45 items (Macaca fascicularis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FNBP1	Formin binding protein 1. (622 aa)
	DGKD	Diacylglycerol kinase. (1209 aa)
	ENSMFAP00000033774	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (551 aa)
	SH3BP4	SH3 domain binding protein 4. (963 aa)
	REPS1	RALBP1 associated Eps domain containing 1. (796 aa)
	DNM2	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
	TNK2	Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1069 aa)
	EPN1	Epsin 1. (662 aa)
	ENSMFAP00000042433	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (508 aa)
	AP1S3	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (164 aa)
	EPS15L1	Epidermal growth factor receptor pathway substrate 15 like 1. (910 aa)
	ATAT1	Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] (413 aa)
	LRP1	LDL receptor related protein 1. (4544 aa)
	ENSMFAP00000045795	Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (209 aa)
	TFRC	Transferrin receptor. (760 aa)
	CTTN	Cortactin. (550 aa)
	AP2S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
	AP2M1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (458 aa)
	SYNJ1	Synaptojanin 1. (1548 aa)
	SLC18A3	Solute carrier family 18 member A3. (532 aa)
	SELE	Selectin E. (612 aa)
	DAB2	DAB adaptor protein 2. (770 aa)
	AP1S2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
	ENSMFAP00000000934	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (503 aa)
	RAB35	RAB35, member RAS oncogene family. (201 aa)
	ACKR3	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	AP1S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (157 aa)
	CDCP2	CUB domain containing protein 2. (540 aa)
	FCHO2	FCH domain only 2. (815 aa)
	AP2A2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (940 aa)
	TF	Transferrin; Belongs to the transferrin family. (698 aa)
	ENSMFAP00000018887	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (315 aa)
	SPHK1	Sphingosine kinase 1. (470 aa)
	AAK1	AP2 associated kinase 1. (962 aa)
	AP2B1	AP complex subunit beta. (951 aa)
	HSPD1	Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (598 aa)
	SORT1	Sortilin. (831 aa)
	ITSN1	Intersectin 1. (1625 aa)
	EPS15	Epidermal growth factor receptor pathway substrate 15. (898 aa)
	SGIP1	SH3 domain GRB2 like endophilin interacting protein 1. (859 aa)
	LRP2	LDL receptor related protein 2. (4655 aa)
	FCHO1	FCH domain only 1. (870 aa)
	ITSN2	Intersectin 2. (1697 aa)
	AP2A1	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (977 aa)

Your Current Organism:

Macaca fascicularis

NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAK1	AP2A1	ENSMFAP00000019490	ENSMFAP00000030277	AP2 associated kinase 1.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.643
AAK1	AP2B1	ENSMFAP00000019490	ENSMFAP00000019893	AP2 associated kinase 1.	AP complex subunit beta.	0.721
AAK1	AP2M1	ENSMFAP00000019490	ENSMFAP00000012689	AP2 associated kinase 1.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.837
AAK1	AP2S1	ENSMFAP00000019490	ENSMFAP00000012836	AP2 associated kinase 1.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.763
AAK1	DAB2	ENSMFAP00000019490	ENSMFAP00000007888	AP2 associated kinase 1.	DAB adaptor protein 2.	0.417
AAK1	EPS15	ENSMFAP00000019490	ENSMFAP00000025246	AP2 associated kinase 1.	Epidermal growth factor receptor pathway substrate 15.	0.830
AAK1	EPS15L1	ENSMFAP00000019490	ENSMFAP00000045671	AP2 associated kinase 1.	Epidermal growth factor receptor pathway substrate 15 like 1.	0.776
AAK1	FCHO1	ENSMFAP00000019490	ENSMFAP00000029332	AP2 associated kinase 1.	FCH domain only 1.	0.684
AAK1	FCHO2	ENSMFAP00000019490	ENSMFAP00000015453	AP2 associated kinase 1.	FCH domain only 2.	0.487
AAK1	ITSN1	ENSMFAP00000019490	ENSMFAP00000025126	AP2 associated kinase 1.	Intersectin 1.	0.514
AAK1	ITSN2	ENSMFAP00000019490	ENSMFAP00000029438	AP2 associated kinase 1.	Intersectin 2.	0.688
AAK1	REPS1	ENSMFAP00000019490	ENSMFAP00000038627	AP2 associated kinase 1.	RALBP1 associated Eps domain containing 1.	0.840
AAK1	SGIP1	ENSMFAP00000019490	ENSMFAP00000028247	AP2 associated kinase 1.	SH3 domain GRB2 like endophilin interacting protein 1.	0.553
AP1S1	AP1S2	ENSMFAP00000014641	ENSMFAP00000003542	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.945
AP1S1	AP1S3	ENSMFAP00000014641	ENSMFAP00000044143	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.934
AP1S1	AP2A1	ENSMFAP00000014641	ENSMFAP00000030277	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.700
AP1S1	AP2A2	ENSMFAP00000014641	ENSMFAP00000017329	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.418
AP1S1	AP2B1	ENSMFAP00000014641	ENSMFAP00000019893	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit beta.	0.865
AP1S1	AP2M1	ENSMFAP00000014641	ENSMFAP00000012689	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.534
AP1S1	AP2S1	ENSMFAP00000014641	ENSMFAP00000012836	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.424

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