Your Input: | |
| | MYCBP2 | MYC binding protein 2. (4751 aa) |
| | MEX3A | Mex-3 RNA binding family member A. (520 aa) |
| | ENSMFAP00000045746 | Zf-rbx1 domain-containing protein. (93 aa) |
| | TOPORS | TOP1 binding arginine/serine rich protein. (1047 aa) |
| | RNF175 | Ring finger protein 175. (328 aa) |
| | LNX1 | Ligand of numb-protein X 1. (727 aa) |
| | TRIM23 | Tripartite motif containing 23. (574 aa) |
| | VPS11 | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa) |
| | RNF167 | Ring finger protein 167. (350 aa) |
| | RNF166 | Ring finger protein 166. (237 aa) |
| | SH3RF3 | SH3 domain containing ring finger 3. (882 aa) |
| | RFPL1 | Uncharacterized protein. (317 aa) |
| | ZNRF1 | Zinc and ring finger 1. (278 aa) |
| | RNF14 | RBR-type E3 ubiquitin transferase. (474 aa) |
| | PJA2 | Praja ring finger ubiquitin ligase 2. (708 aa) |
| | CHFR | Checkpoint with forkhead and ring finger domains. (641 aa) |
| | RNF139 | Ring finger protein 139. (664 aa) |
| | TRIM69 | Tripartite motif containing 69. (499 aa) |
| | RNF212 | Ring finger protein 212. (215 aa) |
| | TRIM7 | Tripartite motif containing 7. (511 aa) |
| | RNF39 | Ring finger protein 39. (420 aa) |
| | RNF220 | E3 ubiquitin-protein ligase RNF220; E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity). Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7- mediated deubiquitination of CTNNB1 and promotes Wnt signaling (By similarity). (566 aa) |
| | CBL | Cbl proto-oncogene. (907 aa) |
| | RBX1 | RING-box protein 1. (108 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa) |
| | TRIM47 | Tripartite motif containing 47. (640 aa) |
| | RNF144A | RBR-type E3 ubiquitin transferase. (292 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | BFAR | Bifunctional apoptosis regulator. (450 aa) |
| | NFXL1 | Nuclear transcription factor, X-box binding like 1. (912 aa) |
| | SHPRH | SNF2 histone linker PHD RING helicase. (1683 aa) |
| | VPS41 | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa) |
| | SIAH2 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (324 aa) |
| | RNF20 | E3 ubiquitin protein ligase; Belongs to the BRE1 family. (975 aa) |
| | DTX4 | Deltex E3 ubiquitin ligase 4. (619 aa) |
| | RNF150 | Ring finger protein 150. (438 aa) |
| | RNF146 | E3 ubiquitin-protein ligase RNF146; E3 ubiquitin-protein ligase that specifically binds poly-ADP- ribosylated (PARsylated) proteins and mediates their ubiquitination and subsequent degradation. May regulate many important biological processes, such as cell survival and DNA damage response. Acts as an activator of the Wnt signaling pathway by mediating the ubiquitination of PARsylated AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex. Acts in cooperation with tankyrase proteins (TNKS and TNKS2), which mediate PARsylation of target proteins AXIN1, AXIN2, BLZF1, CA [...] (360 aa) |
| | LONRF2 | LON peptidase N-terminal domain and ring finger 2. (754 aa) |
| | RNF10 | Ring finger protein 10. (811 aa) |
| | CNOT4 | CCR4-NOT transcription complex subunit 4. (710 aa) |
| | DZIP3 | DAZ interacting zinc finger protein 3. (1208 aa) |
| | KMT2C | Lysine methyltransferase 2C. (4802 aa) |
| | TRIM39 | Tripartite motif containing 39. (518 aa) |
| | TRIM28 | Tripartite motif containing 28. (721 aa) |
| | RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (566 aa) |
