STRINGSTRING
ENSMFAP00000023078 ENSMFAP00000023078 CASP9 CASP9 BCL2L1 BCL2L1 MCL1 MCL1 CASP3 CASP3 BCL2L11 BCL2L11 BCL2 BCL2 BAK1 BAK1 ENSMFAP00000022286 ENSMFAP00000022286
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMFAP00000023078Uncharacterized protein; Belongs to the peptidase C14A family. (261 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (421 aa)
BCL2L1BCL2 like 1. (233 aa)
MCL1Uncharacterized protein. (350 aa)
CASP3Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. (277 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
BCL2BCL2 apoptosis regulator. (242 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
ENSMFAP00000022286Uncharacterized protein. (156 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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