STRINGSTRING
AP1S1 AP1S1 ENSMFAP00000016806 ENSMFAP00000016806 SRPRA SRPRA AP4S1 AP4S1 SEC22C SEC22C COPZ1 COPZ1 YKT6 YKT6 SEC22B SEC22B AP3M1 AP3M1 AP3M2 AP3M2 AP1S3 AP1S3 ENSMFAP00000040975 ENSMFAP00000040975 COPZ2 COPZ2 ENSMFAP00000039077 ENSMFAP00000039077 SEC22A SEC22A AP3S1 AP3S1 TRAPPC1 TRAPPC1 AP1S2 AP1S2 AP4M1 AP4M1 AP2M1 AP2M1 AP2S1 AP2S1 ARCN1 ARCN1 ENSMFAP00000014451 ENSMFAP00000014451
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AP1S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (157 aa)
ENSMFAP00000016806AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (107 aa)
SRPRASRP receptor subunit alpha. (638 aa)
AP4S1Adaptor related protein complex 4 subunit sigma 1. (158 aa)
SEC22CSEC22 homolog C, vesicle trafficking protein; Belongs to the synaptobrevin family. (303 aa)
COPZ1Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (197 aa)
YKT6YKT6 v-SNARE homolog; Belongs to the synaptobrevin family. (198 aa)
SEC22BSEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (215 aa)
AP3M1AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family. (418 aa)
AP3M2AP-3 complex subunit mu-2. (418 aa)
AP1S3AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (164 aa)
ENSMFAP00000040975Uncharacterized protein; Belongs to the synaptobrevin family. (205 aa)
COPZ2Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (210 aa)
ENSMFAP00000039077Uncharacterized protein. (86 aa)
SEC22AVesicle-trafficking protein SEC22a; May be involved in vesicle transport between the ER and the Golgi complex; Belongs to the synaptobrevin family. (307 aa)
AP3S1Adaptor related protein complex 3 subunit sigma 1. (193 aa)
TRAPPC1Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (145 aa)
AP1S2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
AP4M1AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (453 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (458 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
ARCN1Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (552 aa)
ENSMFAP00000014451Uncharacterized protein. (187 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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