STRINGSTRING
PIK3C2G PIK3C2G DOCK8 DOCK8 MAP3K1 MAP3K1 IPO8 IPO8 LOC102120896 LOC102120896 LOC102126330 LOC102126330 NBEA NBEA PPP4R3A PPP4R3A MROH9 MROH9 NCAPG NCAPG RANBP6 RANBP6 SARM1 SARM1 IPO4 IPO4 LTA4H LTA4H TTC12 TTC12 FMNL2 FMNL2 SPAG6 SPAG6 ATR ATR COPG2 COPG2 PIK3C2A PIK3C2A RRN3 RRN3 CTNNB1 CTNNB1 COPB1 COPB1 DIAPH3 DIAPH3 IPO7 IPO7 WDFY3 WDFY3 NCAPG2 NCAPG2 MROH2B MROH2B RIPOR2 RIPOR2 PIK3CB PIK3CB AP3B2 AP3B2 IPO5 IPO5 PELP1 PELP1 PSMD1 PSMD1 PPP2R5C PPP2R5C HEATR3 HEATR3 ELMO1 ELMO1 CKAP5 CKAP5 RNPEP RNPEP AP3B1 AP3B1 VAC14 VAC14 FOCAD FOCAD AGBL1 AGBL1 MTOR MTOR NCAPD3 NCAPD3 MROH7 MROH7 RRP12 RRP12 CIP2A CIP2A PACRG PACRG VPS35 VPS35 IFT172 IFT172 EFR3A EFR3A KPNA4 KPNA4 APC APC TANGO6 TANGO6 ZER1 ZER1 PPP2R1B PPP2R1B NF1 NF1 CUL7 CUL7 ZYG11A ZYG11A FHOD1 FHOD1 KPNA1 KPNA1 DOCK1 DOCK1 SERAC1 SERAC1 PPP4R1 PPP4R1 ARMC4 ARMC4 SDAD1 SDAD1 XPO1 XPO1 ARID2 ARID2 LOC102133124 LOC102133124 HIP1 HIP1 XPO5 XPO5 HSF2BP HSF2BP ARMC12 ARMC12 PSMD2 PSMD2 AP1G1 AP1G1 RSPRY1 RSPRY1 USO1 USO1 CTIF CTIF PPP4R3B PPP4R3B UTP20 UTP20 API5 API5 DNAAF5 DNAAF5 STAG1 STAG1 PPP2R5A PPP2R5A PDS5B PDS5B FRYL FRYL INTS7 INTS7 URB1 URB1 EIF4G1 EIF4G1 RANBP17 RANBP17 TMCO6 TMCO6 TBCD TBCD PIK3C3 PIK3C3 JUP JUP CSE1L CSE1L NCDN NCDN LRBA LRBA RIC8B RIC8B RNPEPL1 RNPEPL1 GCN1 GCN1 NBAS NBAS RYR3 RYR3 TAF2 TAF2 TNPO1 TNPO1 STK36 STK36 MMS22L MMS22L PSME4 PSME4 PSMD5 PSMD5 PKP1 PKP1 DOCK9 DOCK9 PIK3C2B PIK3C2B TEX10 TEX10 PPP6R3 PPP6R3 PPP6R2 PPP6R2 SCYL3 SCYL3 GBF1 GBF1 CUL9 CUL9 MRO MRO ARFGEF2 ARFGEF2 DOCK5 DOCK5 HEATR9 HEATR9 CLASP2 CLASP2 PI4KA PI4KA TOGARAM1 TOGARAM1 PPP2R1A PPP2R1A ARMC7 ARMC7 STAG3 STAG3 ZNFX1 ZNFX1 AP4E1 AP4E1 RAP1GDS1 RAP1GDS1 LRRK2 LRRK2 RPTOR RPTOR EIF4G2 EIF4G2 CFAP69 CFAP69 KPNA5 KPNA5 TOGARAM2 TOGARAM2 HUWE1 HUWE1 CNOT9 CNOT9 KPNA2 KPNA2 FMNL3 FMNL3 PPP2R5E PPP2R5E PIK3CD PIK3CD DOCK3 DOCK3 AP1B1 AP1B1 PPP2R5D PPP2R5D ARMC8 ARMC8 INSC INSC UNC45A UNC45A ITPR1 ITPR1 DIAPH1 DIAPH1 CEBPZ CEBPZ TRIP12 TRIP12 AP2A1 AP2A1 RPAP1 RPAP1 NIPBL NIPBL ECPAS ECPAS MYBBP1A MYBBP1A PPP2R5B PPP2R5B FHOD3 FHOD3 STKLD1 STKLD1 EIF2B5 EIF2B5 MROH2A MROH2A ZYG11B ZYG11B IFRD1 IFRD1 PIK3CA PIK3CA XPO6 XPO6 RIPOR1 RIPOR1 BTAF1 BTAF1 ARMH3 ARMH3 MMS19 MMS19 HEATR1 HEATR1 RELCH RELCH HSPBP1 HSPBP1 ASPM ASPM CAND1 CAND1 CAND2 CAND2 RALGAPA1 RALGAPA1 RSPH14 RSPH14 UPF2 UPF2 ARMC5 ARMC5 CLASP1 CLASP1 HEATR4 HEATR4 LTN1 LTN1 PAIP1 PAIP1 VEPH1 VEPH1 RTTN RTTN PDS5A PDS5A SMG1 SMG1 KPNA3 KPNA3 USP24 USP24 ELMO2 ELMO2 ATM ATM TAF6 TAF6 IPO9 IPO9 MEI1 MEI1 ITPR2 ITPR2 IPO11 IPO11 EIF4G3 EIF4G3 UNC79 UNC79 ARMC9 ARMC9 NCAPD2 NCAPD2 WAPL WAPL HTT HTT SIL1 SIL1 RIC8A RIC8A FMNL1 FMNL1 TSC2 TSC2 AP3D1 AP3D1 ATP6V1H ATP6V1H EIF5 EIF5 DNAJC13 DNAJC13 AP2B1 AP2B1 NOC2L NOC2L IPO13 IPO13 XPOT XPOT RICTOR RICTOR ARID1A ARID1A CLTCL1 CLTCL1 TNPO3 TNPO3 KAT6B KAT6B NOC3L NOC3L MROH1 MROH1 IFRD2 IFRD2 RIF1 RIF1 USP9X USP9X CTNND1 CTNND1 COPG1 COPG1 AP2A2 AP2A2 KPNA7 KPNA7 MROH5 MROH5 PPP4R4 PPP4R4 CAB39L CAB39L ATXN10 ATXN10 KIFAP3 KIFAP3 XPO7 XPO7 ARFGEF1 ARFGEF1 SCYL1 SCYL1 ARMCX5 ARMCX5 PIK3R4 PIK3R4 XPO4 XPO4 BHLHB9 BHLHB9 GPRASP2 GPRASP2 TTI1 TTI1 KPNB1 KPNB1 ENSMFAP00000014047 ENSMFAP00000014047 ULK4 ULK4 ENSMFAP00000013724 ENSMFAP00000013724 SCYL2 SCYL2 LOC102139221 LOC102139221 PKP4 PKP4 TERB1 TERB1 THADA THADA ARMCX1 ARMCX1 INTS4 INTS4 PUM1 PUM1 BZW1 BZW1 ARMC1 ARMC1 AP4B1 AP4B1 KPNA6 KPNA6 