STRINGSTRING
IL10RB IL10RB HJV HJV CD247 CD247 ITGAD ITGAD RAMP2 RAMP2 GRIA2 GRIA2 AADACL3 AADACL3 GABBR1 GABBR1 IL6ST IL6ST SPN SPN IRAK1 IRAK1 CD3E CD3E CNIH3 CNIH3 STAT3 STAT3 CHRNG CHRNG CCL25 CCL25 LOC102123076 LOC102123076 ADM ADM HTR3E HTR3E FAM189A1 FAM189A1 CCR9 CCR9 NLRP13 NLRP13 LRRTM4 LRRTM4 ITGB4 ITGB4 GRIA4 GRIA4 HTR3B HTR3B TRAT1 TRAT1 CACNG5 CACNG5 NIPAL3 NIPAL3 ITGB6 ITGB6 CHRNA3 CHRNA3 IFNLR1 IFNLR1 OLFM2 OLFM2 ENSMFAP00000006091 ENSMFAP00000006091 IL5 IL5 BMPR1A BMPR1A AMHR2 AMHR2 GRIK4 GRIK4 ITGA9 ITGA9 ITGB2 ITGB2 CD5 CD5 GRIN3B GRIN3B IL13RA1 IL13RA1 GRM1 GRM1 BMP4 BMP4 ITGA4 ITGA4 CHRNA7 CHRNA7 HTR3D HTR3D ITGA11 ITGA11 CD79A CD79A CACNG7 CACNG7 HFE HFE CHRNE CHRNE TFR2 TFR2 VWC2L VWC2L LOC102139775 LOC102139775 IL5RA IL5RA GRIN2B GRIN2B GP9 GP9 ITGB5 ITGB5 GRIA3 GRIA3 ACKR2 ACKR2 TLR2 TLR2 OSMR OSMR LOC102147050 LOC102147050 CSF2 CSF2 TGFB3 TGFB3 CHRNA6 CHRNA6 ICAM1 ICAM1 NIPAL2 NIPAL2 CD8A CD8A EMILIN1 EMILIN1 TLR1 TLR1 ITGA7 ITGA7 CR2 CR2 SLC2A4 SLC2A4 IL20RA IL20RA GRIN1 GRIN1 IL13 IL13 ITGAM ITGAM TSPAN32 TSPAN32 LCK LCK PTCRA PTCRA GRIN2D GRIN2D ENSMFAP00000017173 ENSMFAP00000017173 ITGA2 ITGA2 TF TF AKT1 AKT1 ACVR1B ACVR1B AADACL4 AADACL4 BMPR2 BMPR2 BMP7 BMP7 DLG4 DLG4 CHRNA10 CHRNA10 OLFM3 OLFM3 CHRND CHRND ITGAX ITGAX IL18R1 IL18R1 ITGA8 ITGA8 RAMP1 RAMP1 IL12A IL12A IL4R IL4R CD40 CD40 BIRC2 BIRC2 CHRNB3 CHRNB3 CACNG8 CACNG8 SYK SYK VTN VTN AASDH AASDH ITGAE ITGAE HTR2A HTR2A CHRNA1 CHRNA1 IL18RAP IL18RAP IL1B IL1B CACNG4 CACNG4 BTK BTK ITGA10 ITGA10 LYN LYN GRIA1 GRIA1 ITGA3 ITGA3 SVEP1 SVEP1 CD27 CD27 GRID2 GRID2 IFNAR1 IFNAR1 IFNG IFNG SHISA8 SHISA8 CHRNB4 CHRNB4 ENSMFAP00000025331 ENSMFAP00000025331 CSF2RB CSF2RB HTR3A HTR3A ITGB7 ITGB7 TYK2 TYK2 GRIN3A GRIN3A CALCRL CALCRL TRAF3 TRAF3 GRIN2C GRIN2C TGFBR1 TGFBR1 RAMP3 RAMP3 CD3D CD3D PMP22 PMP22 MYD88 MYD88 IL12RB1 IL12RB1 HTR3C HTR3C GP6 GP6 CHRNB1 CHRNB1 GABBR2 GABBR2 ACVR1C ACVR1C ACVR1 ACVR1 IRS2 IRS2 ERBB4 ERBB4 STAT6 STAT6 CNIH2 CNIH2 ITGA5 ITGA5 CALCB CALCB BMPR1B BMPR1B GRIN2A GRIN2A CALCR CALCR IGF1R IGF1R CHRNA9 CHRNA9 CHRNB2 CHRNB2 CD19 CD19 ITGAL ITGAL ACVR2A ACVR2A CHRNA2 CHRNA2 GP1BB GP1BB IL23R IL23R JAK2 JAK2 ITGAV ITGAV CD28 CD28 IL13RA2 IL13RA2 TGFBR2 TGFBR2 IL31 IL31 IRS4 IRS4 IL1R1 IL1R1 CACNG2 CACNG2 VWC2 VWC2 ITGB1 ITGB1 ITGA1 ITGA1 IL9 IL9 AICDA AICDA IL27RA IL27RA SHISA9 SHISA9 LIME1 LIME1 SDCBP SDCBP ZAP70 ZAP70 SPP1 SPP1 INSR INSR ITGA6 ITGA6 CACNG3 CACNG3 IL6R IL6R INSRR INSRR GP1BA GP1BA NPNT NPNT FCER2 FCER2 MCMDC2 MCMDC2 CD79B CD79B ERBB2 ERBB2 ACVR2B ACVR2B CD4 CD4 DLG3 DLG3 CHRNA5 CHRNA5 ACVRL1 ACVRL1 IRS1 IRS1 CD3G CD3G TRAF5 TRAF5 IFNL1 IFNL1 ERBB3 ERBB3 RNF31 RNF31 GRIK5 GRIK5 VWF VWF IFNAR2 IFNAR2 ITGA2B ITGA2B ITGB8 ITGB8 IL6 IL6 CD8B CD8B ABL1 ABL1 CHRNA4 CHRNA4 GPR156 GPR156 TFRC TFRC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL10RBInterleukin 10 receptor subunit beta. (313 aa)
HJVHemojuvelin BMP co-receptor. (427 aa)
CD247Uncharacterized protein. (168 aa)
ITGADIntegrin subunit alpha D; Belongs to the integrin alpha chain family. (1161 aa)
RAMP2Receptor activity modifying protein 2. (149 aa)
GRIA2Glutamate receptor 2; Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of [...] (883 aa)
AADACL3Arylacetamide deacetylase like 3. (407 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (1011 aa)
IL6STInterleukin 6 signal transducer. (942 aa)
SPNSialophorin. (405 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (662 aa)
CD3ET-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] (198 aa)
