STRINGSTRING
GML GML PINLYP PINLYP CD59 CD59 LYPD5 LYPD5 CD177 CD177 PLAUR PLAUR LYPD2 LYPD2 ACRV1 ACRV1 LYNX1-SLURP2 LYNX1-SLURP2 TEX101 TEX101 LY6H LY6H LYPD4 LYPD4 LYPD8 LYPD8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GMLGlycosylphosphatidylinositol anchored molecule like. (158 aa)
PINLYPPhospholipase A2 inhibitor and LY6/PLAUR domain containing. (232 aa)
CD59CD59 glycoprotein; Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore (By similarity). (130 aa)
LYPD5LY6/PLAUR domain containing 5. (250 aa)
CD177CD177 molecule. (437 aa)
PLAURUrokinase plasminogen activator surface receptor; Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form (By similarity). (335 aa)
LYPD2LY6/PLAUR domain containing 2. (127 aa)
ACRV1Acrosomal vesicle protein 1. (285 aa)
LYNX1-SLURP2LYNX1-SLURP2 readthrough. (97 aa)
TEX101Testis expressed 101. (262 aa)
LY6HLymphocyte antigen 6H; Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4- containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons (By similarity). (161 aa)
LYPD4LY6/PLAUR domain containing 4. (246 aa)
LYPD8LY6/PLAUR domain containing 8. (238 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
Server load: low (32%) [HD]