CWC22 CWC22 ARMC6 ARMC6 DOCK2 DOCK2 PUM2 PUM2 DOCK11 DOCK11 CAB39 CAB39 ANKAR ANKAR TRRAP TRRAP BRAT1 BRAT1 NBEAL2 NBEAL2 ENSMFAP00000045057 ENSMFAP00000045057 DCAF1 DCAF1 VPS11 VPS11 ARMC2 ARMC2 AGTPBP1 AGTPBP1 CLHC1 CLHC1 NEK10 NEK10 CLTC CLTC ARMC3 ARMC3 RALGAPA2 RALGAPA2 FRY FRY TTI2 TTI2 EIF3K EIF3K BZW2 BZW2 CTNNBL1 CTNNBL1 DAAM2 DAAM2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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PIK3C2GPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1486 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2098 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1683 aa)
IPO8Importin 8. (1037 aa)
LOC102120896MIF4G domain-containing protein. (711 aa)
LOC102126330Importin subunit alpha; Functions in nuclear protein import. (504 aa)
NBEANeurobeachin. (2946 aa)
PPP4R3AProtein phosphatase 4 regulatory subunit 3A. (833 aa)
MROH9Maestro heat like repeat family member 9. (861 aa)
NCAPGNon-SMC condensin I complex subunit G. (1044 aa)
RANBP6Uncharacterized protein. (381 aa)
SARM1Sterile alpha and TIR motif containing 1. (724 aa)
IPO4Importin 4. (1087 aa)
LTA4HLeukotriene A(4) hydrolase; Belongs to the peptidase M1 family. (611 aa)
TTC12Tetratricopeptide repeat protein 12. (731 aa)
FMNL2Formin like 2. (1081 aa)
SPAG6Uncharacterized protein. (509 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa)
COPG2Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (871 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1666 aa)
RRN3RRN3 homolog, RNA polymerase I transcription factor. (651 aa)
CTNNB1Catenin beta 1. (781 aa)
COPB1Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (953 aa)
DIAPH3Diaphanous related formin 3. (1193 aa)
IPO7Importin 7. (973 aa)
WDFY3WD repeat and FYVE domain containing 3. (3526 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1143 aa)
MROH2BMaestro heat like repeat family member 2B. (1585 aa)
RIPOR2RHO family interacting cell polarization regulator 2. (1068 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1072 aa)
AP3B2AP-3 complex subunit beta. (1101 aa)
IPO5Importin 5. (1217 aa)
PELP1Proline, glutamate and leucine rich protein 1. (1180 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa)
HEATR3HEAT repeat containing 3. (680 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
CKAP5Cytoskeleton associated protein 5. (2032 aa)
RNPEPArginyl aminopeptidase. (650 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1063 aa)
VAC14VAC14 component of PIKFYVE complex. (782 aa)
FOCADFocadhesin. (1801 aa)
AGBL1ATP/GTP binding protein like 1. (1053 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
NCAPD3Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1498 aa)
MROH7Uncharacterized protein. (1323 aa)
RRP12Ribosomal RNA processing 12 homolog. (1297 aa)
CIP2ACell proliferation regulating inhibitor of protein phosphatase 2A. (906 aa)
PACRGParkin coregulated. (296 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
IFT172Intraflagellar transport 172. (1749 aa)
EFR3AEFR3 homolog A. (848 aa)
KPNA4Importin subunit alpha; Functions in nuclear protein import. (521 aa)
APCAPC regulator of WNT signaling pathway. (2861 aa)
TANGO6Transport and golgi organization 6 homolog. (1048 aa)
ZER1Zyg-11 related cell cycle regulator. (766 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (667 aa)
