STRINGSTRING
GAD1 GAD1 SLC38A2 SLC38A2 ENSMFAP00000000762 ENSMFAP00000000762 SLC6A13 SLC6A13 CPLX1 CPLX1 SLC5A7 SLC5A7 ARL6IP5 ARL6IP5 DNAJC5 DNAJC5 SNAP25 SNAP25 DNAJC5B DNAJC5B SLC17A7 SLC17A7 STX1A STX1A PPFIA4 PPFIA4 SLC6A1 SLC6A1 SLC18A3 SLC18A3 PPFIA3 PPFIA3 SLC1A3 SLC1A3 ENSMFAP00000014202 ENSMFAP00000014202 RAB3A RAB3A RIMS2 RIMS2 SLC18A2 SLC18A2 APBA1 APBA1 VAMP2 VAMP2 PPFIA2 PPFIA2 SLC22A2 SLC22A2 ABAT ABAT TSPOAP1 TSPOAP1 SYN3 SYN3 ENSMFAP00000020173 ENSMFAP00000020173 PPFIA1 PPFIA1 ENSMFAP00000021941 ENSMFAP00000021941 CASK CASK ENSMFAP00000022812 ENSMFAP00000022812 SLC1A2 SLC1A2 ALDH5A1 ALDH5A1 GLS GLS SLC6A12 SLC6A12 CHAT CHAT GLS2 GLS2 LIN7C LIN7C MAOA MAOA ENSMFAP00000029049 ENSMFAP00000029049 NAAA NAAA RIMBP2 RIMBP2 SYN2 SYN2 GAD2 GAD2 RIMS3 RIMS3 SYN1 SYN1 UNC13A UNC13A SLC1A6 SLC1A6 UNC13C UNC13C UNC13B UNC13B SYT1 SYT1 SLC32A1 SLC32A1 RIMS1 RIMS1 STXBP1 STXBP1 CPLX2 CPLX2 SLC1A1 SLC1A1 HSPA8 HSPA8 LIN7B LIN7B SLC1A7 SLC1A7 LIN7A LIN7A SLC6A11 SLC6A11 SLC22A1 SLC22A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GAD1Glutamate decarboxylase 1. (594 aa)
SLC38A2Solute carrier family 38 member 2. (506 aa)
ENSMFAP00000000762Uncharacterized protein; Belongs to the heat shock protein 70 family. (578 aa)
SLC6A13Sodium- and chloride-dependent GABA transporter 2; Sodium-dependent GABA and taurine transporter. In presynaptic terminals, regulates GABA signaling termination through GABA uptake. May also be involved in beta-alanine transport (By similarity). Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A13 subfamily. (609 aa)
CPLX1Complexin-1; Positively regulates a late step in synaptic vesicle exocytosis. Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse. Also involved in glucose-induced secretion of insulin by pancreatic beta-cells (By similarity). (134 aa)
SLC5A7Solute carrier family 5 member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (580 aa)
ARL6IP5PRA1 family protein 3; Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate in a PKC activity- dependent manner. May be involved in membrane traffic. (188 aa)
DNAJC5DnaJ heat shock protein family (Hsp40) member C5. (198 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
DNAJC5BDnaJ heat shock protein family (Hsp40) member C5 beta. (199 aa)
SLC17A7Solute carrier family 17 member 7. (561 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (288 aa)
PPFIA4PTPRF interacting protein alpha 4. (1252 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
SLC18A3Solute carrier family 18 member A3. (532 aa)
PPFIA3PTPRF interacting protein alpha 3. (1194 aa)
SLC1A3Amino acid transporter. (542 aa)
ENSMFAP00000014202Uncharacterized protein; Belongs to the heat shock protein 70 family. (571 aa)
RAB3ARas-related protein Rab-3A; Small GTP-binding protein that plays a central role in regulated exocytosis and secretion. Controls the recruitment, tethering and docking of secretory vesicles to the plasma membrane (By similarity). Upon stimulation, switches to its active GTP-bound form, cycles to vesicles and recruits effectors such as RIMS1, RIMS2, Rabphilin-3A/RPH3A, RPH3AL or SYTL4 to help the docking of vesicules onto the plasma membrane (By similarity). Upon GTP hydrolysis by GTPase-activating protein, dissociates from the vesicle membrane allowing the exocytosis to proceed (By simi [...] (220 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1367 aa)
SLC18A2Solute carrier family 18 member A2. (485 aa)
APBA1Amyloid beta precursor protein binding family A member 1. (840 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (118 aa)
PPFIA2PTPRF interacting protein alpha 2. (1257 aa)
SLC22A2Solute carrier family 22 member 2. (555 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
TSPOAP1TSPO associated protein 1. (1874 aa)
SYN3Synapsin III. (580 aa)
ENSMFAP00000020173PRA1 family protein. (186 aa)
PPFIA1PTPRF interacting protein alpha 1. (1267 aa)
ENSMFAP00000021941Uncharacterized protein. (362 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (926 aa)
ENSMFAP00000022812Uncharacterized protein. (421 aa)
SLC1A2Amino acid transporter. (574 aa)
ALDH5A1Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (535 aa)
GLSGlutaminase. (669 aa)
SLC6A12Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (614 aa)
CHATCholine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (631 aa)
GLS2Glutaminase 2. (602 aa)
LIN7CProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa)
MAOAAmine oxidase. (359 aa)
ENSMFAP00000029049Uncharacterized protein. (1637 aa)
NAAAN-acylethanolamine acid amidase; Belongs to the acid ceramidase family. (363 aa)
RIMBP2RIMS binding protein 2. (1123 aa)
SYN2Synapsin II. (584 aa)
GAD2Glutamate decarboxylase 2. (585 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
SYN1Synapsin I. (705 aa)
UNC13AUnc-13 homolog A. (1592 aa)
SLC1A6Amino acid transporter. (564 aa)
UNC13CUnc-13 homolog C. (2216 aa)
UNC13BUncharacterized protein. (4336 aa)
SYT1Synaptotagmin-1; Calcium sensor that participates in triggering neurotransmitter release at the synapse (By similarity). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (By similarity). It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)- dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-in [...] (422 aa)
SLC32A1Vesicular inhibitory amino acid transporter; Involved in the uptake of GABA and glycine into the synaptic vesicles; Belongs to the amino acid/polyamine transporter 2 family. (525 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1692 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (625 aa)
CPLX2Uncharacterized protein. (134 aa)
SLC1A1Solute carrier family 1 member 1. (524 aa)
HSPA8Uncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa)
LIN7BProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (207 aa)
SLC1A7Amino acid transporter. (560 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
SLC6A11Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (632 aa)
SLC22A1Solute carrier family 22 member 1. (554 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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