| | CBLL1 | E3 ubiquitin-protein ligase Hakai; E3 ubiquitin-protein ligase that mediates ubiquitination of several tyrosine-phosphorylated Src substrates, including CDH1, CTTN and DOK1. Targets CDH1 for endocytosis and degradation. Associated component of the WMM complex, a complex that mediates N6- methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Its function in the WMM complex is unknown; Belongs to the Hakai family. (491 aa) |
| | TTC3 | Tetratricopeptide repeat domain 3. (2010 aa) |
| | MARCHF1 | Membrane associated ring-CH-type finger 1. (545 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (486 aa) |
| | TRIM59 | Uncharacterized protein. (323 aa) |
| | NFX1 | Nuclear transcription factor, X-box binding 1. (1120 aa) |
| | RBBP6 | RB binding protein 6, ubiquitin ligase. (1791 aa) |
| | LOC102141558 | Uncharacterized protein. (286 aa) |
| | TRIM38 | Tripartite motif containing 38. (465 aa) |
| | RNF180 | Ring finger protein 180. (592 aa) |
| | RC3H1 | Ring finger and CCCH-type domains 1. (1141 aa) |
| | TRIM54 | Tripartite motif containing 54. (402 aa) |
| | TRIM37 | Tripartite motif containing 37. (963 aa) |
| | BMI1 | RING-type domain-containing protein. (326 aa) |
| | RNF149 | Ring finger protein 149. (400 aa) |
| | RSPRY1 | RING finger and SPRY domain-containing protein 1. (576 aa) |
| | UHRF1 | Ubiquitin like with PHD and ring finger domains 1. (859 aa) |
| | CCNB1IP1 | Cyclin B1 interacting protein 1. (277 aa) |
| | TRIML1 | Tripartite motif family like 1. (468 aa) |
| | MUL1 | Mitochondrial ubiquitin ligase activator of NFKB 1; Exhibits weak E3 ubiquitin-protein ligase activity, but preferentially acts as a SUMO E3 ligase at physiological concentrations. Plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targete [...] (352 aa) |
| | RNF214 | Ring finger protein 214. (703 aa) |
| | OBI1 | ORC ubiquitin ligase 1. (726 aa) |
| | LOC102115028 | Uncharacterized protein. (449 aa) |
| | TRIM25 | Tripartite motif containing 25. (630 aa) |
| | RNF138 | Ring finger protein 138. (245 aa) |
| | PCGF1 | Polycomb group ring finger 1. (259 aa) |
| | PHRF1 | PHD and ring finger domains 1. (1644 aa) |
| | TRIM21 | Tripartite motif containing 21. (475 aa) |
| | RNF11 | Ring finger protein 11. (154 aa) |
| | RNF125 | E3 ubiquitin-protein ligase RNF125; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins, such as DDX58/RIG-I, MAVS/IPS1, IFIH1/MDA5, JAK1 and p53/TP53. Acts as a negative regulator of type I interferon production by mediating ubiquitination of DDX58/RIG-I at 'Lys-181', leading to DDX58/RIG-I degradation. Mediates ubiquitination and subsequent degradation of p53/TP53. Mediates ubiquitination and subsequent degradation of JAK1. Acts as a positive regulator of T-cell activation. (232 aa) |
| | DTX1 | Deltex E3 ubiquitin ligase 1. (535 aa) |
| | RNF128 | Ring finger protein 128. (428 aa) |
| | RNF32 | RING finger protein 32; May play a role in sperm formation. (362 aa) |
| | MID1 | Midline 1. (667 aa) |
| | DTX2 | Deltex E3 ubiquitin ligase 2. (622 aa) |
| | TRIM4 | Tripartite motif containing 4. (474 aa) |
| | RNF34 | Ring finger protein 34. (376 aa) |
| | PEX2 | Peroxisomal biogenesis factor 2. (323 aa) |
| | RCHY1 | Ring finger and CHY zinc finger domain containing 1. (261 aa) |
| | RNF215 | Ring finger protein 215. (352 aa) |
| | TRAF4 | TNF receptor-associated factor. (470 aa) |
| | SCAF11 | SR-related CTD associated factor 11. (1464 aa) |
| | UBOX5 | U-box domain containing 5. (541 aa) |
| | RNF185 | Ring finger protein 185. (192 aa) |
| | RNF115 | Ring finger protein 115. (304 aa) |
