110 items (Macaca fascicularis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	APBA2	Amyloid beta precursor protein binding family A member 2. (749 aa)
	FRMPD4	FERM and PDZ domain containing 4. (1352 aa)
	DLG1	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (938 aa)
	TAX1BP3	Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. (124 aa)
	SYNJ2BP	Synaptojanin 2 binding protein. (145 aa)
	STXBP4	Syntaxin binding protein 4. (555 aa)
	TJP2	Uncharacterized protein; Belongs to the MAGUK family. (1247 aa)
	ARHGEF12	Rho guanine nucleotide exchange factor 12. (1544 aa)
	PDZD2	PDZ domain containing 2. (2792 aa)
	FRMPD1	FERM and PDZ domain containing 1. (1578 aa)
	TIAM1	T cell lymphoma invasion and metastasis 1. (1591 aa)
	PDLIM3	PDZ and LIM domain 3. (364 aa)
	USH1C	USH1 protein network component harmonin. (899 aa)
	PARD3	Par-3 family cell polarity regulator. (1325 aa)
	PDZD3	PDZ domain containing 3. (505 aa)
	PCLO	Piccolo presynaptic cytomatrix protein. (5181 aa)
	MAGI2	Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1283 aa)
	PDZRN3	PDZ domain containing ring finger 3. (1066 aa)
	NOS1	Nitric oxide synthase 1. (1468 aa)
	PTPN3	Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (913 aa)
	PARD6B	Par-6 family cell polarity regulator beta. (372 aa)
	MPP5	Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
	LMO7	LIM domain 7. (1670 aa)
	PDZK1	PDZ domain containing 1. (519 aa)
	MPP6	Uncharacterized protein; Belongs to the MAGUK family. (582 aa)
	FRMPD2	FERM and PDZ domain containing 2. (1310 aa)
	LDB3	LIM domain binding 3. (732 aa)
	PDLIM1	PDZ and LIM domain 1. (330 aa)
	PDLIM5	PDZ and LIM domain 5. (625 aa)
	PARD6A	Par-6 family cell polarity regulator alpha. (345 aa)
	RIMS2	Regulating synaptic membrane exocytosis 2. (1367 aa)
	PREX2	Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2. (1606 aa)
	APBA1	Amyloid beta precursor protein binding family A member 1. (840 aa)
	SNTB1	Syntrophin beta 1. (538 aa)
	SHANK2	SH3 and multiple ankyrin repeat domains 2. (1742 aa)
	LRRC7	Leucine rich repeat containing 7. (1542 aa)
	SDCBP2	Syndecan binding protein 2. (292 aa)
	IL16	Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 (By similarity). (1331 aa)
	DLG5	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1905 aa)
	DLG4	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
	MAGI1	Membrane associated guanylate kinase, WW and PDZ domain containing 1. (1462 aa)
	PDLIM2	PDZ and LIM domain protein 2; Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity (By similarity). (602 aa)
	LOC102145105	Uncharacterized protein. (971 aa)
	MPDZ	Multiple PDZ domain crumbs cell polarity complex component. (2084 aa)
	GOPC	PDZ domain-containing protein. (462 aa)
	RHPN1	Rhophilin Rho GTPase binding protein 1. (669 aa)
	ERBIN	Erbb2 interacting protein. (1418 aa)
	MAST2	Microtubule associated serine/threonine kinase 2. (1795 aa)
	HTRA2	HtrA serine peptidase 2. (458 aa)
	RAPGEF6	Uncharacterized protein. (1609 aa)
	MAGIX	MAGI family member, X-linked. (332 aa)
	GRIP2	Glutamate receptor interacting protein 2. (1143 aa)
	RHPN2	Rhophilin Rho GTPase binding protein 2. (610 aa)
	DLG2	Discs large MAGUK scaffold protein 2. (975 aa)
	CYTIP	Cytohesin 1 interacting protein. (359 aa)