CNIH3Cornichon family AMPA receptor auxiliary protein 3. (160 aa)
STAT3Signal transducer and activator of transcription. (802 aa)
CHRNGCholinergic receptor nicotinic gamma subunit. (516 aa)
CCL25C-C motif chemokine ligand 25. (165 aa)
LOC102123076Alpha-amylase. (514 aa)
ADMAdrenomedullin. (185 aa)
HTR3E5-hydroxytryptamine receptor 3E; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (472 aa)
FAM189A1Family with sequence similarity 189 member A1. (502 aa)
CCR9G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (369 aa)
NLRP13NLR family pyrin domain containing 13. (1044 aa)
LRRTM4Leucine rich repeat transmembrane neuronal 4. (591 aa)
ITGB4Integrin beta. (1823 aa)
GRIA4Glutamate receptor 4; Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of [...] (902 aa)
HTR3B5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (441 aa)
TRAT1T cell receptor associated transmembrane adaptor 1. (187 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa)
NIPAL3Uncharacterized protein. (406 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (497 aa)
IFNLR1Interferon lambda receptor 1. (525 aa)
OLFM2Olfactomedin 2. (478 aa)
ENSMFAP00000006091Uncharacterized protein. (507 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
AMHR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (584 aa)
GRIK4Glutamate ionotropic receptor kainate type subunit 4. (959 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1035 aa)
ITGB2Integrin beta. (874 aa)
CD5CD5 molecule. (486 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (753 aa)
IL13RA1Interleukin 13 receptor subunit alpha 1. (425 aa)
GRM1Glutamate metabotropic receptor 1. (1195 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
CHRNA7Uncharacterized protein. (510 aa)
HTR3D5-hydroxytryptamine receptor 3D. (446 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1191 aa)
CD79ACD79a molecule. (180 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (348 aa)
CHRNECholinergic receptor nicotinic epsilon subunit. (493 aa)
TFR2Transferrin receptor 2. (798 aa)
VWC2LVon Willebrand factor C domain-containing protein 2-like; May play a role in neurogenesis. May play a role in bone differentiation and matrix mineralization. (222 aa)
LOC102139775Fibronectin type-III domain-containing protein. (222 aa)
IL5RAInterleukin 5 receptor alpha. (420 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
GP9Glycoprotein IX platelet. (177 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
GRIA3Glutamate receptor 3; Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of [...] (894 aa)
ACKR2Atypical chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (384 aa)
TLR2Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (784 aa)
OSMROncostatin M receptor. (977 aa)
LOC102147050Uncharacterized protein. (155 aa)
CSF2Colony stimulating factor 2. (144 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
CHRNA6Cholinergic receptor nicotinic alpha 6 subunit. (494 aa)
ICAM1Intercellular adhesion molecule 1. (532 aa)
NIPAL2NIPA like domain containing 2. (383 aa)
CD8ACD8a molecule. (235 aa)
EMILIN1Elastin microfibril interfacer 1. (1016 aa)
TLR1Toll-like receptor. (786 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
CR2Complement C3d receptor 2. (1093 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (559 aa)
IL20RAInterleukin 20 receptor subunit alpha. (555 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (960 aa)
