STRINGSTRING
DDX39B DDX39B CHD5 CHD5 IFIH1 IFIH1 DHX29 DHX29 DHX15 DHX15 DHX16 DHX16 SUPV3L1 SUPV3L1 CHD4 CHD4 ERCC3 ERCC3 DICER1 DICER1 SMARCAD1 SMARCAD1 TTF2 TTF2 DDX6 DDX6 RAD54L2 RAD54L2 DDX58 DDX58 ERCC6L ERCC6L DDX60L DDX60L BTAF1 BTAF1 DDX21 DDX21 TDRD12 TDRD12 EIF4A2 EIF4A2 DDX49 DDX49 RECQL5 RECQL5 INO80 INO80 HELLS HELLS DDX39A DDX39A DDX50 DDX50 EIF4A3 EIF4A3 SMARCA5 SMARCA5 DDX17 DDX17 DDX54 DDX54 CHD1L CHD1L WRN WRN ERCC6L2 ERCC6L2 DDX18 DDX18 DDX43 DDX43 BLM BLM HLTF HLTF EIF4A1 EIF4A1 HELQ HELQ DHX30 DHX30 DDX31 DDX31 DDX56 DDX56 POLQ POLQ ASCC3 ASCC3 SMARCA1 SMARCA1 DDX24 DDX24 DDX10 DDX10 DDX59 DDX59 CHD8 CHD8 TDRD9 TDRD9 DDX3X DDX3X DDX60 DDX60 CHD3 CHD3 DDX5 DDX5 DDX19A DDX19A DDX51 DDX51 RAD54L RAD54L DDX42 DDX42 CHD1 CHD1 RECQL RECQL FSBP FSBP DHX35 DHX35 DDX20 DDX20 ENSMFAP00000017832 ENSMFAP00000017832 DHX38 DHX38 ATRX ATRX DHX36 DHX36 SRCAP SRCAP CHD6 CHD6 YTHDC2 YTHDC2 ERCC6 ERCC6 CHD2 CHD2 DDX23 DDX23 DDX27 DDX27 ZRANB3 ZRANB3 DDX52 DDX52 FANCM FANCM SNRNP200 SNRNP200 DDX4 DDX4 SHPRH SHPRH DHX40 DHX40 CHD9 CHD9 DDX19B DDX19B DDX55 DDX55 DHX37 DHX37 DDX1 DDX1 DHX58 DHX58 SMARCAL1 SMARCAL1 DHX9 DHX9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DDX39BATP-dependent RNA helicase UAP56/SUB2. (428 aa)
CHD5Chromodomain helicase DNA binding protein 5. (1983 aa)
IFIH1Interferon induced with helicase C domain 1. (1025 aa)
DHX29ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1367 aa)
DHX15DEAH-box helicase 15. (795 aa)
DHX16DEAH-box helicase 16. (1044 aa)
SUPV3L1Suv3 like RNA helicase. (787 aa)
CHD4Uncharacterized protein. (1912 aa)
ERCC3General transcription and DNA repair factor IIH helicase subunit XPB; ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATPase activity of XPB/ERCC3, but not its helicase activity, is required fo [...] (786 aa)
DICER1Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1920 aa)
SMARCAD1Uncharacterized protein. (1026 aa)
TTF2Uncharacterized protein. (1170 aa)
DDX6DEAD-box helicase 6; Belongs to the DEAD box helicase family. (483 aa)
RAD54L2RAD54 like 2. (1467 aa)
DDX58DExD/H-box helicase 58. (722 aa)
ERCC6LERCC excision repair 6 like, spindle assembly checkpoint helicase. (1252 aa)
DDX60LDExD/H-box 60 like. (1712 aa)
BTAF1B-TFIID TATA-box binding protein associated factor 1. (1849 aa)
DDX21DExD-box helicase 21. (783 aa)
TDRD12Uncharacterized protein. (1177 aa)
EIF4A2Eukaryotic initiation factor 4A-II; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). (408 aa)
DDX49DEAD-box helicase 49; Belongs to the DEAD box helicase family. (483 aa)
RECQL5ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (991 aa)
INO80INO80 complex ATPase subunit. (1556 aa)
HELLSHelicase, lymphoid specific. (882 aa)
DDX39ADExD-box helicase 39A. (435 aa)
DDX50DExD-box helicase 50. (737 aa)
EIF4A3Eukaryotic initiation factor 4A-III, N-terminally processed; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expr [...] (412 aa)
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1052 aa)
DDX17DEAD-box helicase 17; Belongs to the DEAD box helicase family. (733 aa)
DDX54ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (883 aa)
CHD1LChromodomain helicase DNA binding protein 1 like. (878 aa)
WRNWRN RecQ like helicase. (1428 aa)
ERCC6L2Uncharacterized protein. (1413 aa)
DDX18RNA helicase. (670 aa)
DDX43DEAD-box helicase 43; Belongs to the DEAD box helicase family. (648 aa)