| | SH3RF2 | SH3 domain containing ring finger 2. (729 aa) |
| | RBCK1 | RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa) |
| | AMFR | Autocrine motility factor receptor. (643 aa) |
| | TRIM13 | Tripartite motif containing 13. (409 aa) |
| | RNF141 | Ring finger protein 141. (230 aa) |
| | NSMCE1 | NSE1 homolog, SMC5-SMC6 complex component. (266 aa) |
| | LOC102139163 | Uncharacterized protein. (449 aa) |
| | ANKIB1 | RBR-type E3 ubiquitin transferase. (1012 aa) |
| | TRIM24 | Tripartite motif containing 24. (1050 aa) |
| | TRIM36 | Tripartite motif containing 36. (728 aa) |
| | TRIM52 | Tripartite motif containing 52. (296 aa) |
| | TRAF7 | TNF receptor associated factor 7. (670 aa) |
| | RFPL2 | Ret finger protein like 2. (349 aa) |
| | LNX2 | Ligand of numb-protein X 2. (690 aa) |
| | BIRC7 | Baculoviral IAP repeat containing 7. (298 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | SIAH1 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa) |
| | RNF19B | RBR-type E3 ubiquitin transferase. (675 aa) |
| | RNF43 | RING-type domain-containing protein. (783 aa) |
| | MIB1 | Mindbomb E3 ubiquitin protein ligase 1. (1006 aa) |
| | VPS8 | VPS8 subunit of CORVET complex. (1428 aa) |
| | TRIM5 | Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] (495 aa) |
| | LOC102146332 | Uncharacterized protein. (452 aa) |
| | RNF144B | RBR-type E3 ubiquitin transferase. (303 aa) |
| | RNF19A | RBR-type E3 ubiquitin transferase. (838 aa) |
| | RNF103 | Testis cDNA clone: QtsA-10627, similar to human ring finger protein 103 (RNF103). (684 aa) |
| | LOC102142193 | Uncharacterized protein. (288 aa) |
| | ENSMFAP00000024975 | B30.2/SPRY domain-containing protein. (318 aa) |
| | ANAPC11 | Anaphase promoting complex subunit 11. (180 aa) |
| | CGRRF1 | RING-type domain-containing protein. (332 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (604 aa) |
| | LTN1 | Listerin E3 ubiquitin protein ligase 1. (1766 aa) |
| | TRIM77 | Tripartite motif containing 77. (450 aa) |
| | RNF121 | RING-type domain-containing protein. (327 aa) |
| | LONRF3 | LON peptidase N-terminal domain and RING finger protein 3. (811 aa) |
| | RFWD3 | Ring finger and WD repeat domain 3. (774 aa) |
| | LONRF1 | LON peptidase N-terminal domain and ring finger 1. (675 aa) |
| | TRIM55 | Tripartite motif containing 55. (543 aa) |
| | MKRN2 | Makorin ring finger protein 2. (416 aa) |
| | TRIM67 | Tripartite motif containing 67. (782 aa) |
| | MYLIP | Myosin regulatory light chain interacting protein. (445 aa) |
| | TRAIP | TRAF interacting protein. (469 aa) |
| | LOC102146943 | Uncharacterized protein. (452 aa) |
| | RNF5 | Ring finger protein 5. (180 aa) |
| | CBLC | Cbl proto-oncogene C. (474 aa) |
| | RNFT2 | Ring finger protein, transmembrane 2. (436 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) |
| | TRIM2 | Tripartite motif containing 2. (771 aa) |
| | RNF40 | E3 ubiquitin-protein ligase BRE1B; Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradic [...] (1001 aa) |
| | TRIM9 | Tripartite motif containing 9. (795 aa) |
| | TRIM22 | Tripartite motif containing 22. (498 aa) |
| | RNF17 | RING finger protein 17; Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad-MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. May be involved in spermiogenesis (By similarity). (1624 aa) |
| | RNF207 | Ring finger protein 207. (634 aa) |
| | DCST1 | DC-STAMP domain containing 1. (706 aa) |
| | TRIM63 | Tripartite motif containing 63. (383 aa) |