IL13Interleukin 13. (146 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1147 aa)
TSPAN32Tetraspanin 32; Belongs to the tetraspanin (TM4SF) family. (320 aa)
LCKTyrosine-protein kinase. (342 aa)
PTCRAPre T cell antigen receptor alpha. (281 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1062 aa)
ENSMFAP00000017173PDZ domain-containing protein. (255 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
TFTransferrin; Belongs to the transferrin family. (698 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
AADACL4Uncharacterized protein. (407 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
CHRNA10Cholinergic receptor nicotinic alpha 10 subunit. (450 aa)
OLFM3Olfactomedin-like domain-containing protein. (478 aa)
CHRNDCholinergic receptor nicotinic delta subunit. (530 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1168 aa)
IL18R1Interleukin 18 receptor 1. (540 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
RAMP1Receptor activity modifying protein 1. (148 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
IL4RInterleukin 4 receptor. (825 aa)
CD40CD40 molecule. (278 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
CHRNB3Cholinergic receptor nicotinic beta 3 subunit. (467 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (320 aa)
SYKTyrosine-protein kinase. (635 aa)
VTNSMB domain-containing protein. (479 aa)
AASDHAminoadipate-semialdehyde dehydrogenase. (1098 aa)
ITGAEIntegrin subunit alpha E; Belongs to the integrin alpha chain family. (1049 aa)
HTR2A5-hydroxytryptamine receptor 2A. (471 aa)
CHRNA1Cholinergic receptor nicotinic alpha 1 subunit. (502 aa)
IL18RAPInterleukin 18 receptor accessory protein. (598 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (302 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
BTKTyrosine-protein kinase. (659 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1352 aa)
LYNTyrosine-protein kinase. (512 aa)
GRIA1Glutamate receptor 1; Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulati [...] (916 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1064 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1. (3228 aa)
CD27CD27 molecule. (260 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (477 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa)
SHISA8Shisa family member 8. (315 aa)
CHRNB4Cholinergic receptor nicotinic beta 4 subunit. (492 aa)
ENSMFAP00000025331Uncharacterized protein. (259 aa)
CSF2RBColony stimulating factor 2 receptor beta common subunit. (897 aa)
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (515 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (798 aa)
TYK2Tyrosine-protein kinase. (1190 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1115 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (472 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1242 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
RAMP3Uncharacterized protein. (192 aa)
CD3DT-cell surface glycoprotein CD3 delta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...] (171 aa)
PMP22Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (160 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] (309 aa)
IL12RB1Interleukin 12 receptor subunit beta 1. (662 aa)
HTR3C5-hydroxytryptamine receptor 3C; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (426 aa)
GP6Glycoprotein VI platelet. (545 aa)
CHRNB1Cholinergic receptor nicotinic beta 1 subunit. (501 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (883 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (488 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