BLMBLM RecQ like helicase. (1416 aa)
HLTFHelicase like transcription factor. (1013 aa)
EIF4A1Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). (406 aa)
HELQHelicase, POLQ like. (1101 aa)
DHX30DExH-box helicase 30. (1222 aa)
DDX31RNA helicase. (851 aa)
DDX56DEAD-box helicase 56. (546 aa)
POLQDNA polymerase theta. (2721 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3. (2202 aa)
SMARCA1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (1110 aa)
DDX24DEAD-box helicase 24. (856 aa)
DDX10RNA helicase. (962 aa)
DDX59DEAD-box helicase 59. (620 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2589 aa)
TDRD9Tudor domain containing 9. (1366 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (733 aa)
DDX60DExD/H-box helicase 60. (1712 aa)
CHD3Chromodomain helicase DNA binding protein 3. (2000 aa)
DDX5Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...] (614 aa)
DDX19ABrain cDNA, clone: QtrA-13194, similar to human hypothetical protein FLJ11126 (FLJ11126). (478 aa)
DDX51DEAD-box helicase 51; Belongs to the DEAD box helicase family. (664 aa)
RAD54LRAD54 like. (747 aa)
DDX42DEAD-box helicase 42. (937 aa)
CHD1Chromodomain helicase DNA binding protein 1. (1712 aa)
RECQLATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (649 aa)
FSBPUncharacterized protein. (908 aa)
DHX35DEAH-box helicase 35. (703 aa)
DDX20DEAD-box helicase 20. (856 aa)
ENSMFAP00000017832Uncharacterized protein; Belongs to the DEAD box helicase family. (387 aa)
DHX38DEAH-box helicase 38. (1234 aa)
ATRXATRX chromatin remodeler. (2490 aa)
DHX36DEAH-box helicase 36. (1008 aa)
SRCAPUncharacterized protein. (3229 aa)
CHD6Chromodomain helicase DNA binding protein 6. (2718 aa)
YTHDC2YTH domain-containing protein. (660 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1496 aa)
CHD2Uncharacterized protein. (1834 aa)
DDX23DEAD-box helicase 23. (820 aa)
DDX27DEAD-box helicase 27; Belongs to the DEAD box helicase family. (775 aa)
ZRANB3Zinc finger RANBP2-type containing 3. (1124 aa)
DDX52DExD-box helicase 52. (599 aa)
FANCMFA complementation group M. (2050 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2136 aa)
DDX4Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...] (725 aa)
SHPRHSNF2 histone linker PHD RING helicase. (1683 aa)
DHX40DEAH-box helicase 40. (779 aa)
CHD9Chromodomain helicase DNA binding protein 9. (2901 aa)
DDX19BTestis cDNA clone: QtsA-16451, similar to human DEAD (Asp-Glu-Ala-As) box polypeptide 19 (DDX19). (484 aa)
DDX55RNA helicase. (600 aa)
DHX37DEAH-box helicase 37. (1160 aa)
DDX1ATP-dependent RNA helicase DDX1; Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5' single-stranded RNA overhang nuclease activity. Possesses ATPase activity on various RNA, but not DNA polynucleotides. May play a role in RNA clearance at DNA double- strand breaks (DSBs), thereby facilitating the template-guided repair of transcriptionally active regions of the genome. Together with RELA, acts as a coactivator to enhance NF-kappa-B-mediated transcriptional activation. Acts as a positive transcriptional regulator of cyclin CCND2 express [...] (740 aa)
DHX58DExH-box helicase 58. (678 aa)
SMARCAL1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (949 aa)
DHX9DExH-box helicase 9. (1275 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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