NF1Neurofibromin 1. (2849 aa)
CUL7Cullin 7; Belongs to the cullin family. (1780 aa)
ZYG11AZyg-11 family member A, cell cycle regulator. (759 aa)
FHOD1Formin homology 2 domain containing 1. (1184 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (538 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1886 aa)
SERAC1Protein SERAC1; Plays an important role in the phosphatidylglycerol remodeling that is essential for both mitochondrial function and intracellular cholesterol trafficking. May catalyze the remodeling of phosphatidylglycerol and be involved in the transacylation-acylation reaction to produce phosphatidylglycerol-36:1. May be involved in bis(monoacylglycerol)phosphate biosynthetic pathway (By similarity). (654 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (930 aa)
ARMC4Armadillo repeat containing 4. (1044 aa)
SDAD1Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (688 aa)
XPO1Exportin 1. (1071 aa)
ARID2AT-rich interaction domain 2. (1815 aa)
LOC102133124DUF3453 domain-containing protein. (295 aa)
HIP1Huntingtin interacting protein 1. (1038 aa)
XPO5Exportin 5. (1207 aa)
HSF2BPHeat shock transcription factor 2 binding protein. (334 aa)
ARMC12Armadillo repeat containing 12. (367 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (912 aa)
AP1G1AP-1 complex subunit gamma. (817 aa)
RSPRY1RING finger and SPRY domain-containing protein 1. (576 aa)
USO1USO1 vesicle transport factor. (973 aa)
CTIFCap binding complex dependent translation initiation factor. (600 aa)
PPP4R3BProtein phosphatase 4 regulatory subunit 3B. (849 aa)
UTP20UTP20 small subunit processome component. (2785 aa)
API5Apoptosis inhibitor 5. (524 aa)
DNAAF5Uncharacterized protein. (280 aa)
STAG1Stromal antigen 1. (1258 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
PDS5BPDS5 cohesin associated factor B. (1448 aa)
FRYLFRY like transcription coactivator. (3013 aa)
INTS7Integrator complex subunit 7. (962 aa)
URB1URB1 ribosome biogenesis homolog. (2349 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1605 aa)
RANBP17RAN binding protein 17. (1088 aa)
TMCO6Transmembrane and coiled-coil domains 6. (493 aa)
TBCDTubulin folding cofactor D. (1138 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (891 aa)
JUPJunction plakoglobin. (745 aa)
CSE1LChromosome segregation 1 like. (971 aa)
NCDNNeurochondrin. (729 aa)
LRBALPS responsive beige-like anchor protein. (2852 aa)
RIC8BRIC8 guanine nucleotide exchange factor B. (560 aa)
RNPEPL1Arginyl aminopeptidase like 1. (704 aa)
GCN1GCN1 activator of EIF2AK4. (2671 aa)
NBASNeuroblastoma amplified sequence. (2372 aa)
RYR3Ryanodine receptor 3. (4873 aa)
TAF2TATA-box binding protein associated factor 2. (1199 aa)
TNPO1Transportin 1. (898 aa)
STK36Serine/threonine kinase 36. (1315 aa)
MMS22LMMS22 like, DNA repair protein. (1243 aa)
PSME4Proteasome activator subunit 4. (1844 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5; Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5 (By similarity). (508 aa)
PKP1Plakophilin 1. (747 aa)
DOCK9Dedicator of cytokinesis 9; Belongs to the DOCK family. (2104 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
TEX10Testis expressed 10. (929 aa)
PPP6R3Protein phosphatase 6 regulatory subunit 3. (879 aa)
PPP6R2Protein phosphatase 6 regulatory subunit 2. (958 aa)
SCYL3SCY1 like pseudokinase 3. (742 aa)