IRS2Insulin receptor substrate 2. (1279 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
CNIH2Cornichon family AMPA receptor auxiliary protein 2. (160 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1098 aa)
CALCBCalcitonin related polypeptide beta. (138 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (517 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
CHRNA9Cholinergic receptor nicotinic alpha 9 subunit. (479 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (502 aa)
CD19CD19 molecule. (557 aa)
ITGALVWFA domain-containing protein. (582 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
CHRNA2Cholinergic receptor nicotinic alpha 2 subunit. (530 aa)
GP1BBGlycoprotein Ib platelet subunit beta. (208 aa)
IL23RInterleukin 23 receptor. (629 aa)
JAK2Tyrosine-protein kinase. (1139 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
CD28IGv domain-containing protein. (234 aa)
IL13RA2Interleukin 13 receptor subunit alpha 2. (388 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
IL31Interleukin 31. (163 aa)
IRS4Insulin receptor substrate 4. (1222 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
IL9Interleukin 9. (145 aa)
AICDAActivation induced cytidine deaminase. (199 aa)
IL27RAInterleukin 27 receptor subunit alpha. (636 aa)
SHISA9Shisa family member 9. (399 aa)
LIME1Uncharacterized protein. (292 aa)
SDCBPUncharacterized protein. (324 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
SPP1Secreted phosphoprotein 1. (314 aa)
INSRTyrosine-protein kinase receptor. (1382 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
CACNG3Voltage-dependent calcium channel gamma-3 subunit; Regulates the trafficking to the somatodendritic compartment and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. (301 aa)
IL6RInterleukin 6 receptor. (468 aa)
INSRRTyrosine-protein kinase receptor. (1301 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (649 aa)
NPNTNephronectin. (610 aa)
FCER2Fc fragment of IgE receptor II. (243 aa)
MCMDC2Minichromosome maintenance domain containing 2. (681 aa)
CD79BCD79b molecule. (252 aa)
ERBB2Receptor protein-tyrosine kinase. (1406 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (518 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (863 aa)
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (468 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
IRS1Insulin receptor substrate 1. (1241 aa)
CD3GT-cell surface glycoprotein CD3 gamma chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...] (181 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
IFNL1Interferon lambda 1. (202 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1353 aa)
RNF31Uncharacterized protein. (1072 aa)
GRIK5Glutamate ionotropic receptor kainate type subunit 5. (980 aa)
VWFVon Willebrand factor. (2813 aa)
IFNAR2Uncharacterized protein. (735 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1039 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (769 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (212 aa)
CD8BIg-like domain-containing protein. (243 aa)
ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase. (901 aa)
CHRNA4Cholinergic receptor nicotinic alpha 4 subunit. (626 aa)
GPR156G protein-coupled receptor 156. (814 aa)
TFRCTransferrin receptor. (760 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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