	SLC9A3R1	Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatoz [...] (358 aa)
	RAPGEF2	Rap guanine nucleotide exchange factor 2. (1701 aa)
	APBA3	Amyloid beta precursor protein binding family A member 3. (575 aa)
	PARD3B	Par-3 family cell polarity regulator beta. (1204 aa)
	PRX	Periaxin. (1419 aa)
	SLC9A3R2	SLC9A3 regulator 2. (311 aa)
	HTRA1	HtrA serine peptidase 1. (481 aa)
	PATJ	Uncharacterized protein. (568 aa)
	MPP7	Membrane palmitoylated protein 7; Belongs to the MAGUK family. (576 aa)
	AFDN	Afadin, adherens junction formation factor. (1781 aa)
	LNX2	Ligand of numb-protein X 2. (690 aa)
	HTRA4	HtrA serine peptidase 4. (476 aa)
	LIMK1	LIM domain kinase 1. (677 aa)
	SHROOM4	Shroom family member 4. (1499 aa)
	GIPC1	GIPC PDZ domain containing family member 1. (333 aa)
	LIMK2	LIM domain kinase 2. (638 aa)
	PTPN4	Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (926 aa)
	PDZRN4	PDZ domain containing ring finger 4. (777 aa)
	PDZD8	PDZ domain containing 8. (1154 aa)
	PSMD9	PDZ domain-containing protein. (223 aa)
	PDZD11	PDZ domain-containing protein. (140 aa)
	MYO18A	Myosin XVIIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2054 aa)
	TJP1	Tight junction protein 1; Belongs to the MAGUK family. (1767 aa)
	PICK1	PRKCA-binding protein; Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive w [...] (415 aa)
	SNTG2	Syntrophin gamma 2. (539 aa)
	SNTG1	Syntrophin gamma 1. (517 aa)
	PPP1R9A	Protein phosphatase 1 regulatory subunit 9A. (1371 aa)
	CARD14	Caspase recruitment domain family member 14. (995 aa)
	RIMS1	Regulating synaptic membrane exocytosis 1. (1692 aa)
	GRIP1	Glutamate receptor interacting protein 1. (1120 aa)
	SYNPO2	Synaptopodin 2. (1261 aa)
	MPP2	Membrane palmitoylated protein 2; Belongs to the MAGUK family. (537 aa)
	PDZD7	PDZ domain containing 7. (1030 aa)
	SIPA1L3	Signal induced proliferation associated 1 like 3. (1777 aa)
	CNKSR2	Connector enhancer of kinase suppressor of Ras 2. (1034 aa)
	SDCBP	Uncharacterized protein. (324 aa)
	PDZD9	PDZ domain-containing protein 9. (264 aa)
	MPP4	Membrane palmitoylated protein 4; Belongs to the MAGUK family. (636 aa)
	SIPA1L1	Signal induced proliferation associated 1 like 1. (1804 aa)
	ARHGEF11	Rho guanine nucleotide exchange factor 11. (1573 aa)
	KIAA1614	KIAA1614. (1192 aa)
	RGS3	Regulator of G protein signaling 3. (916 aa)
	ARHGAP21	Rho GTPase activating protein 21. (1958 aa)
	GRASP	General receptor for phosphoinositides 1 associated scaffold protein. (395 aa)
	PPP1R9B	Protein phosphatase 1 regulatory subunit 9B. (818 aa)
	MAGI3	Membrane associated guanylate kinase, WW and PDZ domain containing 3. (1482 aa)
	LIN7A	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
	SIPA1L2	Signal induced proliferation associated 1 like 2. (1722 aa)
	SNTA1	Syntrophin alpha 1. (505 aa)
	RGS12	Regulator of G protein signaling 12. (1447 aa)
	DVL2	Dishevelled segment polarity protein 2. (736 aa)
	MAST3	Microtubule associated serine/threonine kinase 3. (1311 aa)
	MAST4	Microtubule associated serine/threonine kinase family member 4. (2518 aa)
	LNX1	Ligand of numb-protein X 1. (727 aa)
	INTU	Inturned planar cell polarity protein. (942 aa)

Your Current Organism:

Macaca fascicularis

NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFDN	LMO7	ENSMFAP00000027415	ENSMFAP00000010860	Afadin, adherens junction formation factor.	LIM domain 7.	0.533
AFDN	SDCBP	ENSMFAP00000027415	ENSMFAP00000037736	Afadin, adherens junction formation factor.	Uncharacterized protein.	0.525
AFDN	SDCBP2	ENSMFAP00000027415	ENSMFAP00000017064	Afadin, adherens junction formation factor.	Syndecan binding protein 2.	0.525
AFDN	TJP1	ENSMFAP00000027415	ENSMFAP00000033811	Afadin, adherens junction formation factor.	Tight junction protein 1; Belongs to the MAGUK family.	0.767
AFDN	TJP2	ENSMFAP00000027415	ENSMFAP00000003363	Afadin, adherens junction formation factor.	Uncharacterized protein; Belongs to the MAGUK family.	0.758
APBA1	DLG1	ENSMFAP00000016512	ENSMFAP00000002487	Amyloid beta precursor protein binding family A member 1.	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	0.413
APBA1	DLG2	ENSMFAP00000016512	ENSMFAP00000024144	Amyloid beta precursor protein binding family A member 1.	Discs large MAGUK scaffold protein 2.	0.413
APBA1	DLG4	ENSMFAP00000016512	ENSMFAP00000018582	Amyloid beta precursor protein binding family A member 1.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.406
APBA1	DLG5	ENSMFAP00000016512	ENSMFAP00000017959	Amyloid beta precursor protein binding family A member 1.	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family.	0.421
APBA1	KIAA1614	ENSMFAP00000016512	ENSMFAP00000038029	Amyloid beta precursor protein binding family A member 1.	KIAA1614.	0.505
APBA1	LIN7A	ENSMFAP00000016512	ENSMFAP00000042837	Amyloid beta precursor protein binding family A member 1.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.812
APBA1	MAGI3	ENSMFAP00000016512	ENSMFAP00000042836	Amyloid beta precursor protein binding family A member 1.	Membrane associated guanylate kinase, WW and PDZ domain containing 3.	0.558
APBA1	MPP2	ENSMFAP00000016512	ENSMFAP00000036930	Amyloid beta precursor protein binding family A member 1.	Membrane palmitoylated protein 2; Belongs to the MAGUK family.	0.700
APBA1	MPP4	ENSMFAP00000016512	ENSMFAP00000037866	Amyloid beta precursor protein binding family A member 1.	Membrane palmitoylated protein 4; Belongs to the MAGUK family.	0.505
APBA1	MPP5	ENSMFAP00000016512	ENSMFAP00000010415	Amyloid beta precursor protein binding family A member 1.	Membrane palmitoylated protein 5; Belongs to the MAGUK family.	0.506
APBA1	MPP6	ENSMFAP00000016512	ENSMFAP00000012533	Amyloid beta precursor protein binding family A member 1.	Uncharacterized protein; Belongs to the MAGUK family.	0.700
APBA1	MPP7	ENSMFAP00000016512	ENSMFAP00000026993	Amyloid beta precursor protein binding family A member 1.	Membrane palmitoylated protein 7; Belongs to the MAGUK family.	0.505
APBA1	RIMS1	ENSMFAP00000016512	ENSMFAP00000036213	Amyloid beta precursor protein binding family A member 1.	Regulating synaptic membrane exocytosis 1.	0.441
APBA1	RIMS2	ENSMFAP00000016512	ENSMFAP00000015954	Amyloid beta precursor protein binding family A member 1.	Regulating synaptic membrane exocytosis 2.	0.938
APBA2	DLG5	ENSMFAP00000000020	ENSMFAP00000017959	Amyloid beta precursor protein binding family A member 2.	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family.	0.607

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