GBF1Golgi brefeldin A resistant guanine nucleotide exchange factor 1. (1859 aa)
CUL9Cullin 9; Belongs to the cullin family. (2517 aa)
MROProtein maestro. (254 aa)
ARFGEF2ADP ribosylation factor guanine nucleotide exchange factor 2. (1785 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1870 aa)
HEATR9Protein HEATR9. (570 aa)
CLASP2Uncharacterized protein. (1514 aa)
PI4KAPhosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family. (2077 aa)
TOGARAM1TOG array regulator of axonemal microtubules 1. (1772 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A regulatory subunit A. (589 aa)
ARMC7Armadillo repeat containing 7. (198 aa)
STAG3Stromal antigen 3. (1226 aa)
ZNFX1Zinc finger NFX1-type containing 1. (1918 aa)
AP4E1AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. (1098 aa)
RAP1GDS1Rap1 GTPase-GDP dissociation stimulator 1. (608 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1335 aa)
EIF4G2Eukaryotic translation initiation factor 4 gamma 2. (925 aa)
CFAP69Cilia and flagella associated protein 69. (941 aa)
KPNA5Importin subunit alpha; Functions in nuclear protein import. (539 aa)
TOGARAM2TOG array regulator of axonemal microtubules 2. (994 aa)
HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4390 aa)
CNOT9CCR4-NOT transcription complex subunit 9; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down- regulation of MYB- and JUN-dependent transcription. Enhances ligand- dependent transcriptional activity of nuclear hormone receptors. May play a role in cell d [...] (329 aa)
KPNA2Importin subunit alpha; Functions in nuclear protein import. (529 aa)
FMNL3Formin like 3. (1003 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
DOCK3Dedicator of cytokinesis 3; Belongs to the DOCK family. (2035 aa)
AP1B1AP complex subunit beta. (949 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
ARMC8Uncharacterized protein. (673 aa)
INSCINSC spindle orientation adaptor protein. (579 aa)
UNC45AUnc-45 myosin chaperone A. (944 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
DIAPH1Diaphanous related formin 1. (1222 aa)
CEBPZCCAAT enhancer binding protein zeta. (1053 aa)
TRIP12Thyroid hormone receptor interactor 12. (2068 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (977 aa)
RPAP1RNA polymerase II associated protein 1. (1393 aa)
NIPBLNipped-B protein. (2804 aa)
ECPASEcm29 proteasome adaptor and scaffold. (1955 aa)
MYBBP1AMYB binding protein 1a. (1339 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
FHOD3Formin homology 2 domain containing 3. (1620 aa)
STKLD1Serine/threonine kinase-like domain-containing protein STKLD1. (690 aa)
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (721 aa)
MROH2AMaestro heat like repeat family member 2A. (1687 aa)
ZYG11BUncharacterized protein. (383 aa)
IFRD1Uncharacterized protein. (452 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
XPO6Exportin 6. (1125 aa)
RIPOR1RHO family interacting cell polarization regulator 1. (1220 aa)
BTAF1B-TFIID TATA-box binding protein associated factor 1. (1849 aa)
ARMH3Armadillo like helical domain containing 3. (689 aa)
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (1030 aa)
HEATR1HEAT repeat-containing protein 1; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. (2144 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1250 aa)
