(67 nodes) Protein complex involved in cell adhesion network (Macaca fascicularis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	NRXN1	Neurexin 1. (1507 aa)
	ITGAD	Integrin subunit alpha D; Belongs to the integrin alpha chain family. (1161 aa)
	TNR	Tenascin R. (1358 aa)
	CCL25	C-C motif chemokine ligand 25. (165 aa)
	LGALS7B	Galectin. (136 aa)
	CCR9	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (369 aa)
	MMRN1	Multimerin 1. (1223 aa)
	ITGB4	Integrin beta. (1823 aa)
	MGAT5	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase. (741 aa)
	ITGB6	Integrin beta; Belongs to the integrin beta chain family. (788 aa)
	ITGA9	Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1035 aa)
	ITGB2	Integrin beta. (874 aa)
	ITGA4	Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
	LGALS2	Galectin. (139 aa)
	ITGA11	Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1191 aa)
	ITGB5	Integrin beta; Belongs to the integrin beta chain family. (799 aa)
	ACKR2	Atypical chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (384 aa)
	NID1	Nidogen 1. (1247 aa)
	ICAM1	Intercellular adhesion molecule 1. (532 aa)
	EMILIN1	Elastin microfibril interfacer 1. (1016 aa)
	ENSMFAP00000013911	Galectin. (134 aa)
	ITGA7	Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
	ITGAM	Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1147 aa)
	TSPAN32	Tetraspanin 32; Belongs to the tetraspanin (TM4SF) family. (320 aa)
	ITGA2	Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
	ITGAX	Integrin subunit alpha X; Belongs to the integrin alpha chain family. (1168 aa)
	ITGA8	Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
	LGALS8	Galectin. (358 aa)
	CD80	CD80 molecule. (288 aa)
	VTN	SMB domain-containing protein. (479 aa)
	AASDH	Aminoadipate-semialdehyde dehydrogenase. (1098 aa)
	ITGAE	Integrin subunit alpha E; Belongs to the integrin alpha chain family. (1049 aa)
	ITGA10	Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1352 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	ITGA3	Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1064 aa)
	SVEP1	Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1. (3228 aa)
	LGALS9	Galectin. (345 aa)
	PLAUR	Urokinase plasminogen activator surface receptor; Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form (By similarity). (335 aa)
	ENSMFAP00000026155	Galectin. (87 aa)
	ITGB7	Integrin beta; Belongs to the integrin beta chain family. (798 aa)
	PMP22	Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (160 aa)
	POSTN	Periostin. (836 aa)
	GP6	Glycoprotein VI platelet. (545 aa)
	MMRN2	Multimerin 2. (951 aa)
	MORC3	MORC family CW-type zinc finger 3. (939 aa)
	JAM2	Junctional adhesion molecule 2. (311 aa)
	CTLA4	Cytotoxic T-lymphocyte associated protein 4. (223 aa)
	LAMC1	Laminin subunit gamma 1. (1608 aa)
	ITGA5	Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1098 aa)
	LGALS1	Galectin. (135 aa)
	EMILIN2	Elastin microfibril interfacer 2. (1080 aa)
	ITGAL	VWFA domain-containing protein. (582 aa)
	ITGAV	Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
	CD28	IGv domain-containing protein. (234 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (801 aa)
	ITGA1	Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
	DCN	Decorin; May affect the rate of fibrils formation. (359 aa)
	SPP1	Secreted phosphoprotein 1. (314 aa)
	ITGA6	Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
	GP1BA	Glycoprotein Ib platelet subunit alpha. (649 aa)
	NPNT	Nephronectin. (610 aa)
	MCMDC2	Minichromosome maintenance domain containing 2. (681 aa)
	TRIM33	Tripartite motif containing 33. (1127 aa)
	LAMA2	Laminin subunit alpha 2. (3122 aa)
	VWF	Von Willebrand factor. (2813 aa)
	ITGA2B	Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1039 aa)
	ITGB8	Integrin beta; Belongs to the integrin beta chain family. (769 aa)

Your Current Organism:

Macaca fascicularis

NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACKR2	CCL25	ENSMFAP00000011035	ENSMFAP00000002955	Atypical chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine ligand 25.	0.646
CCL25	ACKR2	ENSMFAP00000002955	ENSMFAP00000011035	C-C motif chemokine ligand 25.	Atypical chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.646
CCL25	CCR9	ENSMFAP00000002955	ENSMFAP00000004137	C-C motif chemokine ligand 25.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.999
CCR9	CCL25	ENSMFAP00000004137	ENSMFAP00000002955	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine ligand 25.	0.999
CCR9	CD80	ENSMFAP00000004137	ENSMFAP00000019988	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	CD80 molecule.	0.433
CCR9	ITGB7	ENSMFAP00000004137	ENSMFAP00000026257	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Integrin beta; Belongs to the integrin beta chain family.	0.519
CD28	CD80	ENSMFAP00000034788	ENSMFAP00000019988	IGv domain-containing protein.	CD80 molecule.	0.999
CD28	CTLA4	ENSMFAP00000034788	ENSMFAP00000031091	IGv domain-containing protein.	Cytotoxic T-lymphocyte associated protein 4.	0.751
CD28	ICAM1	ENSMFAP00000034788	ENSMFAP00000012895	IGv domain-containing protein.	Intercellular adhesion molecule 1.	0.648
CD28	ITGA4	ENSMFAP00000034788	ENSMFAP00000008052	IGv domain-containing protein.	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	0.502
CD28	LYN	ENSMFAP00000034788	ENSMFAP00000023353	IGv domain-containing protein.	Tyrosine-protein kinase.	0.434
CD80	CCR9	ENSMFAP00000019988	ENSMFAP00000004137	CD80 molecule.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.433
CD80	CD28	ENSMFAP00000019988	ENSMFAP00000034788	CD80 molecule.	IGv domain-containing protein.	0.999
CD80	CTLA4	ENSMFAP00000019988	ENSMFAP00000031091	CD80 molecule.	Cytotoxic T-lymphocyte associated protein 4.	0.999
CD80	ICAM1	ENSMFAP00000019988	ENSMFAP00000012895	CD80 molecule.	Intercellular adhesion molecule 1.	0.839
CD80	ITGA4	ENSMFAP00000019988	ENSMFAP00000008052	CD80 molecule.	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	0.419
CD80	ITGAL	ENSMFAP00000019988	ENSMFAP00000033538	CD80 molecule.	VWFA domain-containing protein.	0.515
CD80	ITGAM	ENSMFAP00000019988	ENSMFAP00000015971	CD80 molecule.	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	0.540
CD80	ITGAX	ENSMFAP00000019988	ENSMFAP00000019285	CD80 molecule.	Integrin subunit alpha X; Belongs to the integrin alpha chain family.	0.623
CD80	ITGB1	ENSMFAP00000019988	ENSMFAP00000036700	CD80 molecule.	Integrin beta; Belongs to the integrin beta chain family.	0.436

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