| | NSD2 | Nuclear receptor binding SET domain protein 2. (1365 aa) |
| | MGRN1 | Mahogunin ring finger 1. (576 aa) |
| | RNF24 | Ring finger protein 24. (169 aa) |
| | RNF169 | Ring finger protein 169. (709 aa) |
| | RNF111 | Ring finger protein 111. (1002 aa) |
| | DTX3L | Deltex E3 ubiquitin ligase 3L. (740 aa) |
| | CBLB | Cbl proto-oncogene B. (982 aa) |
| | MSL2 | MSL complex subunit 2. (577 aa) |
| | BAZ1B | Bromodomain adjacent to zinc finger domain 1B. (1486 aa) |
| | RNF6 | Ring finger protein 6. (701 aa) |
| | TRIM75P | Tripartite motif containing 75, pseudogene. (468 aa) |
| | RNF26 | Ring finger protein 26. (433 aa) |
| | TRIM26 | Tripartite motif containing 26. (542 aa) |
| | RNF123 | Ring finger protein 123. (1311 aa) |
| | RAD18 | RAD18 E3 ubiquitin protein ligase. (505 aa) |
| | LRSAM1 | Leucine rich repeat and sterile alpha motif containing 1. (723 aa) |
| | SH3RF1 | SH3 domain containing ring finger 1. (890 aa) |
| | TRIM61 | Tripartite motif containing 61. (209 aa) |
| | RNF122 | Ring finger protein 122. (155 aa) |
| | RNF130 | Ring finger protein 130. (471 aa) |
| | LOC102142530 | Uncharacterized protein. (488 aa) |
| | RNF113A | Ring finger protein 113A. (344 aa) |
| | LOC102137622 | Uncharacterized protein. (503 aa) |
| | RNF182 | Ring finger protein 182. (247 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1683 aa) |
| | TRIM42 | Tripartite motif containing 42. (723 aa) |
| | TRIM32 | Tripartite motif containing 32. (653 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa) |
| | ZNRF2 | Zinc and ring finger 2. (234 aa) |
| | TRIM15 | Tripartite motif containing 15. (465 aa) |
| | RNF187 | Ring finger protein 187. (237 aa) |
| | RNF151 | Ring finger protein 151. (245 aa) |
| | RNF157 | Ring finger protein 157. (680 aa) |
| | PDZRN3 | PDZ domain containing ring finger 3. (1066 aa) |
| | NEURL1 | Neuralized E3 ubiquitin protein ligase 1. (574 aa) |
| | RNF224 | Ring finger protein 224. (153 aa) |
| | RNF41 | Ring finger protein 41. (317 aa) |
| | RNF126 | Ring finger protein 126. (311 aa) |
| | PCGF2 | Polycomb group ring finger 2. (344 aa) |
| | LOC102115792 | Uncharacterized protein. (452 aa) |
| | RNF2 | Ring finger protein 2. (336 aa) |
| | PCGF5 | Polycomb group ring finger 5. (256 aa) |
| | RNF112 | Ring finger protein 112. (631 aa) |
| | ARIH1 | RBR-type E3 ubiquitin transferase. (455 aa) |
| | PML | Promyelocytic leukemia. (882 aa) |
| | RNF213 | Ring finger protein 213. (5073 aa) |
| | CUL9 | Cullin 9; Belongs to the cullin family. (2517 aa) |
| | ZSWIM2 | Zinc finger SWIM-type containing 2. (633 aa) |
| | PCGF6 | Polycomb group ring finger 6. (350 aa) |
| | TRIM17 | Tripartite motif containing 17. (477 aa) |
| | TRIM10 | Tripartite motif containing 10. (481 aa) |
| | TRIM11 | Tripartite motif containing 11. (468 aa) |
| | TRIM27 | Tripartite motif containing 27. (513 aa) |
| | RNF152 | Ring finger protein 152. (203 aa) |
| | TRIM46 | Tripartite motif containing 46. (759 aa) |
| | DTX3 | Deltex E3 ubiquitin ligase 3. (350 aa) |
| | HLTF | Helicase like transcription factor. (1013 aa) |
| | COP1 | COP1 E3 ubiquitin ligase. (731 aa) |
| | RNF25 | Ring finger protein 25. (470 aa) |
| | LOC102116544 | Uncharacterized protein. (452 aa) |
| | TRIM68 | Uncharacterized protein. (485 aa) |
| | PEX10 | Peroxisome biogenesis factor 10; Somewhat implicated in the biogenesis of peroxisomes. (346 aa) |
| | RFFL | Ring finger and FYVE like domain containing E3 ubiquitin protein ligase. (363 aa) |