HSPBP1Hsp70-binding protein 1; Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of target proteins (By similarity). (364 aa)
ASPMAbnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). (3476 aa)
CAND1Cullin associated and neddylation dissociated 1. (1230 aa)
CAND2Cullin associated and neddylation dissociated 2 (putative). (1308 aa)
RALGAPA1Ral GTPase activating protein catalytic alpha subunit 1. (2494 aa)
RSPH14Radial spoke head 14 homolog. (347 aa)
UPF2UPF2 regulator of nonsense mediated mRNA decay. (1272 aa)
ARMC5Armadillo repeat containing 5. (1029 aa)
CLASP1Cytoplasmic linker associated protein 1. (1533 aa)
HEATR4HEAT repeat containing 4. (961 aa)
LTN1Listerin E3 ubiquitin protein ligase 1. (1766 aa)
PAIP1Poly(A) binding protein interacting protein 1. (480 aa)
VEPH1Ventricular zone expressed PH domain containing 1. (833 aa)
RTTNRotatin. (2233 aa)
PDS5APDS5 cohesin associated factor A. (1337 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3660 aa)
KPNA3Importin subunit alpha; Functions in nuclear protein import. (521 aa)
USP24Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family. (2622 aa)
ELMO2Engulfment and cell motility 2. (732 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa)
TAF6TATA-box binding protein associated factor 6. (736 aa)
IPO9Importin 9. (1041 aa)
MEI1Meiotic double-stranded break formation protein 1. (1274 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
IPO11Importin 11. (1015 aa)
EIF4G3Eukaryotic translation initiation factor 4 gamma 3. (1740 aa)
UNC79Unc-79 homolog, NALCN channel complex subunit. (2656 aa)
ARMC9Armadillo repeat containing 9. (818 aa)
NCAPD2Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1399 aa)
WAPLWAPL cohesin release factor. (1190 aa)
HTTHuntingtin. (3118 aa)
SIL1SIL1 nucleotide exchange factor. (468 aa)
RIC8ASynembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)- alpha-GDP complex. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation (By similarity). (530 aa)
FMNL1Formin like 1. (1107 aa)
TSC2TSC complex subunit 2. (1807 aa)
AP3D1AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1215 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (483 aa)
EIF5Eukaryotic translation initiation factor 5. (431 aa)
DNAJC13DnaJ heat shock protein family (Hsp40) member C13. (2243 aa)
AP2B1AP complex subunit beta. (951 aa)
NOC2LNOC2 like nucleolar associated transcriptional repressor. (755 aa)
IPO13Importin 13. (963 aa)
XPOTExportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (962 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1732 aa)
ARID1AAT-rich interaction domain 1A. (2268 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1640 aa)
TNPO3Transportin 3. (923 aa)
KAT6BHistone acetyltransferase KAT6B; Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2- dependent transcriptional activation. May be involved in cerebral cortex development. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity; Belongs to the MYST (SAS/MOZ) family. (2071 aa)
NOC3LNucleolar complex protein 3 homolog. (799 aa)
MROH1Maestro heat like repeat family member 1. (1641 aa)
IFRD2Uncharacterized protein. (510 aa)
RIF1Replication timing regulatory factor 1. (2466 aa)
USP9XUbiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2584 aa)
CTNND1Catenin delta 1. (968 aa)
COPG1Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (874 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (940 aa)
