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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