KPNA7Importin subunit alpha; Functions in nuclear protein import. (515 aa)
MROH5Maestro heat like repeat family member 5 (gene/pseudogene). (1318 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (872 aa)
CAB39LCalcium binding protein 39 like. (334 aa)
ATXN10Ataxin-10; Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis. (475 aa)
KIFAP3Kinesin associated protein 3. (803 aa)
XPO7Exportin 7. (1034 aa)
ARFGEF1ADP ribosylation factor guanine nucleotide exchange factor 1. (1849 aa)
SCYL1SCY1 like pseudokinase 1. (808 aa)
ARMCX5Armadillo repeat containing X-linked 5. (558 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
XPO4Exportin 4. (1151 aa)
BHLHB9Protein BHLHb9; May play a role in the control of cellular aging and survival; Belongs to the GPRASP family. (547 aa)
GPRASP2G protein-coupled receptor associated sorting protein 2. (838 aa)
TTI1TELO2 interacting protein 1. (1089 aa)
KPNB1Karyopherin subunit beta 1. (875 aa)
ENSMFAP00000014047Symplekin_C domain-containing protein. (556 aa)
ULK4Unc-51 like kinase 4. (1253 aa)
ENSMFAP00000013724Uncharacterized protein. (117 aa)
SCYL2SCY1 like pseudokinase 2. (933 aa)
LOC102139221WRNPLPNID domain-containing protein. (1042 aa)
PKP4Plakophilin 4. (1192 aa)
TERB1Telomere repeat binding bouquet formation protein 1. (738 aa)
THADATHADA armadillo repeat containing. (1976 aa)
ARMCX1Armadillo repeat containing, X-linked 1. (453 aa)
INTS4Integrator complex subunit 4. (972 aa)
PUM1Pumilio RNA binding family member 1. (1195 aa)
BZW1Basic leucine zipper and W2 domains 1. (451 aa)
ARMC1Armadillo repeat containing 1. (282 aa)
AP4B1AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (739 aa)
KPNA6Importin subunit alpha; Functions in nuclear protein import. (549 aa)
CWC22CWC22 spliceosome associated protein homolog. (900 aa)
ARMC6Armadillo repeat containing 6. (501 aa)
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1725 aa)
PUM2Pumilio RNA binding family member 2. (1065 aa)
DOCK11Dedicator of cytokinesis 11; Belongs to the DOCK family. (2073 aa)
CAB39Calcium binding protein 39. (341 aa)
ANKARAnkyrin and armadillo repeat containing. (1434 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3859 aa)
BRAT1BRCA1 associated ATM activator 1. (821 aa)
NBEAL2Neurobeachin like 2. (2752 aa)
ENSMFAP00000045057Uncharacterized protein. (295 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1493 aa)
VPS11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa)
ARMC2Armadillo repeat containing 2. (867 aa)
AGTPBP1ATP/GTP binding protein 1. (1257 aa)
CLHC1Clathrin heavy chain linker domain-containing protein 1. (586 aa)
NEK10NIMA related kinase 10. (1171 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
ARMC3Armadillo repeat containing 3. (872 aa)
RALGAPA2Ral GTPase activating protein catalytic alpha subunit 2. (1970 aa)
FRYFRY microtubule binding protein. (2973 aa)
TTI2TELO2 interacting protein 2. (508 aa)
EIF3KEukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (218 aa)
BZW2Basic leucine zipper and W2 domain-containing protein 2; May be involved in neuronal differentiation. (519 aa)
CTNNBL1DUF1716 domain-containing protein. (563 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (1077 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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